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NCT ID: NCT00922714 Terminated - ICU Patients Clinical Trials

Scandinavian Intensive Care Unit (ICU) Glutamine Study

Start date: October 2003
Phase: Phase 4
Study type: Interventional

This is a prospective double-blinded placebo-controlled block randomized study in intensive care patients comparing intravenous glutamine supplementation to placebo. The hypothesis is an improvement of clinical outcome. The primary endpoint is a reduction in the Sequential Organ Failure Assessment (SOFA) score on day 7 of treatment.

NCT ID: NCT00921492 Completed - Clinical trials for Polycystic Ovary Syndrome

Acupuncture and Gonadotropin-releasing Hormone Pulse Generator and Stress Axis in Polycystic Ovary Syndrome

PCOSLFEA
Start date: February 2009
Phase: N/A
Study type: Interventional

Hypothesis The overall hypothesis is that non-obese (BMI <30) women with PCOS have high luteinising hormone (LH) and cortisol pulse frequency and amplitude and that repeated low-frequency EA restore these alterations and induce ovulation.

NCT ID: NCT00920946 Completed - Huntington Disease Clinical Trials

A Safety and Efficacy Study of Dimebon in Patients With Huntington Disease

HORIZON
Start date: July 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if Dimebon is safe and effective for the treatment of cognitive impairment in Huntington disease.

NCT ID: NCT00918515 Completed - Healthy Clinical Trials

Study to Assess the Safety, Tolerability and Pharmacokinetics and Pharmacodynamics of AZD3043

Start date: May 2009
Phase: Phase 1
Study type: Interventional

This is a Phase I, single centre, open label study to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics of intravenous AZD3043 after single ascending doses in healthy male volunteers.

NCT ID: NCT00918398 Completed - Healthy Clinical Trials

AZD1981 Bioavailability Study of Intravenous (IV) and Oral Formulations

Start date: June 2009
Phase: Phase 1
Study type: Interventional

The primary objective is to investigate the pharmacokinetics of AZD1981 given in different formulations and to measure renal clearance

NCT ID: NCT00917995 Completed - Parastomal Hernia Clinical Trials

Trial Concerning the Frequency of Parastomal Hernia With or Without a Mesh

STOMAMESH
Start date: January 2008
Phase: Phase 2/Phase 3
Study type: Interventional

Specific aim: To compare patients with colostomies with or without mesh at the primary operation. Primary endpoint is the incidence of parastomal hernia requiring surgery. All patients at participating centers scheduled for permanent colostomy, after signing informed consent and meeting inclusion criteria, will be randomised to formation of a stoma with or without mesh. If the inclusion criteria is fulfilled and informed consent is signed, the patient is randomised preoperatively.

NCT ID: NCT00917514 Completed - Ulcerative Colitis Clinical Trials

An Investigational Study to Test Usability of the Electronic Dosing Equipment Medicpen

Start date: June 2009
Phase: N/A
Study type: Observational

This is a study of the electronical dosing tool MedicPen and it's qualities with regards to user friendliness and medication compliance.

NCT ID: NCT00916409 Completed - Clinical trials for Glioblastoma Multiforme

Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The study is a prospective, randomly controlled pivotal trial, designed to test the efficacy and safety of a medical device, the NovoTTF-100A, as an adjuvant to the best standard of care in the treatment of newly diagnosed GBM patients. The device is an experimental, portable, battery operated device for chronic administration of alternating electric fields (termed TTFields or TTF) to the region of the malignant tumor, by means of surface, insulated electrode arrays.

NCT ID: NCT00916318 Recruiting - Childhood Obesity Clinical Trials

Childhood Overweight

Start date: August 2008
Phase: N/A
Study type: Interventional

To evaluate the effects of a family-based intervention program intended for parents of pre-school children (4-6 y) with overweight and obesity (according to Cole et al), and to investigate if treatment has an effect on metabolic parameters. In a randomised controlled trial evaluate the three separate family based intervention programs and to investigate if treatment has an effect by correlating the parameters described above with BMI, before and after the intervention program.

NCT ID: NCT00915772 Completed - Clinical trials for Diabetes Mellitus, Type 2

Treatment of Type 2 Diabetes With Linagliptin 2.5 mg Bid + Metformin 500 or 1000 mg Bid and Metformin 1000 mg Bid

Start date: June 2009
Phase: Phase 3
Study type: Interventional

A phase III randomised, double-blind parallel group extension study to investigate the efficacy and safety of twice daily administration of the free combination of linagliptin 2.5 mg + metformin 500 mg or of linagliptin 2.5 mg + metformin 1000 mg versus monotherapy with metformin 1000 mg twice daily over 54 weeks in type 2 diabetic patients previously completing the double-blind part of study 1218.46