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Osteoporosis clinical trials

View clinical trials related to Osteoporosis.

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NCT ID: NCT03513107 Recruiting - Osteoporosis Clinical Trials

Osteoporosis Screening Tools' Re-validation in Egypt Guide for the Management of the Condition in Males

Start date: January 15, 2018
Phase:
Study type: Observational [Patient Registry]

To demonstrate the predictive ability of the different screening scores (i.e. OST, ORAI, ABONE, body weight criterion, age alone or others) and their potential use in the primary care setting.

NCT ID: NCT03512262 Recruiting - Osteoporosis Clinical Trials

Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM)

Start date: March 30, 2018
Phase: Phase 3
Study type: Interventional

A 12 month study to measure the efficacy and safety of abaloparatide in men with osteoporosis.

NCT ID: NCT03484208 Recruiting - Clinical trials for Osteoporotic Fractures

Evaluation of a Fracture Liaison Service in the Osteoporosis Care

Start date: February 8, 2018
Phase:
Study type: Observational

The St JOSEPH'S HOSPITAL set up a fracture liaison service for osteopotic fracture. A specific nurse screens eligible patient admitted in emergency yard and call them to propose a bone densitometry and a medical coverage.. The aim of the study is to evaluate this new organisation

NCT ID: NCT03472846 Recruiting - Clinical trials for Postmenopausal Osteoporosis

MiDeTe - microRNA Levels Under Denosumab and Teriparatide Therapy in Postmenopausal Osteoporosis

Start date: March 1, 2017
Phase: Phase 4
Study type: Interventional

The aim of this study is the quantitative determination of bone-specific microRNAs in the serum of postmenopausal women with osteoporosis during antiresorptive or osteoanabolic therapy.

NCT ID: NCT03467035 Recruiting - Clinical trials for Osteoporosis, Osteopenia

Role of NLRP3 Inflammasone and Hypoxia in the Severity of Osteoporosis in Patients With Bronchiectasis

Start date: December 21, 2017
Phase: N/A
Study type: Observational [Patient Registry]

The objectives of this research grant are to determine the association of hypoxia with the severity of osteoporosis in the patients with bronchiectasis and whether the mechanism of inflammation is triggered by inflammasones, which makes it more prone to osteoporosis in patients with bronchiectasis.

NCT ID: NCT03461237 Recruiting - Osteoporosis Clinical Trials

Chinese Second Hip Fracture Evaluation

CSHFE
Start date: May 1, 2017
Phase: N/A
Study type: Observational

1. To Compare overall rates of second hip fractures in both genders, 2. To determine the effect of hip fracture on proximal femoral volumetric bone mineral density (vBMD), bone structure and muscle by quantitative computed tomography(QCT), 3. To evaluate the contribution of QCT-image analysis to the prediction of the second hip fracture risk. 4. To identify the differences between femoral neck fracture and trochanter fracture following hip fracture

NCT ID: NCT03451305 Recruiting - Clinical trials for Osteoporosis Fracture

Postrual Reduction With Pillow in Osteoporotic Vertebral Fracture

Start date: January 23, 2018
Phase: N/A
Study type: Interventional

Vertebroplasty in the symptomatic osteoporotic vertebral fracture has become increasingly popular. However, there have been some limitations in restoring the height of the collapsed vertebrae and in preventing the leaking of cement. In the severely collapsed vertebrae of more than two thirds of their original height, vertebroplasty is regarded as a contraindication. We tried postural reduction using a soft pillow under the compressed level. This study was undertaken to investigate the effectiveness of the combination of postural reduction and vertebroplasty for re-expansion and stabilization of the osteoporotic vertebral fractures. single level vertebral compression fracture were treated with postural reduction followed by vertebroplasty. We analyzed the degree of re-expansion according to the onset duration.

NCT ID: NCT03437798 Recruiting - Diabetes Clinical Trials

Genomic Determinants and Shared Genetic Pathways of Periodontal Disease

Start date: January 30, 2018
Phase: N/A
Study type: Observational

Despite significant improvement in treating periodontal disease (PD) and the identification of multiple risk factors, little is known about the specific contribution of genetics to PD pathogenesis. Several genomewide association studies (GWAS) of PD have been published, but only one reported locus has reached the threshold for genome-wide significance. Epidemiological studies and biological experiments established associations and suggested common pathogenetic pathways between PD and cardiovascular disease (CVD), diabetes (DM), and osteoporosis. The overall objective is to identify genetic loci for PD as a first step toward a better understanding of PD pathogenesis. In a preliminary study in the Women's Genome Health Study (WGHS), new-onset cases of PD were associated with a family history of myocardial infarction (MI). Further preliminary analyses presented shared phenotypic variation of PD/CVD, PD/DM, or PD/osteoporosis that could be accounted by the whole-genome genetic matrices. Several variants from the GWAS catalog of bone density and family history of MI were found correlated with PD in the WGHS. Based on these findings and the literature, the central hypothesis is that there are common pathogenetic links between PD and these other diseases and that GWAS using the comorbidity case definitions will help identify potential common loci.

NCT ID: NCT03432533 Recruiting - Clinical trials for Post-Menopausal Osteoporosis

A Comparison of Subject-administered Romosozumab With Healthcare Provider-administered Romosozumab for Osteoporosis

Start date: February 6, 2018
Phase: Phase 3
Study type: Interventional

To evaluate the noninferiority of a 6-month treatment with 210 mg romosozumab at 90 mg/mL administered subcutaneously (SC) once a month (QM) in postmenopausal women with osteoporosis either by healthcare provider (HCP) administration with prefilled syringe (PFS) or by subject self-administration with autoinjector/pen (AI/Pen)

NCT ID: NCT03408119 Recruiting - Clinical trials for Osteoporosis, Osteopenia

Dried Plums Prevent Inflammation And Improve Bone Health in Osteopenic Men

Start date: November 20, 2017
Phase: N/A
Study type: Interventional

The goals of this study are 1) to investigate the extent to which dried plum improves bone health by measuring bone density (a measure of bone strength) of whole body, hip, and forearm, indicators of bone formation and bone breakdown, and 2) to determine the anti-inflammatory effects of dried plum by assessing biomarkers of inflammation. Additionally, relevant medical history and lifestyle variables will be recorded.