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Pain, Postoperative clinical trials

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NCT ID: NCT05784493 Completed - Postoperative Pain Clinical Trials

Pain After Laparoscopic Hysterectomy

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

The investigators evaluated postoperative pain after total laparoscopic hysterectomy. Two arm are evaluated. During laparoscopic hysterectomy, in one arm; abdominal cavity was washed by saline at normal room temperature. In another arm; abdominal cavity was washed heated saline . Postoperative pain was evaluated by using visual analogy scale.

NCT ID: NCT05783011 Completed - Periodontitis Clinical Trials

The Effects of Electroacupuncture on Postoperative Pain

Start date: March 30, 2021
Phase: N/A
Study type: Interventional

In this study,the investigators aimed to examine the effect of electroacupuncture application on the amount of pain felt by patients after periodontal surgery. The main question it aims to answer is there any efficiacy of electroacupuncture application on postoperative pain reduction. Participants will get periodontal flap surgery treatment with/without electroacupuncture Researchers will compare EA and control groups to see if there is any relationship between acupuncture application and postoperative pain

NCT ID: NCT05782608 Completed - Colorectal Cancer Clinical Trials

IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese Patient

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to assess the Efficacy of IV Ibuprofen and Ketorolac in the Management of Postoperative Pain in obese patients Following abdominal cancer surgery.

NCT ID: NCT05774249 Completed - Postoperative Pain Clinical Trials

Pecto-intercostal Fascial Plane Block for Postoperative Analgesia and Recovery Profile After Off-Pump Coronary Artery Bypass Surgery

Start date: March 20, 2023
Phase: N/A
Study type: Interventional

Moderate to severe postoperative pain is usually encountered after cardiac surgery.Improper postoperative pain control could have multiple hemodynamic hazards in addition to prolonged postoperative ventilatory support and intensive care unit stay .The safety and efficacy of ultrasound guided chest wall plane blocks has been described for postoperative analgesia after cardiac surgeries. Study objective: to investigate the effect of adding of pecto-intercostal fascial plane block on the postoperative pain control, perioperative analgesic consumptions and the time for ventilation weaning and intensive care unit discharge in patients who will undergo off-pump Coronary artery bypass surgeries. Methods: This study patients will be randomly assigned to 2 Groups to receive preoperative ultrasound-guided pecto-intercostal fascial plane block with either 20 mL of 0.25% bupivacaine with adrenaline 1:400,000 or saline bilaterally.

NCT ID: NCT05772832 Completed - Postoperative Pain Clinical Trials

COMPARISON OF DEXMEDETOMIDINE AND REMIFENTANIL FOR POSTOPERATIVE PAIN IN TRANSPHENOIDAL Pituitary SURGERY

Start date: November 17, 2021
Phase:
Study type: Observational [Patient Registry]

In patients with pituitary adenoma scheduled for endoscopic transsphenoidal pituitary surgery, it was aimed to compare the efficacy of postoperative pain relief of a selective α-2 agonist "Dexmedetomidine" and the rapid and short-acting opioid "Remifentanil" using the "Numerical Rating Scale" (NRS) administered alongside propofol in perioperative maintenance anesthesia. .

NCT ID: NCT05769855 Completed - Clinical trials for Postsurgical Pain Management

A Study of HR18034 for Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy

Start date: March 21, 2023
Phase: Phase 3
Study type: Interventional

The study is being conducted to evaluate the efficacy, and safety of HR18034 for postoperative analgesia in subjects undergoing hemorrhoidectomy.

NCT ID: NCT05769309 Completed - Postoperative Pain Clinical Trials

Efficacy of Erector Spinae Plane Block Analgesia After Off Pump Cardiac Surgery

ESPB
Start date: March 22, 2023
Phase: N/A
Study type: Interventional

In this study the investigators will investigate the efficacy of ESPB as a part of Enhanced recovery after surgery on postoperative analgesia and recovery criteria after off pump cardiac surgery.

NCT ID: NCT05765318 Completed - Postoperative Pain Clinical Trials

Quadratus Lumborum Block for Total Abdominal Hysterectomy

Start date: February 27, 2023
Phase: N/A
Study type: Interventional

Procedure specific postoperative pain management (PROSPECT) guidelines for abdominal hysterectomy published in 2006 recommended laparoscopic or vaginal hysterectomy as a preferred surgical technique. Multimodal postoperative pain management plane includes cyclooxygenase-2 (COX-2) selective inhibitors, and/or conventional non-steroidal antiinflammatory drugs (NSAID) in combination with strong opioids for high-intensity pain or with weak opioids for moderate- or low-intensity pain. Paracetamol also was recommended in combination with COX-2 inhibitors or conventional NSAIDs. Epidural analgesia was recommended for high-risk patients. PROSPECT guidelines updated in 2018 discuss only perioperative approach for laparoscopic hysterectomy. However, hysterectomy technique has been switched from total abdominal to laparoscopic approach. In low resources settings, laparoscopic technique is nor well developed neither available to many patients. Furthermore, the majority of patients undergo total abdominal hysterectomy (TAH), that is very painful procedure. Quadratus lumborum block (QLB) is a regional analgesic technique described by Blanco in 2007. Society for Obstetric Anesthesiology and Perinatology (SOAP) and European Society for Regional Anaesthesia and Pain Therapy (ESRA) recommended QLB for post-Cesarean pain management in cases where intrathecal morphine could not be used or for breakthrough pain. Previous reports have shown that QLB is effective in providing pain relief after various abdominal operations. The effects of QLB for laparoscopic hysterectomy is controversial. We would like to see if QLB can provide analgesic benefits in multimodal pain management after TAH in our clinical settings.

NCT ID: NCT05764525 Completed - Pain, Postoperative Clinical Trials

Phase 3 Efficacy and Safety of VVZ-149 Injections for Postoperative Pain Following Laparoscopic Colectomy

Start date: July 19, 2021
Phase: Phase 3
Study type: Interventional

The purpose of this phase 3 study is to evaluate the efficacy and safety of VVZ-149 Injections for the treatment of postoperative pain following laparoscopic colectomy.

NCT ID: NCT05758090 Completed - Analgesia Clinical Trials

Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years

Start date: March 10, 2023
Phase: N/A
Study type: Interventional

During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist. There are some monitors, e.g., Analgesia Nociception Index (ANI), showing that they can evaluate analgesia in adults. Recently, a Newborn Infant Parasympathetic Evaluation (NIPE) monitor was released for assessing analgesia in children with age less than 2 years. The investigators aim to assess the efficacy of NIPE as a guide for intraoperative fentanyl administration in children under 2 years.