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NCT ID: NCT00681746 Completed - Anxiety Clinical Trials

Positron Emission Tomography (PET) Study With (11C) Flumazenil to Determine Central GABAA Receptor Occupancy of AZD6280

PET
Start date: February 2008
Phase: Phase 1
Study type: Interventional

The study is carried out in order to determine the relationship between the dose of AZD6280 and the blood concentration of AZD6280, and to investigate to which extent AZD6280 binds to GABAA receptors

NCT ID: NCT00681720 Completed - Anxiety Clinical Trials

Positron Emission Tomography (PET) Study With (11C)Flumazenil to Determine Central GABAA Receptor Occupancy of AZD7325

PET
Start date: February 2008
Phase: Phase 1
Study type: Interventional

The study is carried out in order to determine the relationship between the dose of AZD7325 and the blood concentration of AZD7325, and to investigate to which extent AZD7325 binds to the GABAA receptors.

NCT ID: NCT00681486 Completed - Cancer Clinical Trials

Ghrelin - A Possible Opportunity to Improve Appetite

Phase 3
Start date: October 2003
Phase: Phase 3
Study type: Interventional

The study is designed to evaluate whether ghrelin treatment can improve appetite in weight losing cancer patients.

NCT ID: NCT00681187 Completed - Clinical trials for Neuroendocrine Tumour With Carcinoid Symptoms

Somatuline Autogel Preference and Health Economy Study

SAPHE
Start date: June 2008
Phase: Phase 4
Study type: Interventional

The primary aim of this study is to assess which method of lanreotide Autogel administration patients with neuroendocrine tumours prefer - self/partner administrations or healthcare provided administrations. The study will also assess if self/partner administration can be performed without loss of efficacy and with a preserved safety profile. The impact of self/partner administration on resource utilisation and costs will be studied. In addition, we will also assess the healthcare provider's experience of the two administration practices.

NCT ID: NCT00681122 Completed - Breast Cancer Clinical Trials

CARIATIDE (Compliance of ARomatase Inhibitors AssessmenT In Daily Practice Through Educational Approach)

CARIATIDE
Start date: May 2008
Phase: N/A
Study type: Observational

This observational study is restricted to postmenopausal women with hormone-sensitive early breast cancer, who have decided to take prescribed adjuvant use of AIs, anastrozole or letrozole, according to the current product SmPCs. There is no Investigational Medicinal Product (IMP) to be taken in this observational study. The adjuvant AI medication must not have exceeded thirteen weeks. In CARIATIDE (Compliance of ARomatase Inhibitors AssessmenT In Daily practicE through Educational approach), impact of educational material on women's compliance and persistence rates will be evaluated.

NCT ID: NCT00680992 Completed - Cancer Clinical Trials

Study of Denosumab in Subjects With Giant Cell Tumor of Bone

Start date: September 9, 2008
Phase: Phase 2
Study type: Interventional

To determine how safe denosumab is in treating subjects with giant cell tumor of bone (GCTB)

NCT ID: NCT00680550 Completed - Atrial Fibrillation Clinical Trials

INSIGHT (R)XT. Indications for Diagnosis, Arrhythmia and Monitoring of Reveal XT

Start date: April 2008
Phase: N/A
Study type: Observational

To describe the clinical indications for Reveal XT in diagnosis and continuous monitoring of arrhythmia and to explore the clinical applications and outcome of arrhythmia monitoring on patient care.

NCT ID: NCT00680186 Completed - Thromboembolism Clinical Trials

Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE)

RE-COVER II
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The general aim of this study is to determine the comparative safety and efficacy of dabigatran etexilate 150 mg bid administered orally and warfarin Pro re nata (As needed/PRN) to maintain an International Normalised Ratio (INR) of 2.0-3.0 for 6 month treatment of acute symptomatic VTE. The primary objective is to investigate the efficacy of dabigatran compared to warfarin during the 6 month treatment period. The investigation of other selected efficacy aspects and safety are regarded as secondary objective of this trial.

NCT ID: NCT00679731 Completed - Psoriasis Clinical Trials

A Study of Safety and Efficacy Comparing ABT-874 Versus Methotrexate in Subjects With Moderate to Severe Plaque Psoriasis

Start date: April 2008
Phase: Phase 3
Study type: Interventional

This study is being conducted to compare the efficacy of ABT-874 versus Methotrexate in subjects with moderate to severe plaque psoriasis.

NCT ID: NCT00679588 Completed - Clinical trials for Venous Thromboembolism

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery

SAVE-ABDO
Start date: April 2008
Phase: Phase 3
Study type: Interventional

The primary objective is to compare the efficacy and safety of once daily (q.d.) subcutaneous (s.c.) injections of Semuloparin sodium (AVE5026) with q.d. s.c. injections of Enoxaparin for the prevention of Venous Thromboembolic Events (VTE) in patients undergoing major abdominal surgery. The secondary objectives are to evaluate the safety of Semuloparin sodium (AVE5026) and to document Semuloparin sodium (AVE5026) exposure in this population.