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Prostate Cancer clinical trials

View clinical trials related to Prostate Cancer.

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NCT ID: NCT00683475 Completed - Prostate Cancer Clinical Trials

A Study of IMC-A12 or Ramucirumab Plus Mitoxantrone and Prednisone in Prostate Cancer

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether IMC-A12 or IMC-1121B (ramucirumab) with Mitoxantrone and Prednisone is effective in the treatment of metastatic androgen- independent prostate cancer (APIC).

NCT ID: NCT00681694 Recruiting - Prostate Cancer Clinical Trials

Long-Term Outcomes of Alternative Brachytherapy Techniques for Early Prostate Cancer

Start date: March 2002
Phase: N/A
Study type: Observational

The purpose of this research study is to assess outcomes of treatment for early prostate cancer. Current treatments for early (non-metastatic) cancer may cause long-term impairments in the patients quality of life. In this study we will compare the outcomes of patients treated with two alternative brachytherapy (seed implants) techniques using a series of questionnaires.

NCT ID: NCT00681148 Withdrawn - Prostate Cancer Clinical Trials

Botulinum Toxin Injection With Prostate Brachytherapy

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to see if botox injection into the prostate during seed implantation (brachytherapy) for prostate cancer a) improves urinary symptoms or avoids need for urinary tract instrumentation over the 6-8 month post-operative period when one wants to avoid manipulating the radioactive seeds, and b) speeds up the drop in PSA. Patients will be randomized to botox vs saline injection, at the completion of the seed implantation procedure.

NCT ID: NCT00678054 Completed - Prostate Cancer Clinical Trials

Study of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) for Patients With Rising Prostate-Specific Antigen (PSA)

Start date: April 1999
Phase: Phase 2
Study type: Interventional

This is a Phase II study to test the efficacy of exogenously administered GM-CSF in prostate cancer patients who have failed definitive local therapy, and have only serologic (PSA) evidence of progression.

NCT ID: NCT00678015 Terminated - Prostate Cancer Clinical Trials

Pharmacokinetic and Efficacy Study of Nordihydroguaiaretic Acid (NDGA) in Non Metastatic Recurrent Prostate Cancer

Start date: May 2008
Phase: Phase 2
Study type: Interventional

This is a Phase II, single center study measuring the pharmacokinetic parameters of NDGA administration and assessing the proportion of patients who experience a 50% decline in PSA.

NCT ID: NCT00676780 Completed - Prostate Cancer Clinical Trials

Green Tea Extract and Prostate Cancer

Start date: May 2004
Phase: Phase 2
Study type: Interventional

The purpose of the study is to see if a green tea extract can beneficially alter several markers of cancer risk and progression.

NCT ID: NCT00676286 Completed - Prostate Cancer Clinical Trials

Biological Investigations in Active Surveillance (BIAS) IGAR 2008 I 19 in Prostate Cancer Using High Field MRI (3 Tesla), PET, and Biomarkers

Start date: November 2008
Phase: Phase 1
Study type: Interventional

This study will use high field MRI (3 Tesla), PET and biomarker to follow prostate cancers and determine if these tests can detect cancers that become aggressive.

NCT ID: NCT00673127 Completed - Prostate Cancer Clinical Trials

Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate Cancer

KHAD
Start date: February 2005
Phase: Phase 2
Study type: Interventional

The combination of ketaconazole and hydrocortisone is commonly used for the treatment of prostate cancer. The purpose of this study is to determine if the addition of a drug called dutasteride to this approved combination will make the combination more effective in treating prostate cancer.

NCT ID: NCT00672594 Completed - Prostate Cancer Clinical Trials

Study of Sunitinib Malate in Patients With Newly Diagnosed Prostate Cancer Prior to Prostatectomy

Start date: July 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to look at blood and tissue samples for changes following the use of Sunitinib malate. Additionally, we would like to find out if the drug, Sunitinib malate, is safe and works in men with prostate cancer. Sunitinib malate , also known as Sutent, is approved by the U.S. Food and Drug Administration (FDA), for treatment of tumors of intestines and kidney but it is being tested in research studies for use in men with prostate cancer.

NCT ID: NCT00670553 Completed - Prostate Cancer Clinical Trials

A Phase I Study of LBH589 (Panobinostat) in Combination With External Beam Radiotherapy for the Treatment of Prostate Cancer, Esophageal Cancer and Head and Neck Cancer

Start date: September 2008
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the feasibility of combined administration of different LBH589 dosages with radiotherapy in order to establish the dosage to be evaluated in future studies.