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NCT ID: NCT03948815 Recruiting - Child Birth Clinical Trials

Room 4 Birth - An Adaptable Birthing Room and the Effect on Labour and Birth

R4B
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Healthcare Environment influences health outcomes. The effects of physical aspects of the birthing room on maternal and neonatal outcomes is insufficiently studied. This study will measure and compare effects and experiences of two types of birthing rooms.

NCT ID: NCT03947840 Recruiting - Physical Activity Clinical Trials

Physical Activity and Its Impact on Colon Cancer Surgery

PACOS
Start date: January 30, 2019
Phase:
Study type: Observational [Patient Registry]

This is a prospective clinical study that studies how the physical activity level before operation of colon cancer affects the outcome of complication and histology. The hypothesis is that people who are more physical active have less postoperative complications and different histology around the tumor. We are testing the patients before the surgery with physical tests for fitness, strength and physical activity level. Questionnaires are also filled by the patients for pain, anxiety, depression and motivation for life style changes. Their body mass is analyzed with a DEXA (Dual-energy X-ray absorptiometry scan). For one years we are monitoring their activity and follow up for physical tests, DEXA and questionnaires is at 6 and 12 months. The histology is analyzed after surgery to se if we have a different inflammatory response around the tumor.

NCT ID: NCT03946098 Not yet recruiting - Gambling Disorder Clinical Trials

iCBT for GD: Protocol for an Open Feasibility Trial

iCBTGD
Start date: August 1, 2019
Phase: N/A
Study type: Interventional

Gambling Disorder (GD) is a major public health concern worldwide. As awareness of GD has risen, treatment demand is increasing, and internet interventions is a promising alternative for providing fast, evidence-based treatment at scale, to a low cost. This article presents the protocol of an open label, uncontrolled pilot and feasibility trial of a novel internet-delivered cognitive behavioral treatment, conducted in regular addiction care with adult treatment-seeking patients (max N=25) with problematic gambling, with or without psychiatric comorbidity. Weekly measures of gambling symptoms and gambling will serve as outcome measures. Study results will further guide the development of the intervention and its implementation into regular addiction care.

NCT ID: NCT03945708 Recruiting - Clinical trials for Infective Endocarditis

Does Whole Blood Adsorber During CPB Reduce the Amount of Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery?

Start date: May 2019
Phase: Phase 4
Study type: Interventional

The study aims to investigate the effect of addition of an adsorber during cardio pulmonary bypassin patients with infective endocarditis undergoing valve surgery, and if it will decrease the use of vasoactive drugs postoperatively.

NCT ID: NCT03944772 Not yet recruiting - Clinical trials for Non-Small Cell Lung Cancer

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

ORCHARD
Start date: May 14, 2019
Phase: Phase 2
Study type: Interventional

Phase 2 Platform Study in Patients with Advanced Non-Small Lung Cancer who progressed on First-Line Osimertinib Therapy. This study is modular in design, allowing evaluation of the efficacy, safety and tolerability of multiple study treatments.

NCT ID: NCT03943147 Recruiting - Lupus Nephritis Clinical Trials

An Investigational Study to Evaluate the Safety and Effectiveness of BMS-986165 With Background Treatment in Participants With Lupus Nephritis

Start date: April 19, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of BMS-986165 compared with placebo with regard to measures of kidney function in participants with lupus nephritis (LN).

NCT ID: NCT03942146 Completed - Smoking Cessation Clinical Trials

Smoking Cessation Prior to Gynecological Surgery

Start date: November 5, 2015
Phase: N/A
Study type: Interventional

This study evaluates whether current smokers scheduled for gynecological surgery will stop smoking to a higher extent if they or the surgeon is exposed to information on smoking cessation prior to surgery in a web-based questionnaire in the Swedish National quality register for gynecological surgery, GynOp.

NCT ID: NCT03940443 Not yet recruiting - Clinical trials for Traumatic Brain Injury

Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS

Start date: May 15, 2019
Phase:
Study type: Observational

Introduction: Patients suffering a time-critical medical condition require rapid prehospital assessment and treatment and most often quick transportation to definitive care. This can be decisive for patient outcome. In order to minimize time from assessment to treatment, thus lowering mortality and morbidity, it is important to have a well-coordinated chain of care. The efficient use of Ground Emergency Medical Services (GEMS) and Helicopter Emergency Medical Services (HEMS) is essential in such a chain of care. Objectives: The aim is to describe differences in mortality, morbidity, assessment and treatment of two time-critical conditions, traumatic brain injury (TBI) and acute myocardial infarction (MI), in patients assessed by GEMS and HEMS respectively. Method: The project consists of a descriptive observational study and comparative cohort study. Inclusion criteria are patients considered to be suffering from TBI and acute MI, which are treated by GEMS or HEMS in the regions of Uppsala, Jämtland/Härjedalen, Dalarna and Värmland. Clinical significance: The results expect to be the basis for further studies aiming to optimize the utilization of GEMS and HEMS.

NCT ID: NCT03939767 Not yet recruiting - Clinical trials for Wet Age-related Macular Degeneration

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease

XTEND
Start date: May 15, 2019
Phase:
Study type: Observational

In this observational study researchers want to learn more about changes in visual acuity (clarity of vision) with proactive flexible treatments over time in patients suffering from wet age-related macular degeneration (wAMD) after decision to treat with Aflibercept (Eylea) was made. Wet AMD is an eye disease that progressively destroys the macula, the central portion of the retina, impairing central vision.

NCT ID: NCT03938805 Active, not recruiting - Clinical trials for Cardiovascular Diseases

I-CBT Tailored to Patients With Cardiovascular Disease and Insomnia

Hit-IT
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

The Hit-IT study is based on an internet-based cognitive behavioral therapy program tailored to patients with different types of cardiovascular diseases and insomnia. A randomized controlled trial design is used. A 9 weeks internet-based cognitive behavioral therapy intervention vs a 3 weeks sleep hygiene education.