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Pain clinical trials

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NCT ID: NCT02431624 Completed - Pain Clinical Trials

An Assessment of Buprenorphine Transdermal Delivery System (BTDS) Patch Adhesion

Start date: March 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the adhesion of BTDS patch 40 µg/h.

NCT ID: NCT02427659 Completed - Pain Clinical Trials

VR High Tech Pain Control Burn Wound Care

VRH2O
Start date: November 2011
Phase: N/A
Study type: Interventional

Using virtual reality as a form of distraction for pain during wound care. Virtual reality involves looking into a set of goggles and then moving through a computer-simulated world.

NCT ID: NCT02427464 Completed - Clinical trials for Painful Diabetic Neuropathy

Phase 3 Gene Therapy for Painful Diabetic Neuropathy

Start date: April 2016
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of bilateral intramuscular injections of VM202 versus placebo in the treatment of painful diabetic peripheral neuropathy. A total of 507 of 477 planned participants were randomized in a 2:1 ratio to one of two treatment groups. Note that 500 participants received IP treatment, whereas 7 participants did not receive IP treatment. Treatments - Engensis (VM202) - 336 Engensis of 318 planned participants Control - Placebo (VM202 vehicle) - 164 Placebo of 159 planned participants Randomization were stratified by current use of gabapentin and/or pregabalin.

NCT ID: NCT02424565 Completed - Pain Clinical Trials

Effect of Topical Application of Iodex® Balm on Local Surface Temperature

Start date: May 2015
Phase: Phase 4
Study type: Interventional

The rationale of this study is to map out changes in temperature distribution brought about by topical application of our test product, and use this physiological phenomenon to visualize the onset of action involved in overall mechanism of action of the product.

NCT ID: NCT02423876 Completed - Pain Clinical Trials

Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery

Start date: March 17, 2015
Phase: Phase 3
Study type: Interventional

This randomized clinical trial studies epidural anesthesia within an enhanced recovery pathway (ERP) in reducing pain in patients undergoing gynecologic surgery. An epidural analgesia (pain relief) is a small tube placed in the lower back that numbs the nerves and stops the feeling of pain. It stays in place for several days after surgery and may be helpful for pain control in patients with gynecologic cancer after surgery. ERP is a set of specific steps used before, during, and after surgery by health care providers to care for patients after surgery. ERPs include patient education, not using laxatives before surgery, increasing activity after surgery, and scheduled use of medications for pain and nausea. Giving epidural anesthesia as part of an ERP may improve pain control in patients undergoing gynecologic surgery.

NCT ID: NCT02420951 Completed - Pain Clinical Trials

Local Injection of Local Anesthetic 24 Hours After Knee Replacement Surgery May Decrease Pain for Several More Hours

Start date: October 5, 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if an additional injection of local anesthetic immediately prior to removal of the local anesthetic infiltration catheter on postoperative day one is effective in increasing pain reduction, patient satisfaction or outcome measures following total knee replacement (TKR). It is hypothesized that an additional injection of 30ml of .5% bupivacaine solution immediately before infiltration catheter removal will provide pain reduction, patient satisfaction and outcome measures equal or superior to catheter removal with no additional injection. Patients who are undergoing unilateral total knee replacement (TKR) and choose to participate will be randomly assigned to a treatment group.Patients in group one (treatment group) will receive a 30ml dose of .5% bupivacaine solution injected into the local anesthetic infiltration catheter immediately prior to its removal on postoperative day one. Patients in group two (control group) will receive no additional medication during local anesthetic infiltration catheter removal.

NCT ID: NCT02420301 Completed - Pain Clinical Trials

Effect of Self-administered Exercises on PRMD

Start date: July 2012
Phase: N/A
Study type: Interventional

Objective: To study the effects of self-administered exercises based on tuina techniques on the pain intensity caused by playing related musculoskeletal disorders (PRMD) of professional orchestra musicians, using numeric visual scale (NVS). Method: The investigators performed a prospective, controlled, single-blinded, randomized study with musicians suffering from PRMD. n= 69 musicians were randomly distributed into the experimental and into the control group. After an individual diagnostic assessment, specific tuina self-administered exercises were developed and taught to the participants. Musicians were instructed (educated) to repeat the exercises every day during 3 weeks. Pain intensity was measured by NVS before the intervention and after the 1st, 3rd, 5th, 10th, 15th and 20th days of self-exercising. The procedure was the same for the control group, however the Tuina exercises were executed in non-acupuncture points

NCT ID: NCT02418286 Completed - Pain Clinical Trials

KLOS Study - Korean Medicine Registry for Low Back Pain Patients, a Prospective, Observational, Multicenter, Pilot Study

KLOS
Start date: March 2015
Phase:
Study type: Observational [Patient Registry]

The Purpose of this trial is to define the characteristics of the in/outpatients with low back pain in traditional Korean medicine rehabilitation clinic. This information will create a registry that will help us to compare similarities and differences in patients and their symptoms. The more patients the investigators are able to enter into the registry, the more the investigators will be able to understand the low back pain and learn better ways of caring for patients.

NCT ID: NCT02418182 Completed - Pain Clinical Trials

A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval

Start date: January 2015
Phase: Phase 4
Study type: Interventional

Current standard of care is no pretreatment medications before the egg retrieval, and the investigators would like to evaluate if preoperative Tylenol improves procedure and post procedure pain control over the current practice (no pre-treatment). Specifically, this study will compare Tylenol with a placebo when given before retrieval procedures. The investigators believe that if Tylenol can offer better analgesic relief than no pretreatment medications, then it may reduce the amount of narcotics needed by patients during and after the procedure and contribute to better patient satisfaction. . This study will enroll 100 participants all from University of Alabama at Birmingham (UAB).

NCT ID: NCT02418026 Completed - Pain Clinical Trials

Improving Cesarean Section Experience Through Hypnotherapy

Start date: February 2013
Phase: N/A
Study type: Interventional

Cesarean section rates continue to increase worldwide, particularly in middle- and high-income countries. In France, the rate has now stabilized around 20 %. Cesarean section is a particular way of giving birth, sometimes desired, but sometimes feared. If some women do not feel affected by this way of giving birth, it is more difficult for others to live with. In this way, not being able to give birth trough natural way may be disturbing in motherhood. At La Rochelle hospital, more than 230 healthcare providers have been trained according to Erickson's hypnosis methodology. Among them, 40 are part of the anesthesia department and a committee oversees the hypnotherapist activities in pain management. The objective of the present study is to assess the benefit of hypnosis session for improving experience and reducing anxiety in women giving birth through surgery.