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Pain, Postoperative clinical trials

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NCT ID: NCT00143169 Completed - Pain, Postoperative Clinical Trials

Morphine-Sparing Effect And Safety Of Parecoxib Administered Intravenously For The Treatment Of Postoperative Pain

Start date: September 2004
Phase: Phase 3
Study type: Interventional

To validate the morphine-sparing effect and safety of parecoxib administered intravenously for the treatment of Chinese subjects with postoperative pain following gynecological or orthopedic surgery.

NCT ID: NCT00142519 Completed - Pain Clinical Trials

Comparison of A Single Dose Combination of Methadone and Morphine With Morphine Alone for Treating Post-operative Pain

Start date: March 2005
Phase: Phase 2
Study type: Interventional

This is a randomized Phase II study testing the effectiveness of the combination of morphine and methadone versus morphine alone in relieving pain. A second goal is to further evaluate any side effects of the combination of morphine and methadone.

NCT ID: NCT00140920 Terminated - Pain Clinical Trials

A Study of Rofecoxib in the Treatment of Post-Operative Pain After Total Knee Joint Replacement (0966-259)

Start date: May 25, 2004
Phase: Phase 4
Study type: Interventional

A study to compare pre-operative administration of rofecoxib versus post-operative administration of diclofenac or rofecoxib, respectively, in the treatment of post-operative pain after total knee joint replacement in patients with osteoarthritis of the knee.

NCT ID: NCT00136682 Completed - Postoperative Pain Clinical Trials

Patient-Controlled Epidural Analgesia (PCEA) for Patients Who Have Had Major Open Gynecologic Surgery

Start date: August 2004
Phase: Phase 3
Study type: Interventional

Recovery after major abdominal surgery can be longer than other types of surgery. This is because often after abdominal surgery, the bowel does not work normally. When this happens, patients are unable to pass gas. This can lead to bloating, pain, nausea and vomiting. These symptoms are called postoperative ileus. We, the researchers at Memorial Sloan-Kettering Cancer Center (MSKCC), are doing this study to compare two methods of treating pain during and after major gynecological surgery. The two methods are called patient-controlled epidural analgesia (PCEA) and patient-controlled intravenous analgesia (PCA). PCA is the standard of care for women having major gynecological surgery. We are going to compare PCEA to PCA to see if PCEA will improve recovery after major gynecologic surgery. PCEA is a well established method used to ease pain in many settings such as during childbirth and bowel surgery. There have been several studies showing that PCEA is as good as and sometimes better for pain relief than PCA. PCEA may help the bowel work better by preventing ileus after surgery. However, this has never been looked at in women having major gynecologic surgery. This study will also look at whether preventing this ileus will lead to patients going home or returning to regular activities sooner.

NCT ID: NCT00133133 Completed - Postoperative Pain Clinical Trials

Efficacy and Safety of ALGRX 4975 in the Treatment of Postoperative Pain After Gall Bladder Removal

Start date: July 2005
Phase: Phase 2
Study type: Interventional

Postoperative pain after gall bladder removal can be significant, mobility limiting and extend hospital stay. ALGRX 4975 is an ultra-pure form of capsaicin, which is a pain medicine that has the potential for long-term pain relief following a single administration. This study will determine whether ALGRX 4975 can provide pain relief following gall bladder removal.

NCT ID: NCT00104533 Completed - Postoperative Pain Clinical Trials

Effectiveness of Magnetic Therapy on Pain Intensity

Start date: September 2004
Phase: Phase 3
Study type: Interventional

Static magnetic therapy is increasingly used to alleviate pain; however, its efficacy has not been determined yet. The aims of this proposal are to evaluate the effect of magnetic therapy on pain intensity levels, opioid requirements, and opioid side effects.

NCT ID: NCT00092378 Completed - Postoperative Pain Clinical Trials

A Study of Two Approved Drugs in the Treatment of Post-Bunionectomy Surgery Pain (0966-234)(COMPLETED)

Start date: September 1, 2003
Phase: Phase 3
Study type: Interventional

This purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following bunionectomy surgery.

NCT ID: NCT00092339 Completed - Postoperative Pain Clinical Trials

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-190)(COMPLETED)

Start date: August 1, 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

NCT ID: NCT00092326 Completed - Postoperative Pain Clinical Trials

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-183)

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.

NCT ID: NCT00092313 Completed - Postoperative Pain Clinical Trials

A Study of Two Approved Drugs in the Treatment of Postoperative Dental Pain (0966-182)

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of two approved drugs in the treatment of pain following dental surgery.