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Pain, Postoperative clinical trials

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NCT ID: NCT04333992 Completed - Postoperative Pain Clinical Trials

Propofol Versus Sevoflurane on Acute Postoperative Pain

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

This study was performed to compare the acute postoperative pain intensity and opioid consumption after total shoulder arthroplasty between propofol-remifentanil and sevoflurane-remifentanil anesthesia.

NCT ID: NCT04333095 Recruiting - Pain, Postoperative Clinical Trials

Sternal Block With Liposomal Bupivacaine vs. Saline Prior to Incision in Cardiac Surgery

Start date: February 6, 2020
Phase: Phase 4
Study type: Interventional

The purpose of this study is to find out what effects (good and bad) that the study medicine called "liposomal bupivacaine" has on subjects that are undergoing a sternotomy. Liposomal bupivacaine solution, is a drug that the doctor will inject before they make the cut through patient's breastbone (sternotomy). Normally pain medicine like this is given right before the surgeon closes up the patient's breastbone, at the end of the surgery. For this study, they want to see if giving the medicine before they make the cut into the patient's breastbone helps their pain. They also want to find out if patients feel less pain after surgery with the study drug than they do with saline and possibly decrease the need for pain medicine. Subjects will be in the study for about 72 hours or until they are discharged from the hospital.

NCT ID: NCT04327453 Recruiting - Clinical trials for Effects of the Elements

Effect of Removal of Double Antibiotic Paste on Post Operative Pain

Start date: April 2020
Phase: N/A
Study type: Interventional

Recruited patients with necrotic pulp after application of double antibiotic paste are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side vented needle) to remove intracanal medication and record postoperative pain afterwards.

NCT ID: NCT04326998 Completed - Postoperative Pain Clinical Trials

Gutta-percha Solvent on Postoperative Pain After Root Canal Retreatment

Start date: September 18, 2019
Phase: N/A
Study type: Interventional

The process of non-surgical retreatment includes removing the previous root canal filling materials, disinfecting and sealing the root canal system to prevent re-infection. Gutta-percha is the most common root canal filling material used with various types of sealers. To remove gutta-percha, solvent has been suggested because of its ability to dissolve gutta-percha. The new formula, under the brand name, GuttaClear, has been investigated for its comparable dissolving ability and lower cytotoxicity when compared with others that are currently used. However, no information is currently available of GuttaClear solvent concerning postoperative pain. Therefore, the present study will evaluate postoperative pain after non-surgical retreatment cases using GuttaClear as a solvent compared with no solvent used. Sixty participants are chosen and distributed into 2 groups, randomly. After the procedures, participants will receive the questionnaires about postoperative pain and the amount of medication intake. Both will be recorded at six time periods: (1) immediately after procedure; (2) 6 hours after procedure; (3) 12 hours after procedure; (4) 24 hours after procedure; (5) 48 hours after procedure and (6) 72 hours after procedure.

NCT ID: NCT04325984 Completed - Postoperative Pain Clinical Trials

Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery

Start date: August 29, 2017
Phase:
Study type: Observational

The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patients who underwent lobectomy, segmentectomy or atypical resection surgery with a mini-thoracotomy approach or video-assisted thoracoscopic surgery (VATS).

NCT ID: NCT04324086 Recruiting - Clinical trials for Effects of the Elements

Effect of Removal of Intracanal Medication on Post Operative Pain

Start date: April 1, 2020
Phase: N/A
Study type: Interventional

Recruited patients with necrotic pulp after application of Calcium hydroxide are assigned to group (XP Endo Finisher file) and group( Passive ultrasonic irrigation) and group (conventional syringe irrigation with side vented needle) to remove intracanal medication and record postoperative pain afterwards.

NCT ID: NCT04319549 Not yet recruiting - Clinical trials for Acute Irreversible Pulpitis With Apical Periodontitis

Ketorolac Irrigant on Post Operative Pain

Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Endodontic post-treatment pain management is one of the most challenging problems in the clinical practice of endodontics. Although this pain is decreased after root canal treatment, there may be residual symptoms due to inflammation. It has been reported that up to 80% of patients with preoperative pain, will report pain after endodontic treatment, which might range from mild to severe. Management of endodontic pain should involve all steps of treatment including preoperative pain control through accurate diagnosis and reduction of anxiety, intraoperative pain control through effective and profound local anesthetic, operative techniques and that can be achieved through a variety of pharmacologic agents. Many mechanisms have been proposed to explain the reason for postoperative pain including the sensitization of nociceptors by inflammatory mediators. Among these chemical inflammatory mediators are the prostaglandins which is the terminal product of arachidonic acid metabolism, through the cyclooxygenase (COX) pathway. Endodontic treatment can cause the release of inflammatory mediators (e.g. prostaglandins, leukotrienes, bradykinin, platelet- activating factor and substance P) into the surrounding periapical tissues, causing pain fibers to be directly stimulated (by bradykinin for instance) or sensitized (by prostaglandins). In addition, the vascular dilation and increased permeability as a consequence of periradicular inflammation, cause edema and increased interstitial tissue response. Single-visit root canal treatment is common in some endodontic practices. However, one of the main concerns with this approach has been the fear of post- operative pain. Mechanical, chemical and microbiological injuries to the peri- radicular tissues during root canal treatment have been suggested as possible causes of post-operative pain. The role of irrigating solutions used during root canal treatment to help control post-operative pain is unclear. While certain studies have observed a reduction in post-operative pain with particular types and concentrations of irrigating solutions, other studies have reported no difference in post-operative pain with the different irrigating solutions .

NCT ID: NCT04318860 Completed - Postoperative Pain Clinical Trials

Postoperative Pain After Colorectal Surgery

Start date: March 15, 2013
Phase:
Study type: Observational

This study aimed to evaluate pain after elective colorectal surgery and to identify risk factors for postoperative pain. Patients:All elective colorectal surgeries at the department of surgery, Umeå university Hospital, Umeå, Sweden from March 2013 to April 2017 Primary outcome:The primary outcome measurement is the numeric rating scale (NRS), graded from 0-10, on day of surgery, postoperative (POD) 1, 2, 3. The patients are questioned by nurses each morning on four postoperative days to score the maximum pain during the previous 24 hours using the NRS.

NCT ID: NCT04316416 Completed - Postoperative Pain Clinical Trials

Evaluation of Effectivity of Erector Spina Plane Block With Different Levels

Start date: February 15, 2020
Phase: N/A
Study type: Interventional

In last years, erector spinae plane block is widely used in abdominal and thoracic surgeries. Laparoscopic cholecystectomy is one of the most commonly performed surgical operations. In this study, the investigators will evaluate the effectiveness of erector spina plan block with different injection levels for postoperative analgesia on patients undergoing laparoscopic cholecystectomy surgery.

NCT ID: NCT04314908 Not yet recruiting - Postoperative Pain Clinical Trials

"Effect of Sonic Activation Assisted Irrigation and Apical Enlargement on Postoperative Endodontic Pain"

Start date: June 10, 2020
Phase: N/A
Study type: Interventional

The purpose of this randomized clinical trial is to evaluate the incidence of postoperative pain after retreatment after apical enlargement and sonic activation assisted irrigation. The presence of postoperative pain will assess after retreatment cases at 12, 24, 48, 72 hrs and 1 week.