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Prostate Cancer clinical trials

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NCT ID: NCT06138067 Not yet recruiting - Prostate Cancer Clinical Trials

Patient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients

Start date: April 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to test the utility of patient navigation by comparing high intensity patient navigation to low intensity navigation approaches to improving cancer trial enrollment of patients treated in academic and community cancer centers. Patient navigation is a strategy for increasing patients access to cancer care by helping the participant overcome barriers in the participants communities and within the health care system by providing a bridge between the patient and the health care system. The primary objective of this study is to determine if a high intensity patient navigation program will improve patients enrollment on clinical trial in comparison to a low intensity patient navigation. Participants who agree to participate and are eligible will be randomly assigned to either the high intensity or low intensity approach.

NCT ID: NCT06122584 Not yet recruiting - Prostate Cancer Clinical Trials

Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients With Newly-Diagnosed Prostate Cancer

Start date: January 2024
Phase: Phase 3
Study type: Interventional

This study assess the Diagnostic Performance of [18F]PSMA-1007 PET/CT Imaging in Patients with Newly-Diagnosed High-Risk or Very-High-Risk Prostate Cancer

NCT ID: NCT06117696 Not yet recruiting - Prostate Cancer Clinical Trials

Optimizing the Announcement of Advanced or Metastatic Prostate Cancer Using Animated Videos (CartDiag PROSTATE)

CartDiagPROST
Start date: March 2024
Phase:
Study type: Observational

In hospitals, the standard prostate cancer announcement system is based on oral and written information. To improve this system, we have developed animated videos that retrace the patient's care path. This is an exploratory, controlled, before-and-after, multicenter study designed to assess the effect of a standard announcement system reinforced by animated videos on patients' level of understanding of prostate cancer diagnosis and treatment. Patients' perception of information will be assessed using the EORTC QLQ-INFO25 questionnaire.

NCT ID: NCT06111313 Not yet recruiting - Prostate Cancer Clinical Trials

The University of Miami Adapt (UAdapt) Trial

Start date: June 1, 2024
Phase: Phase 2
Study type: Interventional

The Miami UAdapt Trial is a risk-adapted parallel randomized study using single high-dose radiotherapy (SDRT) to treat favorable and unfavorable risk prostate cancer patients. The primary objective of the study is to determine the proportion of patients with Biochemical and/or Clinical Disease Failure 1 year after completion of radiotherapy (RT).

NCT ID: NCT06099093 Not yet recruiting - Prostate Cancer Clinical Trials

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

Start date: April 2024
Phase: Phase 4
Study type: Interventional

The purpose of this research study is to see how well an imaging test, called 18FDCFPyL prostate specific membrane antigen (PSMA) positron emission tomography (PET), can show the extent of prostate cancer when comparing to 68Ga-PSMA-11 PET/CT (another type of diagnostic scan for prostate cancer).

NCT ID: NCT06062355 Not yet recruiting - Prostate Cancer Clinical Trials

Phase I Clinical Study of HRS-9815 for PET/CT Imaging in Patients With Prostate Cancer

Start date: October 2023
Phase: Phase 1
Study type: Interventional

The study is being conducted to evaluate the the safety, pharmacokinetics, radiation dosimetry of HRS-9815 for PET/CT imaging in adult patients with prostate cancer.

NCT ID: NCT06034431 Not yet recruiting - Prostate Cancer Clinical Trials

Increasing Access to Definitive Treatment for Prostate Cancer

Start date: September 2023
Phase: N/A
Study type: Interventional

Investigators will address the overarching challenge of advancing health equity and reducing disparities in prostate cancer by informing efforts to reduce travel burden in prostate cancer (PCa) treatment access among Black men.

NCT ID: NCT05989854 Not yet recruiting - Prostate Cancer Clinical Trials

The Remote Study: Investigating the Effects or Online Exercise on Quality of Life in Men With Prostate Cancer

Start date: October 2023
Phase: N/A
Study type: Interventional

Currently, there are few opportunities for patients with cancer to have individual exercise guidance, and this has further been impacted by the Covid-19 pandemic. However, during the pandemic the use of virtual/remote platforms has been crucial in delivering care to cancer patients. The investigators think that remote exercise training may also offer a solution to support positive change in prostate cancer patients. As a result, the investigators have developed a remote/online exercise programme to explore this further. This study will explore the effectiveness of an 8-week remote exercise and behavioural support intervention, and whether prostate cancer patients feel they benefit from this. The study also aims to see if this sort of exercise programme can be delivered to more prostate cancer patients in the future. This project is open to men with prostate cancer on long term hormone therapy. The intervention will be comprised of one remote supervised session per week, completed 1-1 using an online platform and up to two additional sessions, depending on its suitability for the patient, will be prescribed as unsupervised home-based exercise.

NCT ID: NCT05982418 Not yet recruiting - Prostate Cancer Clinical Trials

Improvement of RARP Outcomes Via 3D Printed/Virtual Prostate Models

RARP-3D
Start date: July 31, 2023
Phase: N/A
Study type: Interventional

Study the effect 3D printed or 3D virtual prostate models of a patient, when manipulated by surgeons during RARP, has on positive surgical margins and functional outcomes of patients. Our main hypothesis is that there is a reduction of positive resection margins and functional outcomes of patients undergoing RARP when surgeons are presented with 3D printed or 3D virtual patient-specific prostate models during surgery. Specifically, we hypothesize that the anatomical knowledge of surgeons that results from the manipulation of 3D printed/virtual models constructed from automated segmentations reduces positive resection margins and functional outcomes.

NCT ID: NCT05978232 Not yet recruiting - Breast Cancer Clinical Trials

NAVAH Impact on Radiation Therapy Completion in Black Breast & Prostate Cancer Patients

Start date: June 1, 2024
Phase: N/A
Study type: Interventional

African-Americans have disparately limited access to optimal cancer care. They have the highest overall cancer death rate and shortest survival time of any racial or ethnic group in the United States. Elucidation of disparities in access to cancer care are important since previous work has indicated that when equal access to RT in Radiation Therapy Oncology Group (RTOG) prospective randomized trials is granted, race does not independently affect outcomes, a finding similar to work conducted in Level I evidence-proven optimal management of curable neurologic conditions. Breast cancer is the most common cancer in African-American women and Prostate cancer is the most common cancer in African-American men. African-American breast & prostate cancer participants are less likely to receive standard-of-care radiation therapy. Previous work has identified that compared to Caucasian women with breast cancer, African-American women are 48% more likely to have RT omission during treatment, 167% less likely to receive timely completion of RT after breast-conserving surgery, 40% less likely to complete RT, and significantly more likely to experience RT treatment delays. Shorter course radiation therapy may reduce disparities in radiation therapy care facing African-American breast cancer participants.