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Pain, Postoperative clinical trials

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NCT ID: NCT03341533 Completed - Pain, Postoperative Clinical Trials

Abdominal Ice Packs for Pain Control and Reduction of Narcotic Use Following Laparoscopic Hysterectomy

Start date: January 12, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of using ice packs on the abdomen immediately after laparoscopic hysterectomy surgery on pain control and narcotic pain medication use.

NCT ID: NCT03341234 Completed - Pain, Postoperative Clinical Trials

Superficial Serratus Plane Block for Modified Radical Mastectomy and Axillary Lymph Node Disection

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

Breast cancer is the most common type of cancer in women. Mastectomy and axillary lymph node disection are commonly performed as part of the cancer management. This surgery can cause significant postoperative pain. The serratus plane block (SPB) has been described for analgesia of the hemithorax and reported for many cases such as thoracoscopy, shoulder arthroscopy, breast surgery and axillary lymph node dissections. Serratus plane block may be a viable alternative to current regional anaesthetic techniques such as thoracic paravertebral and central neuraxial blockade. The aim of this study is to determine effectiveness of ultrasound guided superficial serratus plane block in patients undergoing modified radical mastectomy and axillary lymph node dissection surgery.

NCT ID: NCT03332316 Completed - Postoperative Pain Clinical Trials

Effect of Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Ankle Surgery

Start date: November 2, 2017
Phase: Phase 4
Study type: Interventional

Effect of perineural dexamethasone on the duration of popliteal nerve block after ankle/foot surgery

NCT ID: NCT03331588 Completed - Clinical trials for Carcinoma, Non-Small-Cell Lung

Comparison of Post-operative Pain and Quality of Life Between Subxiphoid and Intercostal VATS for Lung Cancer

Start date: November 10, 2017
Phase: Phase 3
Study type: Interventional

One-thirds of patients underwent video-assisted thorascopic surgery (VATS) still have severe pain.Uniportal lobectomy or segmentectomies emerged as a promising and exciting approach for minimally invasive thoracic surgery. However, nearly all reported uniportal VATS lobectomies have been performed via the intercostal route, and chest wall trauma has still occurred. Here,the investigators undertook novel uniportal VATS technique involving a subxiphoid route for pulmonary lobectomies or segmentectomies.We would like to evaluate the post-operative pain and quality of life between Subxiphoid and Intercostal VATS for Lung Cancer.

NCT ID: NCT03331315 Completed - Pain, Postoperative Clinical Trials

Toradol v. Celecoxib for Postoperative Pain

POP
Start date: September 1, 2013
Phase: Phase 2
Study type: Interventional

Randomized control trial between ketorolac versus celecoxib for postoperative pain following hysterectomy.

NCT ID: NCT03328988 Completed - Postoperative Pain Clinical Trials

QLB and Radical Cystectomy, Postoperative Pain

BladderQLB
Start date: April 27, 2017
Phase: N/A
Study type: Interventional

There are ca 1000 new cases of bladder cancer in Finland/year. The curative therapy for high risk bladder cancer is radical cystectomy. The golden standard is still an open surgery despite development of laparoscopic techniques. Epidural analgesia is considered as most effective for the treatment of postoperative pain. However, there is a need for other effective options, because epidural analgesia has some contraindications and risks for serious complications. Recently quadratus lumborum block has gained popularity in the treatment of postoperative pain after various surgeries in the area from hip to mamilla. It is more beneficial than other peripheral blocks, since it covers also the visceral nerves. Contrary to the need of epidural catether a single shot QLB has reported to last up to 48 hours. Inadequately treated acute postoperative pain is considered as one of the main risk factors for persistent postoperative pain. 44 patients aging 18-85 will be recruited based on a power calculation. The primary outcome measure is the acute postoperative need for rescue analgesics. Secondary outcomes are acute pain (NRS scale), nausea, vomiting, mobilisation and longterm outcomes such as quality of life and persistent pain.

NCT ID: NCT03328299 Completed - Postoperative Pain Clinical Trials

Pharmacokinetics and Dynamics of Dexmedetomidine as Adjuvant in TAP Block

Start date: November 11, 2017
Phase: Phase 2/Phase 3
Study type: Interventional

TAP-block has been shown to be a safe and effective postoperative analgesia method in a variety of general. Dexmedetomidine is a selective α2 agonist with 8 times more affinity for α2 adrenergic receptors compared to clonidine and possesses all the properties of α2 agonist without respiratory depression. Dexmedetomidine has been focus of interest for its broad spectrum (sedative, analgesic and anesthetic sparing) properties, making it a useful and safe adjunct in many clinical applications.

NCT ID: NCT03323385 Completed - Pain, Postoperative Clinical Trials

Evaluation of Preoperative N1539 in Colorectal Surgery

Start date: October 24, 2017
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the safety and tolerability of preoperative dosing of N1539 30 mg in subjects undergoing colorectal surgery, including clinical laboratory tests, wound healing evaluation, incidence of anastomotic leaks, and incidence of Adverse Events (AEs) and Serious AEs (SAEs).

NCT ID: NCT03319277 Completed - Postoperative Pain Clinical Trials

A Randomized-controlled Trial of Post-operative Opiate Quantities After Urogynecologic Surgery

Start date: October 13, 2017
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to determine the effect of decreased post-operative prescriptions of opiate medications after urogynecologic surgery.

NCT ID: NCT03315481 Completed - Pain Clinical Trials

Ultrasound Guided Repositioning of a New Suture‐Method Catheter for Adductor Canal Block

Start date: March 7, 2017
Phase: N/A
Study type: Interventional

This is a randomized clinical trial in healthy volunteers. 12 volunteers will have suture-method catheters placed in the adductor canal of each leg using the long-axis plane and short-axis plane technique. The investigators will inject LA in both catheters to confirm correct position. Following return of cold sensation the catheter is then displaced intentionally. The orifice is identified by injection of isotonic saline to ensure a proper displacement (spread outside of the adductor canal) and the distance from the delivery orifice of the catheter to the adductor canal is noted. A second investigator will assess distance from the LA delivery orifice of the catheter to the adductor canal using hydrodissection with isotonic saline to pinpoint the delivery orifice and subsequently reposition the catheter to obtain LA spread within the adductor canal. Successful repositioning is defined as a combination of LA spread within the adductor canal and loss of cold sensation on the medial part of the lower leg.