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Pain, Postoperative clinical trials

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NCT ID: NCT03312153 Not yet recruiting - Pain Clinical Trials

Effect of Neem and NaOCl on Postoperative Pain and Amount of Endotoxins

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effect of Neem (azadirachta indica) and 2.5% sodium hypochlorite as root canal irrigants on the intensity of post-operative pain and the amount of endotoxins in necrotic teeth.

NCT ID: NCT03296189 Not yet recruiting - Pain, Postoperative Clinical Trials

Local Anaesthetic and Steroid in the Ureter

LASTE
Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Précis: Randomised control trial to evaluate safety and efficacy of intraluminal injection of high pH-high concentration of a long-acting local anesthetic and long-acting glucocorticoid in the ureter after ureteroscopy. Objectives: To evaluate a novel method to ameliorate post-ureteroscopy pain in all patients (with and without stents) Endpoints: Primary endpoint: mean visual analog pain scale (VAS) post-operatively starting at 1 hour, 4 hours, 8 hours, 24 hours and 7 days post-procedure (minimum of 3 VAS scores). VAS pain, ureteral stent symptoms and analgesic requirement will be assessed at different points during this time period. Secondary endpoint: Postoperative Nausea/Vomiting (PONV), safety of intraluminal injection of high concentration alkalinized local anaesthetic solution by comparing adverse events between placebo and treatment arms. In addition, rehospitalisation rates and postoperative length of stay will be compared between the three groups. Population: 150 adult patients undergoing ureteroscopy for ureteric stone disease stratified into negative ureteroscopy and those treated for a stone with or without stent insertion postoperatively Number of Sites: Tallaght Hospital Study Duration: 8 months

NCT ID: NCT03285334 Not yet recruiting - Postoperative Pain Clinical Trials

3D Instrumentation Versus Rotary Instrumentation

Start date: November 2017
Phase: N/A
Study type: Interventional

enrollment of the patient after diagnosis, radiographic evaluation, and signing the informed consent. allocation of the patient to either intervention or control group. After anaesthesia and access cavity, the first root canal sample will be taken. Endodontic treatment will be completed in one visit. The second root canal sample will be taken. Patients will be asked to evaluate their postoperative pain level using VAS scale at 6, 12, 24 hours, and daily up to 5 days. Patients will record the number of analgesics if any taken.

NCT ID: NCT03275207 Not yet recruiting - Clinical trials for Chronic Postoperative Pain

Dexmedetomidine for Prevention of Chronic Postoperative Pain

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

Chronic postoperative pain (CPSP) is common symptom in patients after surgery, seriously affected the quality of life. Accumulating evidences have demonstrated dexmedetomidine can improve chronic pain. However, the prevention of dexmedetomidine on CPSP remain uncertain.

NCT ID: NCT03252301 Not yet recruiting - Pain, Postoperative Clinical Trials

Assessment of Pain in Surgical Patient by PMD 200

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

The trial will estimate post-operative pain management in elective surgical patients using the PMD-200 device. The device measures physiological parameters by placing a non-invasive sensor on a fingertip and displays an objective pain level in a 0-100 scale. The pain level will be estimated before surgery (baseline), after surgery and during administration of parenteral analgesia. Treatment and analgesia will be given according to clinical considerations and standard ward protocols. The device measurements won't influence the treatment.

NCT ID: NCT03199482 Not yet recruiting - Postoperative Pain Clinical Trials

Effect of Pretreatment Dexamethazone on Pain and Success of Nerve Block

Start date: July 12, 2017
Phase: Early Phase 1
Study type: Interventional

A Comparative Evaluation of the effect of pretreatment dexamethasone versus placebo on post-endodontic pain and success of inferior alveolar nerve block in Mandibular molars with symptomatic Irreversible Pulpitis: A Blinded Randomized Clinical Trial Therapeutic study

NCT ID: NCT03189771 Not yet recruiting - Clinical trials for Apical Periodontitis

Effect of Occlusal Reduction on Post-operative Pain

Start date: June 27, 2017
Phase: N/A
Study type: Interventional

effect of occlusal reduction on post-operative pain is evaluated after single visit root canal treatment in upper and lower molar teeth in patients with sypmtomatic irreversible pulpitis and apical periondontis

NCT ID: NCT03176758 Not yet recruiting - Clinical trials for Total Knee Replacement Surgery

Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia

Start date: June 1, 2017
Phase: Phase 4
Study type: Interventional

Total knee arthroplasty may be conducted either under general anesthesia or spinal block. previous studies have shown that spinal block leads to less complications. The investigators aim to find whether post-operative pain is also diminished under spinal block compared to general anesthesia

NCT ID: NCT03137732 Not yet recruiting - Pain, Postoperative Clinical Trials

Surgical Versus Anaesthetic Placement of Rectus Sheath Catheters

SPARC
Start date: June 2017
Phase: N/A
Study type: Interventional

This is a single centred randomized controlled trial comparing surgeon versus anaesthetist inserted rectus sheath catheters for management of analgesia post major abdominal surgery.

NCT ID: NCT03128346 Not yet recruiting - Postoperative Pain Clinical Trials

Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

The TTP block is a novel regional anesthetic technique that shows promise in providing analgesia for anterior chest wall incisions and median sternotomy. The investigators hope to show that by providing the TTP block, there will be reduced early postoperative pain, reduced sedation and shallow breathing, reduced time on breathing machine, leading to an increase in patient comfort and satisfaction. The investigators also hope the decreased need for pain medication and reduced time on the breathing machine will translate into decreased nursing workload.