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NCT ID: NCT00097084 Completed - Clinical trials for Diabetes Mellitus, Type 2

Comparison of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart in Type 2 Diabetes

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and the United States of America (USA). The purpose of this study is to test whether insulin detemir is a safe and at least as effective alternative to insulin glargine for the control of blood glucose in basal/bolus therapy in patients with type 2 diabetes.

NCT ID: NCT00095238 Completed - Clinical trials for Congestive Heart Failure

Irbesartan in Heart Failure With Preserved Systolic Function (I-Preserve)

Start date: June 2002
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn if Irbesartan is superior to placebo in reducing mortality and cardiovascular morbidity in subjects with heart failure with preserved systolic function. The safety of this treatment will also be studied.

NCT ID: NCT00095147 Completed - Clinical trials for Rheumatoid Arthritis

Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn if Abatacept or Infliximab in combination with Methotrexate demonstrate a greater reduction in disease activity over placebo.

NCT ID: NCT00095082 Completed - Diabetes Clinical Trials

Safety and Efficacy of Insulin Detemir Plus Insulin Aspart Against Insulin Glargine Plus Insulin Aspart as Mealtime Insulin in Type 1 Diabetes

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe and the United States of America (USA). The purpose of this study is to test whether insulin detemir is a safe and at least as effective alternative to insulin glargine for the control of blood glucose in basal/bolus therapy in patients with type I diabetes.

NCT ID: NCT00094497 Completed - Clinical trials for Carcinoma, Adrenal Cortical

Trial in Locally Advanced and Metastatic Adrenocortical Carcinoma Treatment (FIRM-ACT)

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether treatment with etoposide, doxorubicin, cisplatin and mitotane (EDP/M) prolongs survival as compared to streptozotocin and mitotane (Sz/M) in patients with advanced adrenocortical carcinoma (ACC) whose disease is not amenable to complete surgical resection.

NCT ID: NCT00094458 Completed - Crohn Disease Clinical Trials

Trial Comparing Infliximab and Infliximab and Azathioprine in the Treatment of Patients With Crohn's Disease na�ve to Both Immunomodulators and Biologic Therapy (Study of Biologic and Immunomodulator Naive Patients in Chrohn's Disease: SONIC

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and effectiveness of three different treatments for patients with Crohns disease who have not responded to previous treatment with a group of drugs commonly used to treat Crohn's Disease (5-ASA) and corticosteroids. Patients will receive either infliximab (a drug used to treat autoimmune diseases) or azathioprine (an immunosuppressant or drug used to suppress the immune system) or a combination of both for up to 34 weeks. This research study will involve approximately 500 patients. The main study involves up to 34 weeks (approximately 8 months). A study extension of an additional 20 weeks (approximately 5 months) is optional for patients who successfully complete the main study. A country-specific study extension of open label infliximab treatment for an additional 1 year is optional for patients who successfully complete the main study extension.

NCT ID: NCT00093041 Completed - Clinical trials for Head and Neck Neoplasms

Zalutumumab in Head and Neck Cancer

Start date: December 1, 2003
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this trial is to determine the safety of zalutumumab as a treatment for head and neck cancer.

NCT ID: NCT00091650 Completed - Clinical trials for Borderline Personality Disorder

Olanzapine in Patients With Borderline Personality Disorder

Start date: March 2004
Phase: Phase 3
Study type: Interventional

The goals of this study are to determine: the safety of olanzapine and any side effects that might be associated with it, how olanzapine compares to placebo, whether olanzapine can help patients with symptoms of Borderline Personality Disorder (BPD), and how much olanzapine should be given to patients.

NCT ID: NCT00091637 Completed - Clinical trials for Acute Myocardial Infarction

Pexelizumab in Conjunction With Angioplasty in Acute Myocardial Infarction (APEX-AMI)

Start date: April 2004
Phase: Phase 3
Study type: Interventional

In the setting of reperfusion therapy in an acute myocardial infarction using primary percutaneous intervention (PCI), the body's own inflammatory system involving the complement cascade may be harmful. This study will test the safety and efficacy of a novel complement inhibitor, pexelizumab to reduce mortality at 30 days.

NCT ID: NCT00090753 Completed - Anemia Clinical Trials

A Study of Intravenous or Subcutaneous Methoxy Polyethylene Glycol-Epoetin Beta (RO0503821, Mircera) in Chronic Kidney Disease Patients With Renal Anemia

Start date: October 2004
Phase: Phase 3
Study type: Interventional

This study assessed the long-term efficacy, safety, and tolerability of intravenous (iv) or subcutaneous (sc) methoxy polyethylene glycol-epoetin beta in chronic kidney disease patients with renal anemia. Eligible patients were those who were receiving stable maintenance therapy with methoxy polyethylene glycol-epoetin beta or erythropoiesis stimulating agents (ESAs) in Phase II or III clinical studies. They continued to receive methoxy polyethylene glycol-epoetin beta or comparator ESAs at the same weekly dose and by the same route of administration (sc or iv) as in the qualifying studies.