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HIV Infections clinical trials

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NCT ID: NCT00002447 Completed - HIV Infections Clinical Trials

A Study to Compare Two Anti-HIV Drug Combinations

Start date: October 1999
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare 2 anti-HIV drug combinations.

NCT ID: NCT00002446 Completed - HIV Infections Clinical Trials

Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients

Start date: August 1998
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of 2 treatments for thrush (a fungal infection of the mouth and throat) in HIV-positive patients. Fluconazole is a drug that is commonly used to treat thrush. SCH 56592 is a new drug that will be compared to fluconazole.

NCT ID: NCT00002445 Completed - HIV Infections Clinical Trials

Safety and Effectiveness of an Experimental Drug, IM862, in Treating Kaposi's Sarcoma in AIDS Patients

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if it is safe and effective to use IM862 to treat Kaposi's sarcoma (KS) in AIDS patients.

NCT ID: NCT00002444 Completed - HIV Infections Clinical Trials

A Study of Nitazoxanide in the Treatment of AIDS-Related Diarrhea

Start date: October 1995
Phase: Phase 1
Study type: Interventional

To determine the pharmacokinetics profile of single doses of nitazoxanide (NTZ) in patients with AIDS-related cryptosporidial diarrhea. To determine steady state concentrations of NTZ following repeated dosing. To assess the safety and efficacy of 4 dose levels of NTZ in these patients. Cryptosporidial enterocolitis in AIDS patients is frequently chronic and severe, contributing substantially to morbidity, mortality, and health care costs in this population. NTZ exhibits antimicrobial activity that may extend to Cryptosporidial infection.

NCT ID: NCT00002443 Completed - HIV Infections Clinical Trials

The Safety and Effectiveness of MK-639 and Zidovudine, Used Alone and Together, in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

Start date: n/a
Phase: N/A
Study type: Interventional

To compare the effects on CD4 counts and safety of MK-639 (indinavir, IDV) and AZT administered concomitantly to MK-639 alone and AZT alone in HIV-1 seropositive patients.

NCT ID: NCT00002442 Completed - HIV Infections Clinical Trials

A Study to Compare the Safety and Effectiveness of Two Dosing Schedules of Lamivudine in Combination With Two Other Anti-HIV Drugs

Start date: June 1999
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of 2 dosing schedules (once daily vs twice daily) of lamivudine (3TC) given with stavudine (d4T) and either indinavir (IDV) or nelfinavir (NFV) for 24 weeks.

NCT ID: NCT00002441 Completed - HIV Infections Clinical Trials

Effectiveness of an HIV Vaccine in HIV-Negative Adults in North America Who Are at Risk of HIV Infection

Start date: n/a
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if an HIV vaccine, AIDSVAX B/B, can protect adults who are at risk from becoming infected with HIV. Patients who become infected despite immunization will be studied to see if receiving the vaccine before becoming infected will help keep HIV levels (viral load) low.

NCT ID: NCT00002440 Completed - HIV Infections Clinical Trials

A Study of 1592U89 in Combination With Protease Inhibitors in HIV-Infected Patients Who Have Never Taken Anti-HIV Drugs

Start date: n/a
Phase: Phase 2
Study type: Interventional

The purpose of this study is to see if it is safe and effective to give 1592U89 plus certain protease inhibitors (PIs) to HIV-infected patients who never have been treated with anti-HIV drugs. This study also examines how the body processes these drugs when they are given together.

NCT ID: NCT00002439 Completed - HIV Infections Clinical Trials

A Study of ALRT 1057 Topical Gel in Patients With AIDS-Related Kaposi's Sarcoma

Start date: n/a
Phase: N/A
Study type: Interventional

The purpose of this study is to see if ALRT1057 gel is safe and effective in treating Kaposi's sarcoma (KS) when applied to skin .

NCT ID: NCT00002438 Completed - HIV Infections Clinical Trials

A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected Patients

Start date: n/a
Phase: N/A
Study type: Interventional

To assess the safety and efficacy of itraconazole versus placebo for prevention of histoplasmosis in HIV-infected patients with CD4 counts < 150 cells/mm3 who reside where histoplasmosis is endemic. To assess the safety and efficacy of itraconazole for preventing other debilitating fungal infections, such as cryptococcosis, aspergillosis, recalcitrant oropharyngeal or vaginal candidiasis, and recurrent esophageal candidiasis.