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Healthy clinical trials

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NCT ID: NCT04709094 Completed - Healthy Clinical Trials

A Drug Interaction Study of Danicopan

Start date: July 28, 2019
Phase: Phase 1
Study type: Interventional

This was a 3-part study (Part 1, Part 2, Part 3) with each part being an open-label, fixed sequence, 2-period study in healthy adult participants.

NCT ID: NCT04709081 Completed - Healthy Clinical Trials

A Drug Interaction Study of ACH-0145228

Start date: December 22, 2019
Phase: Phase 1
Study type: Interventional

This was a 2-part study (Part 1 and Part 2), with each part being an open-label, fixed sequence, 2-period study in healthy adult participants.

NCT ID: NCT04708184 Completed - Healthy Clinical Trials

A Study to Assess Relative Bioavailability of and Effect of Food on a New Oral Tablet Formulation of GLPG3970

Start date: January 11, 2021
Phase: Phase 1
Study type: Interventional

This is a study to assess the relative bioavailability of a GLPG3970 oral tablet formulation compared to an oral solution formulation and the effect of food on the bioavailability of a single dose of the oral tablet formulation of GLPG3970. It will also evaluate the safety and tolerability of a single dose of GLPG3970.

NCT ID: NCT04705922 Completed - Healthy Clinical Trials

Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers

Start date: December 29, 2020
Phase: Phase 1
Study type: Interventional

This study is an open-label, 3-way crossover randomized study in adult healthy volunteers to evaluate the relative bioavailability of TT-00420 tablet and capsule formulations and to evaluate food effect on the pharmacokinetics of TT-00420 tablet.

NCT ID: NCT04705610 Completed - Healthy Clinical Trials

Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography

EYE-SEP
Start date: May 23, 2017
Phase: N/A
Study type: Interventional

This study aims to: - analyze prospectively the prevalence of subclinical oculomotor disorders (OMDs) in different phenotypes of Multiple Sclerosis (MS) and to study correlations with brain MRI T2 data. - highlight link between modification of visual exploration strategies to decode emotions, and social behavioral disorders, in patients with demyelinating disease, from early to clinically definite stages.

NCT ID: NCT04705415 Completed - Healthy Clinical Trials

A Single and Multiple Ascending Dose Study of Niclosamide in Healthy Volunteers

Start date: November 17, 2020
Phase: Phase 1
Study type: Interventional

A single and multiple ascending dose study of ANA001 in healthy adults to assess the safety and pharmacokinetics

NCT ID: NCT04705077 Completed - Healthy Clinical Trials

A Study to Assess the Pharmacokinetics and Food Effect of SR419 in Healthy Subjects

Start date: February 2, 2021
Phase: Phase 1
Study type: Interventional

This will be an open-label, single-site, Phase I study to evaluate the PK, safety, and tolerability of SR419 in healthy volunteers.

NCT ID: NCT04704739 Completed - Healthy Clinical Trials

Evaluation of Mass Balance and Absolute Bioavailability of GLPG1205

Start date: January 13, 2021
Phase: Phase 1
Study type: Interventional

A study in healthy male volunteers to assess how the radiolabelled test medicine is taken up and broken down by the body when given by short infusion into a vein and when given by the mouth in the form of a capsule or tablet.

NCT ID: NCT04703348 Completed - Healthy Clinical Trials

The Complex Regional Pain Syndrome (CRPS) is a Chronic Pain Condition. This is a Preliminary Study to Explore and Test Clinical Hypothesis. They Suppose That CRPS Patients Have Impairment in Their Mental or Motor Imagery Abilities.

ImagNimes
Start date: January 12, 2021
Phase: N/A
Study type: Interventional

Medical functional imagery seems to demonstrate that patients suffering from complex regional pain syndrome (CRPS) have cortical modifications that alter their motor (or mental) imagery capacities. Nowadays, the use of motor imagery exercises are used in conventional rehabilitation treatments. But, in clinical practice, no study has verified if patients with CRPS desmonstrate problems in their motor imagery capacities. The MIQ-RS (Motor Imagery Questionnaire - Revised Second) is a valid, reliable and translated into French questionnaire to measure patients' capacities to do mental imagery. In this study, we compare 3 groups of 50 patients : healthy patients, patients with CRPS and patients with musculoskeletal disorder without CRPS. Every patient will take the MIQ-RS for the right and left body side. We hypothesis that patients with CRPS have more deficit than the 2 others to realise motor imagery.

NCT ID: NCT04703023 Completed - Healthy Clinical Trials

Comparison of Water Sorption Capacity and the Composition of Bronchial Fluids of Healthy Persons and Patients With Chronic Obstructive Bronchitis (COPD)

Start date: July 9, 2020
Phase:
Study type: Observational

Pilot basic research study on the properties of bronchial mucus. Examination of the sorption and desorption properties, mucin concentration, and structure of the mucus from healthy airways compared to patients with Chronic Obstructive Pulmonary Disease (COPD).