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Osteoporosis clinical trials

View clinical trials related to Osteoporosis.

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NCT ID: NCT03702140 Recruiting - Osteoporosis Clinical Trials

Examination How the Administration Period of Teriparatide Affects Bone Metabolism and Bone Mineral Density Prior to Denosumab Therapy

Start date: October 9, 2018
Phase: Phase 2
Study type: Interventional

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in osteoporosis patients: 1. The administration period of teriparatide is less than 6 months and thereafter, denosumab for 24 months. 2. The administration period of teriparatide is from 6 to 12 months and thereafter, denosumab for 24 months. 3. The administration period of teriparatide is more than 12 months and thereafter, denosumab for 24 months.

NCT ID: NCT03701113 Recruiting - Clinical trials for Osteoporosis, Postmenopausal

Milk Protein and Bone Health in Postmenopausal Women

Start date: October 22, 2018
Phase: N/A
Study type: Interventional

The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the life-cycle to effect net rate of formation (as occurs during growth and development to adulthood) or net resorption (as occurs, for example, during the menopause). Bone turnover is a nutritionally modulated process and the investigators believe a milk-based protein supplement (MBPS) can modulate beneficially the rate of bone resorption over the time period when bone remodeling is most active i.e. late evening/overnight. In this novel approach to the timing of nutrient ingestion, the proposed nutrient intervention seeks to modify (reduce) the rate of bone resorption and promote the rate of bone formation to the benefit of bone health in this at risk population..

NCT ID: NCT03699228 Recruiting - Obesity Clinical Trials

China Health Big Data

China biobank
Start date: December 1, 2017
Study type: Observational

In this nationwide multi center study the investigators combine the low dose chest CT scan data with QCT technology, to measure the BMD of spine, VAT and liver fat in the health check subjects. The aim of this study is to evaluate the performance of QCT in the health check field, and further to evaluate the prevalence of osteoporosis, obesity and liver steatosis in health check population across China.

NCT ID: NCT03648775 Recruiting - Osteoporosis Clinical Trials

Evaluation of the Clinical Efficacy of Y-STRUT® Medical Device Implanted for Contralateral Percutaneous Internal Fixation of Proximal Femur, in Patient With a Low Energy Per Trochanteric Fracture on the First Side

Start date: December 6, 2017
Study type: Observational

HIP50 is a national, multicentre, prospective, observational study, in patients presenting a first low energy per trochanteric hip fracture on one side and treated with Y-STRUT® device implanted on the contralateral proximal femur as percutaneous internal fixation to prevent contralateral hip fracture in case of osteoporosis. The primary objective of this study is to evaluate the clinical efficacy of the studied medical device by measuring the frequency of patient with a fracture at the implantation site within 1 year after implantation. A total of 50 patients from France will be enrolled (until December 2018) and followed up to 24 months.

NCT ID: NCT03605173 Recruiting - Osteoporosis Clinical Trials

Study on the Correlation of Free Vitamin d With BMD and Fracture

Start date: March 1, 2018
Phase: N/A
Study type: Interventional

According to the free hormone hypothesis, the biological activity of a hormone is carried by the portion that is not bound to protein or its carrier in circulation. Based on this, we believe that the free vitamin d, which is the proportion of Vitamin D unbound to vitamin D binding protein and albumin, performs the calcium-regulating functions of the vitamin. Hence, our objective is to study whether free vitamin correlated better with BMD and fracture than the total vitamin D.

NCT ID: NCT03600675 Recruiting - Osteoporosis Clinical Trials

Determinants of Bone Mineral Density and Metabolic Syndrome in South Asian Indian Men

Start date: May 8, 2015
Study type: Observational

This study aims to examine the association between body composition with bone density and risk factors for cardiovascular disease and type 2 diabetes. South Asian Indians have a lower bone density and a higher likelihood to develop metabolic syndrome (MetS) compared to Caucasians. MetS is a cluster of metabolic abnormalities that predispose an individual to cardiovascular disease and type 2 diabetes. This study will understand if the metabolic and biochemical markers ( Indicators of bone building and breaking in the blood and urine, Lipids and other proteins) explain both low BMD and MetS in SAI men

NCT ID: NCT03598556 Recruiting - Osteoporosis Clinical Trials

Preventing Bone Loss Among Chinese Patients With HIV on ART

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

The major goal of this study will be to conduct a randomized, double-blind, placebo-controlled, clinical trial of intermittent high-dose vitamin D3 supplementation (180,000IU) given at the point of care (every 3 months) after initiation of ART with tenofovir/ lamivudine/ efavirenz to compare its ability to mitigate reductions in bone mineral density over 12 months compared to placebo.

NCT ID: NCT03513107 Recruiting - Osteoporosis Clinical Trials

Osteoporosis Screening Tools' Re-validation in Egypt Guide for the Management of the Condition in Males

Start date: January 15, 2018
Study type: Observational [Patient Registry]

To demonstrate the predictive ability of the different screening scores (i.e. OST, ORAI, ABONE, body weight criterion, age alone or others) and their potential use in the primary care setting.

NCT ID: NCT03512262 Recruiting - Osteoporosis Clinical Trials

Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM)

Start date: March 30, 2018
Phase: Phase 3
Study type: Interventional

A 12 month study to measure the efficacy and safety of abaloparatide in men with osteoporosis.

NCT ID: NCT03484208 Recruiting - Clinical trials for Osteoporotic Fractures

Evaluation of a Fracture Liaison Service in the Osteoporosis Care

Start date: February 8, 2018
Study type: Observational

The St JOSEPH'S HOSPITAL set up a fracture liaison service for osteopotic fracture. A specific nurse screens eligible patient admitted in emergency yard and call them to propose a bone densitometry and a medical coverage.. The aim of the study is to evaluate this new organisation