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NCT ID: NCT00094302 Completed - Clinical trials for Cardiovascular Diseases

Aldosterone Antagonist Therapy for Adults With Heart Failure and Preserved Systolic Function

TOPCAT
Start date: August 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of aldosterone antagonist therapy in reducing cardiovascular mortality, aborted cardiac arrest, and heart failure hospitalization in patients who have heart failure with preserved systolic function.

NCT ID: NCT00093288 Completed - Clinical trials for Depressive Disorder, Major

Major Depressive Disorder In The Elderly

Start date: June 2004
Phase: Phase 3
Study type: Interventional

This is a placebo-controlled study evaluating the effectiveness of medication in elderly subjects with Major Depressive Disorder (MDD).

NCT ID: NCT00093093 Completed - Chronic Hepatitis C Clinical Trials

Study of Viramidine to Ribavirin in Patients With Chronic Hepatitis C Who Are Treatment Naive

VISER2
Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the safety and effectiveness of viramidine to ribavirin in chronic hepatitis C patients who have never before received treatment.

NCT ID: NCT00091442 Completed - Breast Cancer Clinical Trials

A Study of Docetaxel Monotherapy or DOXIL and Docetaxel in Patients With Advanced Breast Cancer

Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate whether the time to progression for the DOXIL and docetaxel combination therapy group was superior to that of the group treated with docetaxel monotherapy in participants with advanced breast cancer.

NCT ID: NCT00090753 Completed - Anemia Clinical Trials

A Study of Intravenous or Subcutaneous Methoxy Polyethylene Glycol-Epoetin Beta (RO0503821, Mircera) in Chronic Kidney Disease Patients With Renal Anemia

Start date: October 2004
Phase: Phase 3
Study type: Interventional

This study assessed the long-term efficacy, safety, and tolerability of intravenous (iv) or subcutaneous (sc) methoxy polyethylene glycol-epoetin beta in chronic kidney disease patients with renal anemia. Eligible patients were those who were receiving stable maintenance therapy with methoxy polyethylene glycol-epoetin beta or erythropoiesis stimulating agents (ESAs) in Phase II or III clinical studies. They continued to receive methoxy polyethylene glycol-epoetin beta or comparator ESAs at the same weekly dose and by the same route of administration (sc or iv) as in the qualifying studies.

NCT ID: NCT00090519 Completed - Clinical trials for Diabetic Retinopathy

Reduction in the Occurrence of Center-Involved Diabetic Macular Edema

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if ruboxistaurin can help slow the worsening of an eye disease called macular edema in patients with diabetes.

NCT ID: NCT00090324 Completed - Schizophrenia Clinical Trials

Quetiapine Fumarate (SEROQUEL) Compared to Placebo in the Treatment of Adolescent Patients With Schizophrenia

ANCHOR 112
Start date: September 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to demonstrate efficacy and safety of quetiapine fumarate (SEROQUEL) compared with placebo in the treatment of adolescent patients with schizophrenia.

NCT ID: NCT00090051 Completed - Clinical trials for Chronic Lymphocytic Leukemia

FCR Versus FC Alone in the Treatment of Chronic Lymphocytic Leukemia (CLL) in Relapsed Patients

Start date: July 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to provide treatment for patients who have chronic lymphocytic leukemia (CLL), and to compare the use of rituximab added to fludarabine+cyclophosphamide (FC) with FC alone, to determine if rituximab lengthens the time a patient remains free of leukemia symptoms.

NCT ID: NCT00090038 Completed - Clinical trials for Non-Hodgkin's Lymphoma

Effect of Rituximab on Immunological Recall Response to Specific Antigens in the Treatment of Non-Hodgkin's Lymphoma

Start date: October 2003
Phase: Phase 4
Study type: Interventional

The purpose of this study is to provide treatment for patients who have relapsed Non-Hodgkin's lymphoma (NHL) or refractory NHL, and to test the immunity of study subjects after receiving four treatments with rituximab.

NCT ID: NCT00089986 Completed - Sepsis Clinical Trials

GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults

Start date: September 2004
Phase: Phase 2
Study type: Interventional

The primary objective is to estimate the size of the GR270773 treatment effect on 28-day all-cause mortality for two doses of GR270773 versus placebo in adult subjects with suspected or confirmed Gram-negative severe sepsis. GR270773 will be administered as a three-day continuous intravenous infusion.