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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT04863352 Completed - Prostate Cancer Clinical Trials

Health Status, Quality of Life and Function in Survivors After Radical Treatment for Prostate Cancer. Part I and IIA

OPS
Start date: May 4, 2021
Phase:
Study type: Observational

In this study, addressing prostate cancer survivors, i.e. men who received potentially curative (radical) treatment two to six years ago, we will investigate if older age at time of treatment is a detrimental factor with respect to long-term quality of life (Qol), health, and function. We will also compare QoL, health and function between the prostate cancer survivors and matched population based cohorts, and thereby provide realistic information on the long-term impact of radical prostate cancer treatment

NCT ID: NCT04862533 Completed - Prostate Cancer Clinical Trials

Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA)

BELA
Start date: February 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of beta-alanine in combination with pelvic floor muscle training (PFMT) compared to PFMT plus placebo in men undergoing radical prostatectomy.

NCT ID: NCT04861415 Recruiting - Prostate Cancer Clinical Trials

SBRT vs. Conventional Fractionation With HDR Boost for Prostate Cancer

SHARP
Start date: December 23, 2020
Phase: N/A
Study type: Interventional

Random assignment between SBRT and conventionally fractionated boost following HDR brachytherapy for prostate cancer.

NCT ID: NCT04861194 Recruiting - Prostate Cancer Clinical Trials

EREctile Function Preservation for Prostate Cancer Radiation Therapy (ERECT)

ERECT
Start date: July 14, 2021
Phase: N/A
Study type: Interventional

Single-arm phase II trial of 70 men with low- or intermediate-risk prostate cancer receiving magnetic resonance guided adaptive radiotherapy (MRgRT) in 5 fractions of 7.25 Gy, additionally sparing the neurovascular bundles, the internal pudendal arteries, the corpora cavernosa, and the penile bulb for erectile function preservation.

NCT ID: NCT04858880 Recruiting - Prostate Cancer Clinical Trials

Personalized Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy.

PROPER2
Start date: April 9, 2021
Phase: Phase 3
Study type: Interventional

A randomized phase III trial to study the effect of adding lymph node irradiation in patients with poor prostate-specific antigen (PSA) response during salvage radiotherapy for biochemical recurrence (0.15 ≤ PSA <0.70 ng/ml) after prostatectomy.

NCT ID: NCT04854993 Completed - Prostate Cancer Clinical Trials

Recovery From dNMB Using Different Sugammadex Doses in Elderly Patients Undergoing Robot-assisted Prostatectomy

RECIR
Start date: July 13, 2021
Phase: Phase 3
Study type: Interventional

The aim of this prospecive randomized study is to evaluate the effects of a dose of sugammadex increased by 50% compared to a standard dose on recovery time from deep neuromuscular block in elderly patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP). Secondary objectives are to evaluate the different extubation time, time to exit from the operating room (OR), lenght of stay in post-anaesthesia care unit (PACU) and safety (hemodynamic parameters and respiratory function).

NCT ID: NCT04854343 Recruiting - Prostate Cancer Clinical Trials

SLPI for Prostate Cancer

Start date: December 1, 2020
Phase:
Study type: Observational

Exploratory study of SLPI expression in human prostate cancer patients This is a no-profit exploratory study about the expression of SLPI in human prostate cancer patients that will enroll about 200 patients admitted for suspect prostate cancer to Careggi University Hospital. We will verify whether an increase SLPI levels in the sera may serve as biomarker of cancer progression.

NCT ID: NCT04853095 Completed - Prostate Cancer Clinical Trials

Effect of Peritoneal Fixation on Lymphocele Formation

PerFix
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The PerFix Trial aims to compare the use of peritoneal fixation technique to standard of care (no fixation) during robot-assisted radical prostatectomy with extended pelvic lymph node dissection (RARP + eLND) for the prevention of symptomatic and radiologic lymphocele formation.

NCT ID: NCT04852224 Completed - Prostate Cancer Clinical Trials

Strength, Aging, and Memory in Prostate Cancer

STAMP
Start date: October 1, 2021
Phase:
Study type: Observational

The objective of this study is to compare changes in neurocognitive function across a 12-month period between three groups: (1) men treated with androgen deprivation therapy (ADT) for prostate cancer (PCa); (2) men under active surveillance for PCa; and (3) men without a history of cancer.

NCT ID: NCT04848909 Active, not recruiting - Prostate Cancer Clinical Trials

Stereotactic Body Radiotherapy (SBRT) Post Prostatectomy

PLUTO-MPC
Start date: June 3, 2021
Phase: N/A
Study type: Interventional

This phase I study will assess the toxicity profile and efficacy of SBRT (Stereotactic body radiotherapy) in patients with localized prostate cancer who are considered candidates for post-prostatectomy radiation.