There are about 173942 clinical studies being (or have been) conducted in United States. The country of the clinical trial is determined by the location of where the clinical research is being studied. Most studies are often held in multiple locations & countries.
Patients will receive 3 cycles of NK cell infusions over 12 weeks. Each cycle will consist of 1 infusion per week for 3 weeks, followed by a rest week (week 4). Dose will be escalated in an inter-patient stepwise fashion consisting of 4 dose levels.
The researchers are investigating if changing an individual's behaviors may have an impact on outcomes for patients with pulmonary arterial hypertension (PAH). This research will test the efficacy of a home-based exercise program to improve exercise tolerance and physical activity.
Background: The National Heart, Lung, and Blood Institute (NHLBI) conducts clinical trials that look at new ways to prevent, detect, or treat disease. It wants to create an NHLBI Recruitment Registry that lets people sign up to be contacted for NHLBI studies. It also wants to make sure that the data people share about themselves is safely stored. Researchers will be able to use this registry to prescreen people for clinical trials. Objective: To create and maintain an NHLBI research participant recruitment registry. This is an observational registry for collecting, storing, and providing access to data on people with a disease or condition of interest, or as a healthy volunteer to the NHLBI. Eligibility: People who contact the NIH to participate in an NHLBI IRB-approved study Design: Researchers will contact participants by telephone to obtain informed consent verbally. Participants will give the following data: - name - date of birth - phone number - address - email address - diagnosis (if applicable) - referring provider. Participants will share how they heard of the study. They may give their medical records. They may be asked if they were enrolled in an NHLBI study in the past. Participants will be asked if they would like to be contacted for other current or future studies. If they say no, they will not be contacted. But their data will stay in the database. They can also withdraw from the registry. If they do, their reason will be recorded in the database. The registry will be created and maintained by the Office of the Clinical Director at NHLBI.
The purpose of this research is to explore how women evaluate photos of other women posted on social media sites. There are two factors the investigators plan to explore in an online experiment: (a) the degree to which body positive images appear to be sexualized or not; and (b) whether or not there is evidence of photo modification on these images. The results of this work will provide greater understanding into the effects of the body positive movement and determine conditions under which these campaigns are most impactful.
This is a 12-week study of oral tolfenamic acid vs. placebo in Progressive Supranuclear Palsy (PSP)
8-week pilot study looking at the impact of Joovv's infrared photo modulation product on male and female hormone levels.
The primary goal of this tissue collection protocol is to establish a framework for the acquisition and banking of biospecimen collected from men undergoing brachytherapy. Biopsies of the prostate is an invasive procedure; however, in this tissue collection protocol, biopsies are acquired intraoperatively while patients are prepped for brachytherapy seed placement, thus minimizing the inconvenience of the biopsy procedure for patients. The utility of these biopsies will provide a valuable resource for molecular assessments.
Investigating the effects of interrupting various lengths of prolonged sitting with bike sprints on post prandial lipemia the next day. We will conduct three trials, one control, one with two-hour sitting intervals (total of 4 bouts of bike sprints) and one with 6-hour sitting intervals I total of two bouts of bike sprints). A milkshake high fat tolerance test will be conducted the next day and whole body fat oxidation as well as triglyceride area under the curve will be measured every hour for the duration of the 6-hour test.
Single Center, Double Blind, Placebo- Controlled Study of 20 subjects with 10 active drug/10 placebo Standardized baseline/pre-treatments and follow-up images will be taken. Subjects will receive injection of either study drug or placebo to the Depressor Anguli Oris. Follow ups will occur at 2 weeks, 4 weeks, and 12 weeks.
The investigators propose utilizing a simple telemedical protocol to allow patients to substitute the first post-operative visit with a remote survey that includes essential post-operative history, vision measurement, and photographs, all of which can be provided using a personal computer, tablet, or smart phone. The investigators have selected for this purpose a subset of oculoplastic procedures involving the eyelid and lacrimal system that have well-reported low rates of serious complications, since high-risk procedures will likely always require close, in-person care. The investigators hypothesize that telemedicine follow-up for the first post-operative week after low-risk oculoplastic surgery will decrease the time burden on patients without compromising their satisfaction or increase the risk of late post-operative complications.