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NCT ID: NCT05117203 Completed - Healthy Clinical Trials

Dynamic Electrostimulation on the Abdominal Muscles in Healthy Individuals

Start date: November 11, 2021
Phase: N/A
Study type: Interventional

To determine the immediate effects on the abdominal musculature, assessed by ultrasound (RUSI), due to the application of electrostimulation using whole body electrostimulation together with physical exercise in healthy people and to compare with the application of local EMS in the abdominal area and the same physical exercise session. The same intervention is carried out for the control group as the WB-EMS group but simulated.

NCT ID: NCT05113914 Completed - Healthy Clinical Trials

The Age-related Changes of Energy Metabolism in Physically Fit Adult Males

Start date: January 1, 2011
Phase: N/A
Study type: Interventional

The influence of age and physical fitness level on the level of energy metabolism and antioxidant capacity in adult males.

NCT ID: NCT05113719 Completed - Healthy Clinical Trials

Effect of Bridge Exercise Performed at Different Knee Angles

Start date: July 1, 2020
Phase: N/A
Study type: Interventional

Stabilization exercises help increase strength, stability, balance, gait, and endurance through effective abdominal training. Bridge exercise, which is one of the closed kinetic exercises, is one of the most used spinal stabilization exercises. Although that exercise affects on the trunk muscles, it has been stated that it is related to all muscles of the lower extremity.There are some studies, which are examining the activation of the gluteus maximus, quadriceps, rectus abdominus, iliocostalis lumborum, iliocostalis thoracis, and gastrocnemius muscles while exercising the bridge. Although there are some studies investigating the activation of muscles at different knee angles, there is no study in the literature examining the effect of bridge exercise performed at different knee angles on the strength and endurance of lower extremity and trunk muscles. For these reasons, this study aimed to examine the effect of bridging exercises performed at different knee angles on muscle strength and endurance in healthy subjects.

NCT ID: NCT05113511 Completed - Healthy Clinical Trials

PK and Safety of SCT510

Start date: May 9, 2018
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, parallel-controlled phase I clinical study comparing the pharmacokinetics, safety and immunogenicity of SCT510 with bevacizumab (Avastin®) in Chinese healthy males.

NCT ID: NCT05112952 Completed - Healthy Clinical Trials

A Study to Evaluate the Effect of Hepatic Impairment on Lazertinib (JNJ-73841937)

Start date: November 30, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics (PK) of a single oral dose of lazertinib in participants with impaired hepatic function when compared with healthy participants with normal hepatic function, under fed conditions.

NCT ID: NCT05111223 Completed - Healthy Clinical Trials

Testing the Contribution of Orbitofrontal Cortex Networks to Decision-making

Start date: June 16, 2021
Phase: N/A
Study type: Interventional

This research study examines the contribution of orbitofrontal cortex (OFC) networks to decision-making.

NCT ID: NCT05110794 Completed - Healthy Clinical Trials

A Multiple-Dose Study of LY3502970 in Healthy Participants

Start date: November 5, 2021
Phase: Phase 1
Study type: Interventional

The main purpose of this study is to conduct blood tests to measure how much LY3502970 is in the bloodstream and how the body handles and eliminates LY3502970 in healthy participants in fed and fasted states. The study will also evaluate the safety and tolerability of LY3502970 in these participants. The study will last up to 49 days excluding the screening period.

NCT ID: NCT05110027 Completed - Healthy Clinical Trials

Enpatoran Human Mass Balance and Absolute Bioavailability Study

Start date: November 5, 2021
Phase: Phase 1
Study type: Interventional

The purpose of Period 1 of this study is to provide a definitive quantitative characterization of the mass balance, and rates and routes of excretion of enpatoran, and to determine and quantify enpatoran and its metabolites in excreta (urine and feces) and plasma. The purpose of Period 2 of this study is to determine the absolute oral bioavailability of enpatoran. Total minimum duration of study participation for each participant is approximately 50 days.

NCT ID: NCT05109390 Completed - Healthy Clinical Trials

A Study of the Drug Interactions Between Danicopan and Cyclosporine, Tacrolimus, Antacids, and Omeprazole in Healthy Adults

Start date: July 27, 2018
Phase: Phase 1
Study type: Interventional

This was a 3-part study with each part being an open-label, fixed-sequence, 2-period study in healthy adult participants.

NCT ID: NCT05108571 Completed - Healthy Clinical Trials

Phamacokinetics and Safety Profiles of DA-5210 10/1000mg in Healthy Subjects at Fasting State

Start date: October 28, 2021
Phase: Phase 1
Study type: Interventional

Phamacokinetics and safety profiles of DA-5210 10/1000mg in Healthy subjects at Fasting State