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NCT ID: NCT05211752 Completed - Healthy Clinical Trials

Eye Movements Recording Using a Mobile : Comparison to Standard Video-oculography in Young Athletes

e-VOG(YA)
Start date: January 18, 2022
Phase:
Study type: Observational

This study aims to compare measurements obtained through the e-VOG application (mobile application, usable on smartphones or tablets, to measure eye movements) with measurements from the standard video-oculography device (Eye-Tracker®T2), in young athletes.

NCT ID: NCT05209360 Completed - Healthy Clinical Trials

Heel Wedges and Carbon Fiber Custom Dynamic Orthoses to Control Knee Biomechanics

CDOKNEEpilot
Start date: May 9, 2022
Phase: N/A
Study type: Interventional

The proposed study evaluates the effect of medial and lateral wedges and carbon fiber custom dynamic orthoses (CDOs) on lower limb forces and motion during walking. Previous work has used foam wedges of different stiffness and height placed under the heel to alter CDO alignment and alter lower limb mechanics. Medial or lateral wedges have been used by individuals with unilateral knee osteoarthritis in effort to reduce knee loading. In this study, medial and lateral wedges will be placed in participants shoes, with the tall side of the wedge placed on the medial or lateral aspect of the shoes, and participants will walk at controlled and self-selected speeds and complete physical performance measures. Participants will also walk without a CDO. The proposed study will provide evidence that can be used by physicians when treating knee osteoarthritis.

NCT ID: NCT05207839 Completed - Healthy Clinical Trials

Impact of Galacto-Oligosaccharides on Adult Microbiome

Start date: October 27, 2021
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the bifidogenic effect and other potentially beneficial effects on the microbiome of GOS.

NCT ID: NCT05206864 Completed - Healthy Clinical Trials

Food Trial to Evaluate the Safety and Tolerability of SBD111 in Health Adults

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

The aim of the trial is to determine if the synbiotic (prebiotic and probiotic), provided twice daily (capsule) is safe and tolerable in healthy adults.

NCT ID: NCT05206604 Completed - Healthy Clinical Trials

A First-in-human Study of Multiple Doses of Topically Administered PF-07295324 and PF-07259955

Start date: February 9, 2022
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety, (local and systemic) tolerability, and pharmacokinetics following multiple doses of topically applied, maximum feasible formulations of PF-07295324 (0.12% w/w) or PF-07259955 (2% w/w), on approximately 20% body surface area (BSA), in healthy adult participants.

NCT ID: NCT05203822 Completed - Healthy Clinical Trials

Tepotinib Drug-Drug Interaction Study With Itraconazole in Healthy Participants

Start date: January 21, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study was to assess the effect of multiple doses of itraconazole on single dose tepotinib pharmacokinetics in healthy participants. Study details include: Study Duration: up to 48 days Treatment Duration: single dose of tepotinib on Days 1 and 12, 11 days of treatment with itraconazole (Days 8 to 18) Visit Frequency: residence in the Clinical Research Unit from Days -1 to 4 and Days 11 to 15, ambulatory daily visits from Days 5 to 10 and 16 to 20

NCT ID: NCT05203289 Completed - Healthy Clinical Trials

A Study in Healthy People to Test How 2 Different Formulations of BI 695501 Are Taken up by the Body When Given as an Injection

Start date: February 18, 2022
Phase: Phase 1
Study type: Interventional

The main objective of this trial is to compare the pharmacokinetics (PK) of 40 mg BI 695501 100 mg/mL with 40 mg BI 695501 50 mg/mL following single subcutaneous administration.

NCT ID: NCT05202834 Completed - Healthy Clinical Trials

Evaluation of the UltraClear Laser Workstation for Skin Treatment - Histology Study of Laser Ablation on Human Skin

Start date: July 15, 2021
Phase:
Study type: Observational

Evaluation of the UltraClear Laser Workstation for Skin Treatment - Histology Study of Laser Ablation on human skin

NCT ID: NCT05202145 Completed - Healthy Clinical Trials

Drug-Drug Interaction (DDI) Study of ALXN2050 in Healthy Adult Participants

Start date: January 11, 2022
Phase: Phase 1
Study type: Interventional

This study will evaluate the potential drug interactions between ALXN2050 and cyclosporine (Part 1), between ALXN2050 and tacrolimus (Part 2), and between ALXN2050 and mycophenolate mofetil (MMF) (Part 3).

NCT ID: NCT05201937 Completed - Healthy Clinical Trials

A Study of JNJ-64281802 in Healthy Adult Participants

Start date: February 23, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the pharmacokinetics (PK) of JNJ-64281802 in healthy participants when administered in different multiple dose regimens and as different dose strengths.