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Pain, Postoperative clinical trials

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NCT ID: NCT04709211 Completed - Postoperative Pain Clinical Trials

Fascia Iliaca Compartment Block Versus Anterior Quadratus Lumborum Block

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

Fractures of the femur are common orthopaedic emergency especially in the geriatric population and central neuraxial blocks are the preferred technique for providing anaesthesia. However, limb immobility and extreme pain are the deterrents for ideal positioning for these procedures. postoperative pain is a nightmare so adequate analgesia has been advocated to reduce the pain. in this study, Facia Iliaca compartment block will be compared to anterior Quadratus lumborum block, both will be done Ultrasound-guided using Bupivacain0.25% for postoperative analgesia at the end of the surgery.

NCT ID: NCT04708353 Recruiting - Gynecologic Disease Clinical Trials

Oral Pregabalin Premedication for Postoperative Pain Relief

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

Pain management after gynecological surgeries is essential for early mobilization of the patient, decrease postoperative complication and hospital stay. The use of opioids is associated with adverse effects such as nausea, vomiting, ileus, pruritus, sedation and respiratory depression. Previous studies stated that pregabalin has been used to reduce pre-operative anxiety, acute postoperative pain, postoperative opioid requirements, postoperative nausea, vomiting and postoperative delirium. The most effective dose of pregabalin to relief postoperative pain with least side effect is still under trial. In this study we will compare between two different doses of pregabalin when given as oral premedication in patients undergoing gynecological surgeries under spinal anesthesia regarding postoperative pain in order to reduce opioids consumption and subsequently avoid opioid-related adverse effects.

NCT ID: NCT04705311 Completed - Pain, Postoperative Clinical Trials

The Effect of Pain Neuroscience Education on Patients With Arthroscopic Rotator Cuff Repair

Start date: February 10, 2021
Phase: N/A
Study type: Interventional

During the rehabilitation process after rotator cuff repair surgery, patients suffer from increased pain and discomfort due to dysfunction. Pain neuroscience education, a more modern educational method, has been reported to be effective in controlling pain by reducing the fear of movement based on an understanding of neurophysiology.

NCT ID: NCT04703257 Completed - Surgery Clinical Trials

Evaluation of the Added Value of Metamizole to Standard Postoperative Treatment After Ambulant Shoulder Surgery

Metamizole003
Start date: February 26, 2021
Phase: N/A
Study type: Interventional

This study aims to investigate if the combination of metamizole and paracetamol is superior in reducing post-operative pain on day 1 after ambulatory shoulder surgery where the use of NSAIDs is prohibited compared to paracetamol treatment. Therefore, a monocenter, prospective, double-blind, randomized controlled superiority trial will be designed to investigate the superiority of the combination of metamizole and paracetamol compared to paracetamol treatment in patients undergoing arthroscopic shoulder surgery with tendon repair.

NCT ID: NCT04702685 Not yet recruiting - Pain, Postoperative Clinical Trials

Erector Spinae Plane Block With Ropivacaine for Major Upper Abdominal Surgery

Start date: January 2021
Phase: Phase 3
Study type: Interventional

Prospective, single-centre, randomized, controlled, open-label, evaluator-blinded, superiority trial.

NCT ID: NCT04702061 Completed - Pain, Postoperative Clinical Trials

Comparison of Erector Spina Plane Block and Thoracic Epidural Block

Start date: January 11, 2021
Phase: N/A
Study type: Interventional

The aim of this randomised controlled and double-blind study, is to compare the effects of erector spinae plane (ESP) and thoracic epidural (TEA) blocks on peri-operative hemodynamics and analgesia in patients undergoing unilateral mastectomies due to malignancy.

NCT ID: NCT04701008 Completed - Pain, Postoperative Clinical Trials

Efficacy of Ketamine in Post Anesthesia Recovery Room

Start date: September 1, 2020
Phase:
Study type: Observational

Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.

NCT ID: NCT04700995 Completed - Clinical trials for Apical Periodontitis

Postoperative Pain After Using NiTi Instruments

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

The aim of this randomized clinical trial was to compare the incidence, intensity and duration of postoperative pain following the removal of root canal obturation materials canals using rotary (ProTaper Universal or Hyflex EDM) or reciprocating file (Reciproc Blue or WaveOne Gold) systems. The null hypothesis tested was that there is no difference in postoperative pain following the retreatment procedure between the four systems used.

NCT ID: NCT04700228 Enrolling by invitation - Pain, Postoperative Clinical Trials

Comparison of Doses of Dexmedetomidine With Bupivacaine in Caudal Block for Duration of Analgesia in Paediatric Infraumblical Surgeries.

Start date: February 2021
Phase: Phase 4
Study type: Interventional

Various methods are used to control post-operative pain among children. Amongst these methods, caudal block is one of the most favoured, prominent and dependable methods for providing reliable analgesia in surgeries below umbilicus. This study is to compare two doses of Dexmedetomidine added as adjunct to local anaesthesia using reduced dose in caudal block for prolonging the duration of analgesia. Our secondary outcomes will include blood pressure, heart rate, urinary retention, nausea and vomiting in the paediatric population.

NCT ID: NCT04699175 Active, not recruiting - Clinical trials for Postsurgical Pain Management

A Trial of HR021618 in Postsurgical Pain Management

Start date: December 17, 2020
Phase: Phase 2
Study type: Interventional

The study is being conducted to evaluate the efficacy, safety of HR021618 and to explore the reasonable dosage of HR021618 for Pain Management after Orthopaedic surgery.