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Pain clinical trials

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NCT ID: NCT00792311 Completed - Pain Clinical Trials

Tsui Test as a Predictor of Bupivacaine Consumption in Labour Epidurals

Start date: November 2008
Phase: N/A
Study type: Interventional

Low current electrical stimulation test, also called the Tsui test, has been used successfully to confirm the catheter location in the epidural space in various patient populations. The results of this study will show whether or not doing a Tsui test can predict inadequate epidural analgesia early in the course of placing the epidural, so that the appropriate measures could be applied immediately upon gathering unfavorable results.

NCT ID: NCT00792181 Completed - Pain Clinical Trials

To Relieve Pain and Anxiety - an Intervention Study in Ambulance Services

Start date: June 2008
Phase: Phase 1
Study type: Interventional

This is an intervention study focusing on both medical and nursing questions. The study is a joint project between the Ambulance services at four cities in West Sweden and Knowledge and research centre, PreHospen at University of Borås. The aim is to prove the importance of a caring relation between a patient and a caregiver in cases when a caregiver treats a patient with benzodiazepines (Midazolam). The overall aim is to show that knowledge and skills in both caring science and medicine can be applied at the same time in order to relieve pain and anxiety in acute myocardial disease. The nursing intervention involves a professional development course for caregivers. The course is expected to deepen the caregivers' knowledge about the encounter with patients as well as cardiovascular treatment. Following questions are formulated: A. What are the effects regarding relieving pain and anxiety in acute myocardial disease? B. What are the effects regarding circulatory influence? C. What are the effects regarding patients' experiences of the ambulance services? D. What are the effects regarding number of care days in relation to acute myocardial disease? E. What are the effects of patients' disease complications?

NCT ID: NCT00791804 Completed - Pain Clinical Trials

Phase II Study of Inhaled AeroLEF for Analgesia After ACL Knee Surgery

Pain
Start date: February 2004
Phase: Phase 2
Study type: Interventional

To evaluate the safety and efficacy of self-titration to effective analgesia with inhaled AeroLEF in patients with moderate/severe acute pain in the post-surgical setting.

NCT ID: NCT00789620 Completed - Pain Clinical Trials

Effects of Intravenous Lidocaine on Transperitoneal Laparoscopic Urological Surgery

Start date: November 2008
Phase: Phase 3
Study type: Interventional

Effective perioperative analgesia is the key to postoperative rehabilitation. An intriguing body of evidence suggests that short-term administration of intravenous lidocaine may produce pain relief that far exceeds both the duration of infusion and the half-life of the drug. When pain relief is provided, concomitant anal-gesic medication can be reduced, side effects from pain relieving medication minimized with a potential for a more rapid postoperative recovery and less complications. IV application of lidocaine should de-crease the duration of bowel dysfunction. We hypothesise that i.v. application of lidocaine in a standard antiarrythmic dose can significantly improve acute rehabilitation after laparoscopic urological surgery and so shorten the hospital stay (primary outcome). We expect that the intraoperative inflammatory response can significantly be reduced.

NCT ID: NCT00789438 Completed - Pain Clinical Trials

Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia

Start date: October 2008
Phase: N/A
Study type: Observational

The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil. These trials showed a good correlation between SPI and aching procedures and a negative correlation between SPI and the remifentanil dosage. Hence, it was concluded that SPI may be a bedside tool to measure `pain` during surgery. So far, no study investigated SPI during regional anaesthesia.

NCT ID: NCT00789412 Completed - Pain Clinical Trials

Surgical Stress Index as a Tool for Monitoring Analgesia and/or Sedation in Critically Ill Patients

Start date: August 2008
Phase: N/A
Study type: Observational

The hypothesis of the study is: Does the Surgical Stress Index (SSI) correlate with the Behavioral Pain Scale (BPS), the Ramsay Sedation Scale (RSS)and/or the Behavioral Pain Scale(BPV) and can therefore be used to monitor the quality of analgosedation in noncommunicative intensive care unit patients?

NCT ID: NCT00786916 Completed - Pain Clinical Trials

Efficacy of IV Lidocaine at Alleviating Pain Associated With Propofol Infusion in Pediatric Patients Undergoing Sedation

Start date: February 2008
Phase: Phase 4
Study type: Interventional

This protocol describes a double-blind, placebo-controlled trial intended to demonstrate the effectiveness of lidocaine at reducing pain associated wiht propofol infusion for short-term deep sedation in children. Patients will be randomized to receive either placebo (saline) or one of two dosing regimens of IV lidocaine prior to initiating propofol infusion. The efficacy of the differing lidocaine doses will be compared to determine the minimum dose required to safely achieve alleviation of pain. We hypothesize that premedicating with lidocaine will significantly decrease pain experienced by pediatric patients receiving propofol for outpatient sedation.

NCT ID: NCT00781001 Completed - Clinical trials for Painful Diabetic Neuropathy

Efficacy of Inhaled Cannabis in Diabetic Painful Peripheral Neuropathy

Start date: July 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine if vaporized cannabis is effective as an analgesic for the treatment of painful diabetic neuropathy.

NCT ID: NCT00780936 Completed - Pain Clinical Trials

Effects of a Peripheral Nerve Block on Biomarkers of Pain and Inflammation

Start date: October 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn. This is important because it may provide information regarding the way that nerve blocks help with the treatment of pain and in particular provide preemptive analgesia.

NCT ID: NCT00779597 Completed - Pain Clinical Trials

Improvement of Self Management for Oncologic Patients With Pain

Start date: October 2008
Phase: N/A
Study type: Interventional

This study will test the SCION (Self care improvement through oncology nursing)-PAIN program, a multi-modular structured intervention to improve self management in oncologic patients with pain compared to care as usual (standard pain treatment and standard care). The study will determine if the self management skills of the patients continue to be used when the intervention stops, e.g. after discharge from hospital. It is hypothesized that patients who receive the multi-modular structured intervention will have less patient-related barriers to the management of cancer pain.