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HIV Infections clinical trials

View clinical trials related to HIV Infections.

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NCT ID: NCT00130286 Completed - HIV Infections Clinical Trials

Growth Hormone and/or Rosiglitazone for HIV-Associated Increased Abdominal Fat and Insulin Resistance

Start date: March 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is to determine if the combination of recombinant human growth hormone plus rosiglitazone (an insulin-sensitizing drug) is safe and more effective than either drug alone (or no active therapy) for the treatment of fat accumulation in people with HIV infection and insulin resistance.

NCT ID: NCT00130273 Completed - HIV Infections Clinical Trials

Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV

MAPS
Start date: July 2005
Phase: N/A
Study type: Interventional

This study will determine whether a managed problem solving intervention can help patients with HIV better follow their anti-HIV drug regimen and can control HIV better than the standard of care.

NCT ID: NCT00130078 Recruiting - HIV Infections Clinical Trials

Trial of SAVVY Vaginal Gel and HIV in Nigeria

Start date: September 2004
Phase: Phase 3
Study type: Interventional

Heterosexual contact is now the primary route of transmission for HIV worldwide. This study is a phase 3 trial designed to determine the effectiveness and safety of the 1.0% C31G (SAVVY) vaginal gel for the prevention of male-to-female transmission of HIV among women at high risk.

NCT ID: NCT00129532 Active, not recruiting - HIV Infections Clinical Trials

Trial of SAVVY and HIV in Ghana

Start date: January 2004
Phase: Phase 3
Study type: Interventional

Heterosexual contact is now the primary route of transmission for HIV worldwide. This study is a phase 3 trial designed to determine the effectiveness and safety of the 1.0% C31G (SAVVY) vaginal gel for the prevention of male-to-female transmission of HIV among women at high risk.

NCT ID: NCT00129194 Completed - HIV Infections Clinical Trials

Study of KP-1461 for the Treatment of HIV Positive Patients Who Have Failed Multiple HAART Regimens

Start date: August 2005
Phase: Phase 1
Study type: Interventional

The primary purpose of the study is to assess the safety and pharmacokinetics of KP-1461 given every 12 hours for 14 days when administered to HIV+ patients who have failed multiple highly active antiretroviral therapy (HAART) regimens. Patients currently on HAART will be required to discontinue all HAART medications for up to 6 weeks after screening eligibility has been determined.

NCT ID: NCT00128908 Terminated - HIV Infections Clinical Trials

Sequential HIV Therapy in Treatment Resistant HIV-1 Infected Patients

Start date: September 2005
Phase: Phase 4
Study type: Interventional

This is an open label, crossover pilot study to explore the safety and efficacy of a rapid cycling regimen of antiretroviral combination therapy in HIV-1 infected patients with virus harboring genotypic resistance to at least three classes of antiretroviral therapy.

NCT ID: NCT00128830 Completed - Clinical trials for Human Immunodeficiency Virus Type 1

A Study With TMC125 in Human Immunodeficiency Virus (HIV) Type 1 Infected Patients, Who Were Treated With TMC125 Arm in a Sponsor-Selected TMC125 Study

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the long-term safety and tolerability of etravirine, administered as part of an individually optimized antiretroviral therapy (ART), in human immunodeficiency virus Type 1 (HIV-1) infected participants.

NCT ID: NCT00128063 Completed - HIV Infections Clinical Trials

Succinylated Human Serum Albumin (Suc-HSA) for HIV-1 Infection

Start date: August 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The primary objective of the study is to evaluate the pharmacokinetic behavior of Suc-HSA after consecutive daily intravenous (i.v.) doses. The secondary objectives are to evaluate the safety and tolerability and the antiretroviral and immunological effects of consecutive daily i.v. doses of Suc-HSA.

NCT ID: NCT00127972 Completed - HIV Infections Clinical Trials

2NN & CHARM Long-Term Follow-up Study

Start date: February 2004
Phase: Phase 4
Study type: Interventional

It is desirable to obtain extended follow up data on subjects who participated in the 2NN study and the CHARM study in order to see if the beneficial effect of using nevirapine continues up to 144 weeks of treatment.

NCT ID: NCT00127959 Completed - HIV Infections Clinical Trials

Virological and Clinical Anti-Hepatitis B Virus (HBV) Efficacy of Tenofovir and Emtricitabine in Patients With HIV/HBV co-Infection

Start date: March 2004
Phase: Phase 4
Study type: Interventional

This is a randomized multicentre trial of emtricitabine (FTC) versus tenofovir (TDF)/FTC in antiretroviral naive subjects with HIV/HBV co-infection over 48 weeks (Clinical Trial A). Plus, a 12 week viral kinetic substudy comparing a subgroup of patients on Clinical Trial A is being conducted. (Substudy A1)