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Pain clinical trials

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NCT ID: NCT01052038 Completed - Pain Clinical Trials

Post Operative Sore Throat and Dexamethasone

Start date: January 2010
Phase: Phase 4
Study type: Interventional

Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions. There are several factors that have been shown to contribute to postoperative sore throat such as patient related factors, type of anesthesia and type of surgery. Corticosteroids are also commonly used in the perioperative period to potentiate analgesics and as antiemetics. The preoperative administration of dexamethasone can decrease the incidence and severity of postoperative sore throat which is rated by patients as one of the most undesirable outcomes in the postoperative period.

NCT ID: NCT01047371 Completed - Pain Clinical Trials

Why in Hospital - Factors Determining Time to Discharge Readiness After Arthroplasty Surgery

Start date: January 2010
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate patient related factors determining length of stay in hospital after arthroplasty surgery.

NCT ID: NCT01047241 Completed - Pain Clinical Trials

Nasal Administration of Sufentanil+Ketamine for Procedure-related Pain in Children

Start date: April 2010
Phase: Phase 2
Study type: Interventional

The aim of the study is to investigate the absorption and clinical effect of nasal administration of an analgesic nasal spray containing sufentanil+ketamine for pain related to medical procedures in hospitalized children.

NCT ID: NCT01045993 Completed - Pain Clinical Trials

A Study To Evaluate Methods To Evaluate Back Pain

Start date: February 2010
Phase: N/A
Study type: Interventional

The study is designed to assess methods used in clinical research.

NCT ID: NCT01041378 Completed - Pain Clinical Trials

Efficacy of Intravenous Dexamethasone on Postoperative Caudal Analgesia in Pediatric Orchiopexy

Start date: January 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate postoperative pain control for pediatric patients.

NCT ID: NCT01038609 Completed - Pain Clinical Trials

Hydrocodone/Acetaminophen for Acute Pain Following Bunionectomy

Start date: December 2009
Phase: Phase 2
Study type: Interventional

The primary purpose of this study was to evaluate analgesic efficacy and safety of hydrocodone/acetaminophen extended release compared to placebo in moderate to severe pain following primary unilateral first metatarsal bunionectomy.

NCT ID: NCT01035073 Completed - Pain Clinical Trials

Functional Change and Efficacy of Duloxetine in Patients With Co-Morbid Depression & Soft Tissue Discomfort Syndrome

Start date: April 2006
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine the time course of duloxetine efficacy on the symptoms of Major Depressive Disorder (MDD)and on the symptoms of Soft Tissue Discomfort Syndrome(STDS) via use of 24-hour Actigraphâ„¢ measures. We hypothesize that there will be a reduction in both MDD and STDS symptoms in MDD patients with co-morbid STDS symptoms. We further hypothesize that there will be a rapid improvement in functional outcome ratings and 24-hour activity in MDD patients with co-morbid STDS symptoms which may occur even before the antidepressant effect is observed.

NCT ID: NCT01027611 Completed - Pain Clinical Trials

Patient Assessment of Topical Anesthetic Effectiveness for Intravitreal Injections

Start date: October 2009
Phase: Phase 3
Study type: Interventional

There are currently several different commercially available topical eye drops and gels used to reduce eye discomfort (topical anesthetics) during and after eye injections. Dr. Pollack is performing a research study to evaluate three commercially available topical anesthetics (eye numbing treatments) to determine if individuals have a preference for one over the other. The three topical anesthetics being studied are 1) 0.5% proparacaine hydrochloride (generic, Akorn, Inc), 2) 0.5% proparacaine hydrochloride (generic, Akorn, Inc) PLUS 4% lidocaine hydrochloride topical solution (generic, Roxane Laboratories), and 3) 3.5% lidocaine hydrochloride ophthalmic gel (Akten, Akorn, Inc). These eye anesthetics are NOT experimental medications. They are all commercially available topical anesthetics currently used in our offices and their use is widespread among retina specialists throughout the United States. Dr. Pollack will randomly select one topical anesthetic to use and he will ask you to grade your level of pain associated with the injection procedure. Answering these questions should take less than one minute of your time and your identity will NOT be revealed with the results of this study. The results of this study will be used to inform doctors which eye anesthetics patients find most effective for pain control during eye injections.

NCT ID: NCT01022840 Completed - Pain Clinical Trials

The Preemptive Analgetic Potency of Low Dose S-Ketamine

Miniket
Start date: February 2009
Phase: Phase 3
Study type: Interventional

The primary hypothesis is improved postoperative analgetic quality using S-Ketamine, particularly in patients suffering from chronic pain.

NCT ID: NCT01021696 Completed - Pain Clinical Trials

Pain in Patients With Dementia and Behavioural Disturbances

Start date: November 2009
Phase: Phase 2/Phase 3
Study type: Interventional

In nursing homes (NHs) 80% of the patients have dementia, between 60%-80% exhibit behavioural disturbances (BPSD), and more than 60% have pain. Both pain and BPSD is more common in those with severe dementia. Since older persons with dementia have less communicative skills, suffer from more pain and exhibit more agitation, pain may be a contributing factor in these patients. More than 40% of patients with BPSD are treated with neuroleptics despite described side-effects. There is an urgent need to investigate the impact of individual pain management on BPSD in patients with dementia. It was hypothesized that - pain increase BPSD in patients with dementia - individual pain treatment decrease BPSD in patients with dementia