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Rheumatic Diseases clinical trials

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NCT ID: NCT06302218 Not yet recruiting - Knee Osteoarthritis Clinical Trials

ESPB vs iPACK+ACB in Total Knee Arthroplasty

Start date: April 1, 2024
Phase: Phase 4
Study type: Interventional

Effect of iPACK block with Adductor Canal Block and ESPB on pain management, and NLR and PLR following knee arthroplasty

NCT ID: NCT06277635 Recruiting - Clinical trials for Rheumatoid Arthritis

Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

To study the effect of silymarin against methotrexate-induced liver injury in rheumatic diseases including rheumatoid arthritis, psoriatric arthritis and psoriasis

NCT ID: NCT06273306 Not yet recruiting - Clinical trials for Arthritis, Rheumatoid

Towards Telemonitoring in Immune-Mediated Inflammatory Diseases: Implementation of a Mixed Attention Model (IMIDOC)

IMIDOC
Start date: March 15, 2024
Phase: N/A
Study type: Interventional

The main objective is to evaluate the implementation of a hybrid care model called the mixed attention model (MAM) in clinical practice and to evaluate whether its implementation improves clinical outcomes compared to conventional follow-up. This is a multicenter prospective observational study involving 360 patients with rheumatoid arthritis (RA) and Spondylarthritis (SpA) from five Spanish Hospitals. Patients will be followed-up by the MAM protocol, which is a care model that incorporates the use of digital tool consisting of a mobile application (App) that patients can use at home and that professionals can review asynchronously to detect incidents and to follow their patients; clinical evolution between face-to-face visits. Another group of patients, whose follow-up will be conducted in accordance with a traditional face-to-face care model, will be assessed as the control group. Sociodemographic characteristics, treatments, laboratory parameters, assessment of tender and swollen joints, visual analogue scale for pain and electronic patient reported outcome reports (ePROs) will be collected for all subjects. In the MAM group, these items will be self-assessed both by the mobile App and during face-to-face visits with rheumatologist, who will do the same for patients included in the traditional care model. Patients will be able to report any incidence related to their disease or treatment through the mobile App.

NCT ID: NCT06263634 Recruiting - Psoriatic Arthritis Clinical Trials

Hand Exercises in Psoriatic Arthritis

Start date: April 5, 2023
Phase: N/A
Study type: Interventional

This study is a randomized controlled study examining the effects of 8-week hand home exercises on grip strength, functionality, disease activity and quality of life in patients with PsA. Individuals participating in the study will be randomly divided into 2 groups. Individuals in the intervention group will perform home exercises consisting of stretching, mobility and strengthening, 4 days a week for 8 weeks, and the patients' compliance with the exercise will be monitored by phone call once a week. Individuals in the control group are on the waiting list and the same home exercise program will be taught to the patients at the end of the study.

NCT ID: NCT06235710 Recruiting - Clinical trials for Rheumatoid Arthritis

Prevalence of Musculoskeletal Complaints in Nursing Home Residents

Start date: January 18, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to investigate the prevalence of joint complaints in nursing home residents with and without dementia. Primary objective: Number of tender or swollen joints. Secondary objectives: 1. Only when it is possible for the nursing home resident to provide us this information: how nursing home residents themselves assess the severity of their joint complaints that day (at that time). If the nursing home resident cannot answer this question (reliably), we use the Pain Assessment Checklist for Seniors with Severe Dementia (PACSLAC-D). 2. Investigate mobility limitations among nursing home residents. 3. To understand whether an accurate (differential) diagnosis for the joint complaints is reported in the electronic files. During the study, a standard physical examination of the musculoskeletal system will performed. Nursing home residents allocated in group 1 (no dementia) also provide an answer on 3 non-incriminating questions (severity of joint complaints, pain in general and general health). Nursing home residents allocated in group 2 (dementia) answer, if possible, 1 non-incriminating question (pain in joints at that moment). These question(s) and the physical examination are also widely used in daily clinical practice. No further incriminating questions or questionnaires will be administered. If the nursing home resident cannot answer this question (reliably), we use the PACSLAC-D.

