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Pain, Postoperative clinical trials

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NCT ID: NCT05664542 Recruiting - Postoperative Pain Clinical Trials

Erector Spinae Block With Ropivacaine and Dexmedetomidine on Opioid Consumption After Lumar Spine Surgeries

Start date: December 15, 2022
Phase: Phase 4
Study type: Interventional

The aim of this study is to investigate the role of 0.5 micrograms/kg of dexmedetomidine with 0.2 % ropivacaine in erector spinae block in reducing opioid consumption for patients undergoing lumbar spine surgeries. This study will help in understanding the role of adding dexmdetomidine to ropivacaine in erector spinae block in reducing opioid consumption after lumbar spine surgeries

NCT ID: NCT05663658 Completed - Obesity Clinical Trials

External Oblique Intercostal Plane Block for Laparoscopic Sleeve Gastrectomy

Start date: December 23, 2022
Phase: N/A
Study type: Interventional

The external oblique intercostal (EOI) plane block is a novel approach upper abdominal wall analgesia. The EOI plane block can provide dermatomal sensory blockade of T6-T10 at the anterior axillary line and T6-T9 at the midline. It may be used for postoperative analgesia in obese patients because it is superficial and rapidly identifiable and performed in the supine position. the aim of this study is to investigate the postoperative analgesic efficacy of external oblique intercostal plane block in obese patients undergoing laparoscopic sleeve gastrectomy. Researchers will compare the external oblique intercostal plane block group with control group to see if the EOI plane block is effective for postoperative analgesia in patients undergoing sleeve gastrectomy.

NCT ID: NCT05662371 Recruiting - Pain, Postoperative Clinical Trials

Influence of Nociception Level Monitor (NOL) Guided Analgesic Delivery on Robot-assisted Colorectal Surgery

Start date: August 1, 2023
Phase: N/A
Study type: Interventional

Being relatively new, the NOL monitor may offer interesting observations in perioperative nociception levels and appropriate analgesic consumption in diverse surgeries, including robot-assisted surgery. These observations may supplement the current efforts towards further advantages in rapid restitution. Therefore, the investigators planned a trial where intra-operative analgesics were guided using an NOL monitor to study if intra-operative NOL guidance influences peri-operative analgesic consumption, postoperative length of stay and quality of recovery of patients subjected for robot-assisted surgery.

NCT ID: NCT05661279 Recruiting - Postoperative Pain Clinical Trials

Rhomboid Intercostal Block Versus Serratus Anterior Plane Block

Start date: December 30, 2022
Phase: N/A
Study type: Interventional

evaluate and compare the impact of ultrasound guided rhomboid intercostal block versus serratus anterior plane block for analgesia after thoracodorsal artery perforator flap following partial mastectomy

NCT ID: NCT05661253 Recruiting - Clinical trials for Postoperative Pain, Acute

Modified Versus Conventional Serratus Anterior Plane Block

Start date: December 2, 2022
Phase: N/A
Study type: Interventional

comparing preemptive analgesia with ultrasound guided modified serratus anterior plane block versus ultrasound guided serratus anterior plane block

NCT ID: NCT05659823 Completed - Pain, Postoperative Clinical Trials

Postoperative Pain After Caesarian Section

Start date: November 2, 2020
Phase: Phase 4
Study type: Interventional

To examine if perioperative pain/nausea/pruritus is altered when current standard analgesia for caesarian section (CS) is replaced with new guideline recommended analgesia.

NCT ID: NCT05657704 Recruiting - Postoperative Pain Clinical Trials

Utility of CYP2D6 Genotyping to Improve the Efficacy and Safety of Tramadol

Tradol-PriME
Start date: October 5, 2022
Phase: Phase 4
Study type: Interventional

Randomized clinical trial to evaluate the utility of CYP2D6 genotyping to improve the efficacy and safety of tramadol in the treatment of acute postoperative pain. Phase IV and low-intervention trial To evaluate if the implementation of pharmacogenetics in clinical practice can help to improve the treatment of acute pain, increasing efficacy and reducing adverse reactions. The main evaluation variable: This is a simple study, which does not differ from standard clinical practice and therefore we do not expect early ending of the study.

NCT ID: NCT05656872 Completed - Postoperative Pain Clinical Trials

Transverse Abdominis Plane Block Versus Ilioinguinal-iliohypogastric Block For Analgesia Following Hysterectomy

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

The investigators hypothesis that ilioinguinal iliohypogastric nerves block could provide a potent modality of postoperative pain control as compared to Transverse Abdominis Plane block in open abdominal hysterectomy

NCT ID: NCT05656625 Completed - Pain, Postoperative Clinical Trials

Comparison of Ultrasound-guided Brachial Plexus Blocks and Selective Distal Blocks in Terms of Anesthesia

Start date: December 20, 2022
Phase:
Study type: Observational

Ultrasound-guided brachial plexus blocks (infraclavicular, axillary) can be applied as the main anesthetic method in hand and wrist surgeries, as well as single or combination block applications of the median, radial and ulnar nerves at the forearm level. Here, we aimed to retrospectively evaluate the perioperative and postoperative data of patients who underwent hand and wrist surgery under distal nerve blocks and brachial plexus blocks in our hospital.

NCT ID: NCT05654363 Completed - Pain, Postoperative Clinical Trials

Observational Retrospective Study on Spinal Analgesia in Laparoscopic and Laparotomic Hysterectomy

SPIN_GYN
Start date: March 13, 2023
Phase:
Study type: Observational

Perioperative multimodal analgesia, defined by the use of various analgesic medications targeting different drug receptors, provides adequate pain relief with minimal or no opiate consumption. Therefore, it represents one of the cornerstone of Enhanced Recovery After Surgery (ERAS) protocols, as the reduction in opioid use and the associated side effects may eventually reduce length of hospital stay, increase patient satisfaction and minimise the risk of long-term opioid use. Regional and neuraxial anesthesia techniques are key interventions to provide successful analgesia in the context of a multimodal strategy. Intrathecal morphine, for its effectiveness and potential of reducing the need of intravenous postoperative opioids, seems an attractive option in the case of hysterectomy, one of the most common major surgical procedures performed in women, associated with severe postoperative pain even when performed laparoscopically. The aim of our observational retrospective study is therefore to compare the analgesic efficacy and the safety of morphine administered by intrathecal route versus intravenous route during the first 48 hours after performance of laparoscopic/laparotomic hysterectomy.