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Healthy clinical trials

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NCT ID: NCT04675853 Completed - Healthy Clinical Trials

Rapid dEvice Testing pROtocol for Parkinson's Disease

RETRO-PD
Start date: November 25, 2020
Phase:
Study type: Observational

This is an 8 week observational study to evaluate the feasibility of using remote monitoring technologies in future studies of PD. The study will 2 clinical evaluations (one initial, one final), and an 8-week monitoring period including 4 virtual visits where participants will use a combination of digital devices (Emerald touchless sensor system with associated ankle accelerometer, iPhone, Apple Watch, iPad, Fitbit Aria, FitBit Versa, Withings Blood Pressure Monitor Connect, and/or Withings Sleep Mat) during their daily lives.

NCT ID: NCT04674826 Completed - Healthy Clinical Trials

A Trial to Compare the Pharmacokinetics of Tralokinumab in Healthy Subjects

Start date: February 8, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this trial is to compare the pharmacokinetics (PK), safety, tolerability and immunogenicity of a single dose of 300 mg tralokinumab administered as a 1 × X mL subcutaneous (SC) injection with Device A and 2 × Y mL consecutive SC injections with Device B.

NCT ID: NCT04672954 Completed - Healthy Clinical Trials

A Study in Healthy Men to Test How Different Doses of BI 474121 Are Taken up and How They Influence the Amount of a Molecular Messenger (cGMP) in the Spinal Fluid

Start date: January 7, 2021
Phase: Phase 1
Study type: Interventional

The main objectives of this trial are: - To evaluate the effect of BI 474121 on cyclic guanosine monophosphate (cGMP) levels in cerebrospinal fluid (CSF) - To assess the exposure of BI 474121 in CSF relative to plasma - To determine the exposure effect relationship in CSF with different oral doses of BI 474121

NCT ID: NCT04672512 Completed - Healthy Clinical Trials

Single and Multiple Ascending Dose Study of CORT125329 in Healthy Participants

Start date: October 23, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the dose-related safety, tolerability, pharmacokinetics (PK) and pharmacological effects (PD) of CORT125329 after single and multiple ascending oral doses of CORT125329 lipid capsule formulations in healthy participants.

NCT ID: NCT04672499 Completed - Healthy Clinical Trials

Single and Multiple Dose Study of Miricorilant (CORT118335) Tablet Formulations in Healthy Participants

Start date: April 27, 2020
Phase: Phase 1
Study type: Interventional

This study will assess the safety, tolerability, and pharmacokinetics (PK) of miricorilant (CORT118335) tablet formulations following single and multiple oral administration in healthy participants.

NCT ID: NCT04672109 Completed - Healthy Clinical Trials

The Effects of Different Montages of tDCS on Muscle Strength in Healthy Adults

Start date: November 16, 2020
Phase: N/A
Study type: Interventional

To investigate the effects of different montages of tDCS on muscle strength in healthy adults

NCT ID: NCT04671316 Completed - Healthy Clinical Trials

Bioequivalence Study Between "DA-5209 Tab" and "Lixiana Tab"

Start date: November 23, 2020
Phase: Phase 1
Study type: Interventional

An Open-Label, Randomized, 6-sequence, 3-period, Fasting Condition, Single-dose, Per Oral, Cross-over Study to Evaluate the Bioequivalence between "DA-5209 60mg Tab" and "Lixiana 60mg Tab" in Healthy Volunteers

NCT ID: NCT04671069 Completed - Healthy Clinical Trials

Drug Interaction Study of MGL-3196 With Clopidogrel

Start date: July 26, 2019
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether the single and multiple-dose pharmacokinetics (PK) of MGL-3196 are affected by co-administration with clopidogrel in healthy subjects.

NCT ID: NCT04671056 Completed - Healthy Clinical Trials

Drug Interaction Study of MGL-3196 With Pioglitazone

Start date: November 9, 2018
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether the single-dose pharmacokinetics (AUC) of pioglitazone are affected by chronic dosing with MGL-3196 100 mg/day in healthy subjects.

NCT ID: NCT04670796 Completed - Healthy Clinical Trials

A Safety and Pharmacokinetic Study Between HLX02 and Herceptin®(US-licensed and EU-approved) in Healthy Chinese Male Subjects

Start date: March 2, 2021
Phase: Phase 1
Study type: Interventional

Randomised, double-blind, parallel group Phase I study to compare PK profiles and to assess the safety and immunogenicity between HLX02 and Herceptin® (U.S. and EU).