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Osteoporosis clinical trials

View clinical trials related to Osteoporosis.

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NCT ID: NCT03811509 Recruiting - Osteoporosis Clinical Trials

Breast Cancer Women on Aromatase Inhibitors Treatment

B-ABLE
Start date: January 1, 2016
Phase: Phase 4
Study type: Interventional

The main objective of the study is to improve the life quality of women treated with AI. Cohort B-ABLE is designed to evaluate musculoskeletal events derived of using AI in breast cancer women. The project objectives are the analysis of the AI deleterious effect on bone microarchitecture and early determination of the risk of fragility fracture with dual energy x-ray absorptiometry (DEXA), lumbar spine Rx, Trabecular Bone Score (TBS) and microindentation. Determination of physiological causes of the AI-related arthralgia by analyzing joint degradation markers, steroid hormone levels remaining in blood and functional magnetic resonance, before and after three months of AI treatment

NCT ID: NCT03798444 Completed - Clinical trials for Osteoporosis Fracture

Height Loss, Kyphosis Indicators, Bone Mineral Density and Vertebral Fractures in Chinese Postmenopausal Women

Start date: September 1, 2017
Phase:
Study type: Observational

This is an observational and cross-sectional study on the height loss, kyphosis indicators, bone mineral density and vertebral fractures in Chinese postmenopausal women

NCT ID: NCT03798418 Recruiting - Stroke Clinical Trials

Sarcopenia and Risk of Falls in Patients With Major Chronic Diseases

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to investigate the effects of therapeutic exercise and nutrition intervention for sarcopenia and risk of falls in patients with major chronic diseases. The outcomes will be analyzed regarding muscle strength, quality, and volume, etc., balance and gait, bone density, body composition, fall and quality of life after the intervention.

NCT ID: NCT03770338 Not yet recruiting - Osteoporosis Clinical Trials

Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without. The increased insertional torque of pedicle screws during surgery after only 1 month of teriparatide use has also been studied. However, the effect of teriparatide on vertebral body bone mineral density (BMD) prior to and after fusion surgery has not been studied. The effects on screw insertional torque has also not been studied via a randomized controlled trial method.

NCT ID: NCT03764462 Recruiting - Osteoporosis Clinical Trials

Evaluating the Pharmacokinetic Characteristics of AD-101 in Healthy Volunteers

Start date: November 30, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic characteristics of AD-101 in healthy volunteers

NCT ID: NCT03761979 Completed - Osteopenia Clinical Trials

Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults

Start date: March 9, 2017
Phase: N/A
Study type: Interventional

No clinical trials have evaluated strontium L-lactate (SrLac), the strontium salt of the L-enantiomer of lactic acid. Therefore, this clinical study was conducted to obtain general safety and pharmacokinetic (PK) information following acute oral intakes of three doses of SrLac by healthy adults. The data provided valuable comparisons with the pharmacokinetics of other strontium salts that are in clinical use and allowed determination of the dose of SrLac that will be useful for the management of bone health.neficial for the treatment of low bone density of osteoporosis and osteopenia.

NCT ID: NCT03755193 Recruiting - Osteoporosis Clinical Trials

Examination of Efficacy and Safety of Other Anti-Resorption Drugs After 2-year-Denosumab Therapy in Japanese Osteoporosis Patients

Start date: November 24, 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in Japanese osteoporosis patients after 2-year-denosumab therapy: SERM and eldecalcitol treatment for 24 months Bisphosphonates and eldecalcitol treatment for 24 months Eldecalcitol treatment for 24 months

NCT ID: NCT03747289 Recruiting - Osteoporosis Clinical Trials

Comparison of a Weight Bearing and a Non-weight Bearing Protocol on Osteoporotic Women With Chronic Low Back Pain

Start date: December 20, 2018
Phase: N/A
Study type: Interventional

The effect of exercising in different body positions on bone growth in osteoporotic women is known, but its effect on their function, low back pain, lumbar range of motion and quality of life remains unknown. Therefore, the investigators plan to make a comparison of the effect of a weight bearing protocol and a non-weight bearing protocol on osteoporotic women with chronic low back pain. 40 women with osteoporosis and low back pain will be divided into two groups. Each group will be given a specific exercise protocol, twice a week for four weeks, 45 minutes each time. The participants will be tested before starting the program, immediately after finishing it and again two months later. The tests will include filling out the Roland Morris Disability Questionnaire, the SF-36 quality of life Questionnaire, pain measurement by VAS (Visual Analogue Scale) and lumbar range of motion measurement by a digital Inclinometer. Statistical analysis will be made in order to compare the dependent variables between groups.

NCT ID: NCT03742362 Not yet recruiting - Clinical trials for Osteoporosis, Postmenopausal

MRI Study of the Distal Radius Bone Marrow Fat Fraction in Osteoporotic and Healthy Women

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to test whether the distal radius bone marrow show significant difference in the fat fraction in young women compared to post menopausal women with and without osteoporosis.

NCT ID: NCT03730207 Recruiting - Clinical trials for Pathological Fracture of Vertebra Due to Secondary Osteoporosis (Disorder)

Xpede Clinical Study

Start date: December 18, 2018
Phase: N/A
Study type: Interventional

The purpose of this clinical study is to confirm the efficacy and safety of the Kyphon®Xpede™ Bone Cement in human use in China.