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Pain, Postoperative clinical trials

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NCT ID: NCT03080272 Completed - Pain, Postoperative Clinical Trials

Do we Achieve the Goal of "No Worse Than Mild Pain" in Daily Clinical Practice?

Start date: March 3, 2017
Phase:
Study type: Observational

With this study the investigators want to perform a prospective cross-sectional audit at Zealand University Hospital, Koege, Denmark. The aim is to investigate the actual pain treatment and outcomes from a representative number of surgical procedures from different surgical departments.

NCT ID: NCT03079830 Completed - Clinical trials for Aortic Valve Surgery

Postoperative Pain Management After Minimally Invasive Aortic Valve Surgery

PPMAMIAVS
Start date: October 2016
Phase: N/A
Study type: Interventional

The study evaluates the efficacy of local anesthestic application through the catheter in the surgical wound for the postoperative pain relief after minimally invasive aortic valve surgery. The patients will be enrolled in two different groups according to the protocol of the local anesthetic and saline administration: 1. group: continous infusion of the local anesthetic plus bolus on demand 2. group: continous infusion of saline plus bolus on demand For all patients metamizol every 12 hours plus bolous of piritramid on demand.

NCT ID: NCT03079076 Completed - Pain, Postoperative Clinical Trials

Ultrasound Guided Modified Thoracolumbar Interfascial Plane Block for Spinal Surgery

TLIP
Start date: March 15, 2017
Phase: Phase 4
Study type: Interventional

Ultrasound guided thoracolumbar interfascial plane (TLIP) block was first described in 2015 by Hand et al. TLIP block involves injection of local anesthetics between multifidus and longissimus muscles at the third lumbar vertebra level and can block the dorsal rami of thoracolumbar nerves. In new approach differently, the investigators made the injection between longissimus and iliocostalis muscles with a 15 degree angle from medial to lateral. The aim of this study is to determine effectiveness of ultrasound guided thoracolumbar interfascial plane (TLIP) block in patients undergoing spinal surgery.

NCT ID: NCT03076710 Withdrawn - Analgesia Clinical Trials

Post-Operative Pain Management Following Spine Surgery

EXPAREL
Start date: July 31, 2017
Phase:
Study type: Observational

The primary objective of this pilot study is to assess the feasibility of comparing two standardized approaches to manage post-operative pain following spine surgery: one approach using Patient Controlled Analgesia (PCA) devices to deliver opioid analgesics, and the other approach using EXPAREL® infiltration at the site of surgery and nurse-administered opioid analgesics.

NCT ID: NCT03074097 Completed - Postoperative Pain Clinical Trials

Rectus Sheath Block: Postoperative Analgesia and Proinflammatory Cytokines

Start date: March 5, 2015
Phase: Phase 2
Study type: Interventional

Good quality of postoperative analgesia would lead to attenuate or prevent the adverse effects on the common functions of the immune system. We compared the effect of epidural analgesia versus rectus sheath block on postoperative pain and proinflammatory cytokines following malignant urological surgery.

NCT ID: NCT03073980 Completed - Pain, Postoperative Clinical Trials

Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval

Start date: September 1, 2019
Phase: Phase 4
Study type: Interventional

In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge from the hospital. We will compare three types of pre-operative medications: intravenous (IV) acetaminophen, oral (PO) acetaminophen, and placebo (no medication), which is the current typical care.

NCT ID: NCT03071991 Recruiting - Pain, Postoperative Clinical Trials

Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement

Start date: January 2017
Phase: N/A
Study type: Observational

Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort. We believe that preincisional bupivacain injection to the trocar sites will help us for these problems. A study is designed focused on reduced postoperative pain and reduced use of narcotic analgesics by preincisional bupivacain injection for laparoscopic bariatric patients.

NCT ID: NCT03071185 Recruiting - Clinical trials for Pain, Post Operative

The Efficacy and Safety of Lower Limb Nerve Blocks in Postoperative Analgesia for the Free Flap Donor Sites

Start date: January 20, 2017
Phase: N/A
Study type: Interventional

The use of free fibular flaps and anterolateral thigh (ALT) flaps for repairing the oromandibular defects is well established, whereas few attentions were focused on postoperative analgesia for the donor area. Dexmedetomidine is a more selective and shorter-acting α2 adrenergic receptor. The purpose of this trial is to determine if using lower limb nerve blocks in patients undergoing free flap-based oromandibular reconstruction can significantly decrease use of pain medications and to evaluate the safety of lower limb nerve blocks. We also investigated the effect of adding dexmedetomidine as additive in femoral nerve blocks for postoperative analgesia. Patients with oromandibular defects who were scheduled for elective reconstructive surgery using free fibular or ALT flaps, were divided into three groups in a randomized, single-blind fashion. In Group PCA, only intravenous patient controlled analgesia (PCA) was used postoperatively. In Group PCA+B, both intravenous PCA and lower limb blocks were used. In Group PCA+B+D, both intravenous PCA and lower limb blocks with dexmedetomidine as additivewere used. Post-operative narcotic usage, post-operative pain score, post-operative anti-emetic usage, vital signs, onset and duration of sensory and motor block, the presence of adverse effects such as nausea and vomiting were recorded.

NCT ID: NCT03069586 Recruiting - Postoperative Pain Clinical Trials

Effect Low Pressure Pneumoperitoneum and Pulmonary Recruitment on Postoperative Pain

Start date: May 2015
Phase: N/A
Study type: Interventional

The investigators want to test the hypothesis that the addition of a recruitment manoeuvre to a low pressure pneumoperitoneum will lead to an additional reduction in postoperative pain. Therefore the investigators will conduct a prospective randomized controlled, single blind trial.

NCT ID: NCT03068260 Completed - Postoperative Pain Clinical Trials

Ultrasound-guided Transmuscular Quadratus Lumborum Block for Elective Caesarean Section.

Start date: March 15, 2017
Phase: Phase 4
Study type: Interventional

ECS is a very common procedure. A 1-year retrospective survey revealed a vast opioid consumption among the new mothers of approximately (mean±SD) 35±25 mg of oral morphine in the first 24 postoperative hours despite a multimodal analgesic regimen. The adverse effects of morphine are well known and include postoperative nausea and vomiting (PONV), itching, fatigue, constipation, confusion, respiratory depression and delayed mobilization. These adverse effects are unsound for the new mothers as well as the breast-fed, newborn children. This study aims to evaluate the efficacy of bilateral Transmuscular Quadratus Lumborum (TQL) block in reducing postoperative morphine consumption and pain.