NCT ID: NCT06233760 Recruiting - Rheumatic Diseases Clinical Trials

Prevalence of Abuse Among Patients With Rheumatic Diseases

Start date: April 1, 2023
Phase:
Study type: Observational

Patients with rheumatic diseases (RD) have a relevant representation in the adult population in Mexico. RD are characterized by their chronic and progressive nature, which can impact functionality during the disease and can present various factors that can be associated with the presence of abuse, among others, economic dependence, decreased physical capacity, and need for care and support in different health processes. Regarding abuse in patients with RD, there is little information in the literature; however, it is possible that the prevalence could be similar to that of the occurrence in older adults since both populations share important states of vulnerability. The study aimed to identify the prevalence of abuse in patients with RD. The study will be conducted in two phases: the first one in which the GAS will be adapted for patients with RD, and this version will be validated in a population of our Institute, and the second one in which, applying the validated instrument, the magnitude of abuse is evaluated, and the factors associated with this phenomenon among patients with RD are explored.

NCT ID: NCT06227468 Recruiting - Healthy Clinical Trials

A Clinical Study to Map the HLA Genomic Region in the Greek Population

GENESIS
Start date: December 12, 2023
Phase:
Study type: Observational

The aim of GENESIS clinical study is to map the HLA genomic region in the Greek population and evaluate possible correlations with selected underlying diseases.

NCT ID: NCT06226792 Completed - Clinical trials for Ankylosing Spondylitis

Muscle Architecture in Ankylosing Spondylitis

Start date: January 18, 2024
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to determine whether there is a decrease in muscle mass and the relationship between lower extremity skeletal muscle mass, muscle strength and disease activity in Ankylosing spondylitis. The main questions it aims to answer are: - Is there a relationship between the muscle thickness and pennation angle of the quadriceps, Gastrocnemius medialis and lateralis, Vastus medialis and lateralis and tibialis anterior muscles with disease activity and muscle strength? - Are there any differences in the results of morphological parameters of lower extremity muscles between Ankylosing spondylitis and voluntary participants? Researchers will compare voluntary participants to see if any difference in lower muscle morphological parameters.

NCT ID: NCT06226376 Recruiting - Fibromyalgia Clinical Trials

Mollii Suit and Fibromyalgia (EXOFIB 2)

Start date: January 8, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to demonstrate the improvement of fibromyalgia syndrome obtained following active stimulation compared to sham, with diminished functional disability and improved health status using Exopulse Molli suit stimulation. The main questions it aims to answer are: Evaluation of pain, fatigue, mood and quality of life changes observed after active stimulation in comparison to sham. Improvement of fibromyalgia syndrome as per the Fibromyalgia Impact Questionnaire (FIQ) Study subjects will participate in: A randomized sham controlled double-blind trial to demonstrate the improvement of pain, quality of life, fatigue and mood in adult patients with fibromyalgia following a 2-week intervention of "active" versus "sham" Exopulse Mollii suit. A 2-week washout period should be enough to prevent a potential carry over effect. After this phase (phase 1), a second open label phase (phase 2) will be proposed for patients to understand the effects of Exopulse Mollii suit employed for 4 weeks (7 sessions per week) on the studied outcomes.

NCT ID: NCT06219603 Completed - Rheumatic Diseases Clinical Trials

Awareness About Rheumatic Diseases in a Sample of Syrian Population

Start date: December 1, 2021
Phase:
Study type: Observational [Patient Registry]

The manuscript describes the level of knowledge and awareness about rheumatic diseases in a Syrian population. we found that awareness of rheumatic diseases is mostly bad and very bad in our sample. Also, we showed how the level of awareness changes due to the change of many factors such as (sex, age, residency, education, marital status, and others ). Our community-based survey was the first conducted in Syria. we have included a total of 641 participants who were directed to the first part of the survey to complete questions around socio-demographic data and awareness questions about rheumatic diseases. We ranked our participants into five levels: excellent, good, average, bad, and very bad. Finally, we compared our results with other 4 original published studies, and we found many Boolean points of similarity and many other inspiring points of difference.