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Pain clinical trials

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NCT ID: NCT00927004 Completed - Pain Clinical Trials

Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis

Start date: August 2010
Phase: Phase 4
Study type: Interventional

This study aims to better understand the way in which painful osteoarthritis affects different people and whether an anti-inflammatory medication such as Arcoxia (etoricoxib) can help to modify this pain. The study will use questionnaires and tests of pain sensitivity to identify arthritis sufferers with more widespread, nerve-type pain and then to investigate whether a daily dose of Arcoxia is more effective than a placebo pill in reducing these symptoms and improving functional movements. The study will also be comparing the same test results of a small group of subjects without knee pain.

NCT ID: NCT00926887 Completed - Pain Clinical Trials

Low Level Laser Therapy to Reduce Pain After Breast Augmentation Surgery

Start date: September 2005
Phase: N/A
Study type: Interventional

The goal of the clinical study was to see if applying low level laser light therapy to the breasts during breast implant surgery could lessen pain experienced by 24 hours after the surgery.

NCT ID: NCT00926705 Completed - Pain Clinical Trials

Dexmedetomidine Infusion in Hypospadias Surgery

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The investigators hypothesize that giving Dexmedetomidine in combination with Fentanyl for pediatric patients undergoing hypospadias surgery, will reduce the fentanyl requirement for intraoperative and postoperative analgesia.

NCT ID: NCT00926588 Completed - Pain Clinical Trials

Stepped Care to Optimize Pain Care Effectiveness

SCOPE
Start date: October 2009
Phase: Phase 3
Study type: Interventional

Pain is the most common physical symptom in primary care, accounting for an enormous burden in terms of patient suffering, quality of life, work and social disability, and health care and societal costs. Pain is particularly prevalent among veterans. Four major barriers to optimal care include underdetection of pain, inadequate initial treatment, failure to monitor adherence and symptom response, and failure to adjust treatment in patients not responding or intolerant of initial therapy. Therefore, we propose to conduct the Stepped Care to Optimize Pain care Effectiveness (SCOPE) study, a randomized clinical effectiveness trial in primary care.

NCT ID: NCT00922974 Completed - Pain Clinical Trials

Image-Guided Radiosurgery or Stereotactic Body Radiation Therapy in Treating Patients With Localized Spine Metastasis

Start date: November 2009
Phase: Phase 2/Phase 3
Study type: Interventional

RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue. PURPOSE: This randomized phase II/III trial is studying how well image-guided radiosurgery or stereotactic body radiation therapy works and compares it to external-beam radiation therapy in treating patients with localized spine metastasis.

NCT ID: NCT00921505 Completed - Pain Clinical Trials

Effect of Ibuprofen, Paracetamol and Their Combination on Radical Oxygen Species (ROS) Production

Start date: May 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether paracetamol, ibuprofen or their combination can modify generation of radical oxygen species (ROS) from stimulated neutrophils.

NCT ID: NCT00920777 Completed - Pain Clinical Trials

Survey and Cognitive Behavior Therapy for Chronic Fatigue Syndrome/Myalgic Encephalomyelitis

Start date: May 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to analyze income variables in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis, and to analyze the effect of short vs. long Cognitive Behaviour Therapy.

NCT ID: NCT00919113 Completed - Clinical trials for Interstitial Cystitis

Efficacy and Safety Study of Uracyst to Treat Interstitial Cystitis/Painful Bladder Syndrome

Start date: July 2009
Phase: Phase 2
Study type: Interventional

A new device for interstitial cystitis is compared to inactive control to determine if it is safe and effective. The study lasts approximately 7 weeks with a 19-week follow-up period.

NCT ID: NCT00919100 Completed - Pain Clinical Trials

Buzzy Versus Vapocoolant Spray: Pediatric Needle Pain Relief

Start date: April 2008
Phase: N/A
Study type: Interventional

A vibrating cold pack placed proximal to the site of venipuncture will decrease the pain of cannulation when compared to vapocoolant spray.

NCT ID: NCT00914173 Completed - Pain Clinical Trials

Pain Monitoring Using Plurality of Non-invasive Physiological Measurement

Start date: November 2008
Phase: N/A
Study type: Interventional

The clinical trial is intended to implement, validate performances and evaluate efficacy of the pain monitoring device for automated assessment of patient's pain level. The efficacy of the pain monitor will be tested by comparing its results to the patient pain reports towards a given pain stimuli.