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Pain clinical trials

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NCT ID: NCT02184273 Completed - Pain Clinical Trials

Efficacy and Tolerability of Nolotil i.v. vs. Placebo i.v. in the Prevention of Postoperative Pain in Children Undergoing Minor Surgery

Start date: March 2002
Phase: Phase 4
Study type: Interventional

Study to assess the analgesic efficacy in the prevention of postoperative pain in children undergoing minor surgery (herniorraphy, tonsillectomy) and to assess the tolerability of Metamizol in this group of patients.

NCT ID: NCT02183051 Completed - Pain Clinical Trials

Study to Compare the the Analgesic Efficacy and Tolerability of Meloxicam Versus Placebo and Ibuprofen in the Treatment of Pain After Surgery of the Third Molar

Start date: April 1998
Phase: Phase 2
Study type: Interventional

To assess the analgesic efficacy and tolerability of meloxicam 15 mg, 7.5 mg, 3.75 mg and 1.875 mg oral (rapid release tablet) compared with placebo and ibuprofen 400 mg and 200 mg administered in a single dose, over an observation period of 6 hours in the treatment of pain after surgery of the third molar.

NCT ID: NCT02169154 Completed - Pain Clinical Trials

A Safety Study to Investigate the Skin Irritancy Potential of Diclofenac-Menthol Gel

Start date: June 1, 2014
Phase: Phase 1
Study type: Interventional

This research study is being conducted to investigate the skin irritancy potential of a new medication which contains two active ingredients (diclofenac and menthol) together in a gel formulation and is being developed to treat mild to moderate pain and inflammation, such as acute sport injuries, sprains and strains.

NCT ID: NCT02168244 Completed - Pain Clinical Trials

Reduction of Pain Caused by Biologic Drugs in Psoriasis

Start date: May 2014
Phase: N/A
Study type: Interventional

Injectable biologic drugs are used as a treatment of psoriasis. These injections can sometimes be associated with pain. In this study the investigators aim to reduce the pain by applying heat or ice to the skin 2-3 minutes before injecting the drug, and to compare the pain to injection without any heat or ice.

NCT ID: NCT02160067 Completed - Pain Clinical Trials

A Dose Proportionality and Bioavailability Assessment of Buprenorphine Transdermal Delivery System Second Generation Patches

Start date: May 2014
Phase: Phase 1
Study type: Interventional

The purpose of this study is to obtain pharmacokinetic data for a dose proportionality and relative bioavailability assessment of 2nd generation BTDS patches compared to 1st generation BTDS patches.

NCT ID: NCT02155166 Completed - Pain Clinical Trials

Effect of Intracervical on the Pain Associated With the Insertion of the LNG-IUS

Start date: February 2012
Phase: N/A
Study type: Interventional

This study has the objective to evaluate the effect of Injectable intracervical anesthesia in comparison with a non-steroidal anti-inflammatory drug (NSAID) on the pain scores immediately after insertion of the levonorgestrel-releasing intrauterine system (LNG-IUS) in women without previous vaginal delivery. H0: There is no difference in terms of pain score between the treatments H1: There will be difference in terms of pain score between treatments

NCT ID: NCT02152163 Completed - Pain Clinical Trials

Assessing the Efficacy of IV Ibuprofen for Treatment of Pain in Orthopedic Trauma Patients

Start date: October 2012
Phase: Phase 4
Study type: Interventional

STUDY OBJECTIVES: 1. To evaluate the effectiveness of around the clock (OTC) IV ibuprofen (8 doses) in decreasing pain in orthopedic trauma patients with fractures of the extremities, face, pelvis and/or ribs compared to patients not receiving the medication. 2. To evaluate the effectiveness of around the clock (OTC) IV ibuprofen (8 doses) in decreasing the use of opioid analgesics among orthopedic trauma patients with fractures of the extremities, face, pelvis, and/or ribs compared to compared to patients not receiving the medication.

NCT ID: NCT02151682 Completed - Pain Clinical Trials

A Study to Look at Tapentadol Tablets in Children and Adolescents in Pain

Start date: April 29, 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Tapentadol has already been studied in adults. This study is needed to find out if tapentadol works and is safe to use in children and adolescents with long-term pain.

NCT ID: NCT02150759 Completed - Pain Clinical Trials

Dexmedetomidine-ketamine in Femur Proximal Fracture Patients

Start date: May 2014
Phase: N/A
Study type: Interventional

- Comparison study of analgesic effects for dexmedetomidine-fentanyl vs dexmedetomidine-ketamine - lateral position for spinal anesthesia in femur proximal fracture patients

NCT ID: NCT02143206 Completed - Pain Clinical Trials

Modifying Exercise for the COPD Patient

Start date: September 2012
Phase:
Study type: Observational

This study will test whether using the Biodex BioStep Semi Recumbent Elliptical for the chronic obstructive pulmonary disease (COPD) patient with arthritic limitations will improve participation in a pulmonary rehab program compared to the Nustep elliptical. The main outcome of participation will be measured by the number of exercise sessions the patient is able to complete during their pulmonary rehabilitation program. In addition, distance walked in six minutes, dyspnea score, rate of perceived exertion (RPE) score, Pain Scale Index score, and finally, the Dartmouth Quality of Life index (DQL) will be assessed in both groups. It is believed that the new machine will provide better overall outcomes compared to the traditional machine.