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Clinical Trial Summary

Patients will receive 3 cycles of NK cell infusions over 12 weeks. Each cycle will consist of 1 infusion per week for 3 weeks, followed by a rest week (week 4). Dose will be escalated in an inter-patient stepwise fashion consisting of 4 dose levels.


Clinical Trial Description

Patient enrollment will follow a 3+3 design. Patients will receive 3 cycles of NK cell infusions over 12 weeks. Each cycle will consist of 1 infusion per week for 3 weeks, followed by a rest week (week 4). Dose will be escalated in an inter-patient stepwise fashion consisting of 4 dose levels until dose limiting toxicities are observed or the recommended phase II dose is determined. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04254419
Study type Interventional
Source Nationwide Children's Hospital
Contact Melinda Triplet, RN
Phone 614-722-6039
Email Melinda.Triplet@nationwidechildrens.org
Status Not yet recruiting
Phase Phase 1
Start date December 2023
Completion date October 2025

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