Clinical Trials Logo

Osteoporosis clinical trials

View clinical trials related to Osteoporosis.

Filter by:
  • Not yet recruiting  
  • Page 1 ·  Next »

NCT ID: NCT03870100 Not yet recruiting - Osteoporosis Clinical Trials

The PK/PD Study of A Single Subcutaneous Injection of SHR-1222 in Healthy Subjects

Start date: March 20, 2019
Phase: Phase 1
Study type: Interventional

This is a Single Center, Randomized, Double-Blind, Dose Escalation, Placebo Parallel Controlled Phaseâ… Clinical study to Evaluate the Safety, Tolerability and Pharmacokinetics, Pharmacodynamics with A Single Subcutaneous Injection of SHR-1222 in Healthy Subjects. The primary objective of this study is to investigate the safety and tolerability of a range of subcutaneous SHR-1222 in healthy subjects. Secondary objectives are to determine the pharmacokinetics (PK) and pharmacodynamics(PD) profile of SHR-1222 in healthy subjects including assessment of immunogenicity.

NCT ID: NCT03824171 Not yet recruiting - Osteoporosis Clinical Trials

Evaluating the Pharmacokinetic Characteristics of AD-102 in Healthy Volunteers

Start date: February 1, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetic characteristics of AD-102 in healthy male subjects

NCT ID: NCT03811873 Not yet recruiting - Clinical trials for Metabolic Bone Disease

Assessment of Vertebral Fracture Risk for First Time Liver Transplant Candidates

Start date: January 28, 2019
Phase: N/A
Study type: Interventional

The Investigators hypothesize that VFA+ DXA is as effective in evaluation of asymptotic vertebral fractures compared to the current gold standard of spine x-ray. In addition, bone turnover markers in transplant patients are unknown. The investigators want to investigate bone turnover markers (Beta CTX and P1NP) as markers of bone health in patients listed for liver transplant.

NCT ID: NCT03770338 Not yet recruiting - Osteoporosis Clinical Trials

Preoperative Teriparatide Use on Insertional Torque of Pedicle Screws for Lumbar Fusion Surgery

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This project aims to investigate any difference of insertional torque strength for osteoporotic patients with preoperative 1-month teriparatide injections versus those without. The increased insertional torque of pedicle screws during surgery after only 1 month of teriparatide use has also been studied. However, the effect of teriparatide on vertebral body bone mineral density (BMD) prior to and after fusion surgery has not been studied. The effects on screw insertional torque has also not been studied via a randomized controlled trial method.

NCT ID: NCT03742362 Not yet recruiting - Clinical trials for Osteoporosis, Postmenopausal

MRI Study of the Distal Radius Bone Marrow Fat Fraction in Osteoporotic and Healthy Women

Start date: January 15, 2019
Phase: N/A
Study type: Interventional

The aim of the study is to test whether the distal radius bone marrow show significant difference in the fat fraction in young women compared to post menopausal women with and without osteoporosis.

NCT ID: NCT03563235 Not yet recruiting - Clinical trials for Postmenopausal Osteoporoses

Clinical Study on Treatment of Postmenopausal Osteoporosis (Kidney Deficiency and Blood Stasis Syndrome) With Xulin Jiangu Granules

Start date: September 1, 2019
Phase: Early Phase 1
Study type: Interventional

Osteoporosis is a common senile disease with a high incidence. The Chinese medicine differentiation treatment has small side effects and can be taken for a long time, which has certain advantages. This project adopts the experience of the person in charge of the project-Xulin Jiangu Granules and clinically collects patients with postmenopausal osteoporosis (kidney deficiency and blood stasis syndrome).

NCT ID: NCT03518268 Not yet recruiting - Breast Cancer Clinical Trials

Vivomixx for Prevention of Bone Loss in Women With Breast Cancer Treated With an Aromatase Inhibitor

Start date: January 2019
Phase: Phase 1/Phase 2
Study type: Interventional

This study evaluates the efficacy of the probiotic food supplement Vivomixx in the prevention of bone loss occurring in post menopausal women with breast cancer treated with an aromatase inhibitor. Half of the participants will receive Vivomixx while the other half will receive a placebo. The primary endpoint is to assess changes of bone turnover markers during the period of 6 months.

NCT ID: NCT03448276 Not yet recruiting - Osteoporosis Clinical Trials

Immediate Effect Of Whole-Body Vibration And Walk in Osteoporosis/Osteopenia

Start date: February 26, 2018
Phase: N/A
Study type: Interventional

Introduction: Osteoporosis and Osteopenia are common bone disorders, characterized by low bone mass, signs of bone deterioration and are responsible for typical bone fragility. Physical activity is certainly a valid prevention tool because it contributes to a healthy energy balance, increasing muscle mass and providing beneficial effects in bone metabolism. Stress induced by more vigorous activities such as weight lifting, increases the risk of injury, particularly in the elderly. Therefore, alternative strategies with lower risk of injury are indicated such as whole body vibration and walk. Objective: Compare the effect whole body vibration and walking on muscular strength, balance and functional performance in the elderly with Osteoporosis and Osteopenia Methods: It is a clinical trial study, controlled, parallel, randomized and blind, which will follow the guidelines established in the Consolidated Standards of Reporting Trials (CONSORT). Participants will be randomly distributed in 2 groups: the experimental group (GI) that will hold the training in the vibrating platform and the control group (GC) that will perform the walk, settling 1 treatment session. All participants will be subjected to the initial and final assessment.

NCT ID: NCT03435094 Not yet recruiting - Clinical trials for Osteoporosis, Postmenopausal

Effect of Alendronate 70mg Formulation on Bone Turnover Markers and Patient Reported Outcomes

Start date: February 25, 2018
Phase: N/A
Study type: Observational

Compare the data obtained with two formulations of alendronate 70 mg (tablets vs effervescent tablet for buffered solution) on the change in bone turnover markers, on gastric tolerance and on treatment adherence (including compliance and persistence).

NCT ID: NCT03399227 Not yet recruiting - Osteoporosis Clinical Trials

Liver Transplantation: Skeletal Effects

Start date: May 1, 2019
Study type: Observational

Fifty patients awaiting liver transplantation and 50 age and gender matched control subjects with normal liver function will be included in the study. The aim of this project is to compare liver transplantation recipients'bone microarchitecture with healthy controls and to evaluate patients' changes within one year after transplantation