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NCT ID: NCT01652690 Completed - Clinical trials for Osteoporosis, Postmenopausal

Prospective Observational Study to Describe Characteristics and Management of Patients Treated With Denosumab (Prolia®) in Routine Clinical Practice

Start date: June 26, 2012
Phase:
Study type: Observational

The objective of this prospective, observational study in Czech Republic and Slovakia is to describe per country the characteristics of women treated with denosumab in routine clinical practice and the clinical management of these patients during the first 2 years of treatment. In addition, the study aims to collect safety data in the real-life clinical practice settings on adverse drug reactions (ADRs) and serious ADRs.

NCT ID: NCT01649557 Completed - Schizophrenia Clinical Trials

Multicenter, Open-label, Safety and Tolerability Study

STEP 210
Start date: August 2009
Phase: Phase 2
Study type: Interventional

This will be a multicenter, 52 week, open label study to assess the safety and tolerability of oral OPC-34712 (1 to 6 mg) as monotherapy in adult patients with schizophrenia. The study will be conducted on an outpatient basis. Enrollment into the study will be drawn from eligible subjects who have completed participation in Study 331-07- 203 and who, in the investigator's judgment, would benefit from continued treatment with oral OPC-34712.

NCT ID: NCT01647516 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety Study of Ozanimod in Ulcerative Colitis

Touchstone
Start date: December 26, 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether RPC1063 is effective in the treatment of ulcerative colitis (UC).

NCT ID: NCT01640951 Completed - Clinical trials for Moderate to Severe Chronic Plaque-Type Psoriasis

4 Year Extension Study of Efficacy and Safety of Secukinumab in Patients With Moderate to Severe Chronic Plaque-type Psoriasis

Start date: September 16, 2012
Phase: Phase 3
Study type: Interventional

CAIN457A2304E1 was an extension study to two phase III studies, CAIN457A2304 and CAIN457A2307 (core studies). This extension study planned to collect up to four years of long-term safety, tolerability and efficacy data of secukinumab in both the fixed interval regimen and the retreatment at start of relapse regimen. All subjects who completed the full study treatment period (52 weeks) in the cores studies CAIN457A2304 and CAIN457A2307 were eligible to participate in this extension study. In this extension study, the prefilled syringe (PFS) liquid formulation of secukinumab was used.

NCT ID: NCT01638000 Completed - Urologic Diseases Clinical Trials

A Study to Evaluate the Efficacy and Safety of Mirabegron Compared to Solifenacin in Patients With Overactive Bladder Who Were Previously Treated With Another Medicine But Were Not Satisfied With That Treatment.

BEYOND
Start date: June 12, 2012
Phase: Phase 3
Study type: Interventional

The purpose of the study was to assess the efficacy, safety and tolerability of mirabegron 50 mg versus (vs) solifenacin 5 mg in the treatment of patients with OAB who were dissatisfied with their treatment due to lack of efficacy.

NCT ID: NCT01634152 Completed - Asthma Clinical Trials

Efficacy and Safety of 2 Doses of Tiotropium Respimat® Compared to Placebo in Children With Severe Persistent Asthma

Start date: July 2012
Phase: Phase 3
Study type: Interventional

The overall purpose of the trial is to evaluate efficacy and safety of tiotropium inhalation solution (2.5 mcg and 5 mcg) delivered via Respimat® inhaler once daily in the evening over 12 weeks, compared to placebo, as add-on controller therapy on top of usual care in children (6 to 11 years old) with severe persistent asthma.

NCT ID: NCT01631214 Completed - Clinical trials for Postmenopausal Women With Osteoporosis

Study to Determine the Efficacy and Safety of Romosozumab in the Treatment of Postmenopausal Women With Osteoporosis

ARCH
Start date: May 4, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if treatment is effective in preventing fractures in women with postmenopausal osteoporosis.

NCT ID: NCT01624259 Completed - Type 2 Diabetes Clinical Trials

A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes

AWARD-6
Start date: June 2012
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the benefits and risks of once-weekly dulaglutide compared to once-daily liraglutide in participants with type 2 diabetes who have inadequate glycemic control on metformin.

NCT ID: NCT01620762 Completed - Rhinoconjunctivitis Clinical Trials

Phase III Cat-PAD Study

Start date: October 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the treatment effect of two treatment regimens of Cat-PAD vs placebo and to evaluates the treatment effect of Cat-PAD on symptoms, rescue medication usage and Quality of Life.

NCT ID: NCT01620255 Completed - Ulcerative Colitis Clinical Trials

A Study Of PF-00547659 In Patients With Moderate To Severe Ulcerative Colitis

TURANDOT
Start date: November 2, 2012
Phase: Phase 2
Study type: Interventional

To determine the dose or doses of PF-00547659 that will be the most effective to improve or halt the disease symptoms in patients with moderate to severe ulcerative colitis.