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NCT ID: NCT00275197 Completed - Clinical trials for Depressive Disorder, Major

A Research Study to Compare the Treatments of a Combination of Elzasonan With Zoloft, to Zoloft Alone, or Placebo in People With Major Depressive Disorder (MDD)

Start date: December 2005
Phase: Phase 2
Study type: Interventional

The major purpose of the study is to help determine whether giving the combination of Elzasonan with Zoloft to people with depression is a better treatment than taking Zoloft alone. This study will also compare the safety and tolerability of Elzasonan and Zoloft combination to Zoloft alone or placebo.

NCT ID: NCT00274443 Completed - Clinical trials for Non-Small Cell Lung Cancer (NSCLC)

An Open Label Study in Patients With Advanced NSCLC With ABI-007(Abraxane) in Combination With Carboplatin

Start date: March 1, 2005
Phase: Phase 2
Study type: Interventional

This is an open-label dose escalation trial using ABI-007 plus carboplatin.

NCT ID: NCT00273546 Completed - Cancer Clinical Trials

Induction Chemotherapy Comparing Taxotere® Cisplatin and 5-Fluorouracil (TPF) With Standard Cisplatin and 5-Fluorouracil (PF) Followed by Chemoradiation in Locally Advanced Head and Neck Cancer

Start date: May 1999
Phase: Phase 3
Study type: Interventional

- 1.To compare overall survival after treatment with the test tri-therapy (TPF: docetaxel plus cisplatin and 5FU) or the control treatment (PF: cisplatin plus 5-FU) followed by chemoradiotherapy in patients with locally advanced SCCHN. - 2.The main secondary endpoint is progression free survival (PFS). The other secondary endpoints are to evaluate and compare improvement of local symptoms; time-to-treatment failure; quality of life; clinical complete response rate (CR and CR/PR); toxicity and to evaluate the relationship of tumor markers and response to therapy.

NCT ID: NCT00269516 Completed - Clinical trials for Early Stage Parkinson's Disease

SLV308 for Treatment of Patients With Early Parkinson's Disease

Start date: June 2006
Phase: Phase 3
Study type: Interventional

This study is a multicenter, randomized, double blind, parallel group study of 6 months' treatment with SLV308 administered as a monotherapy in patients with early stage PD. An open label safety extension to this study is planned as a separate protocol for patients who are willing and eligible to participate.

NCT ID: NCT00268892 Completed - Prostate Cancer Clinical Trials

Extension Study Investigating the Long-Term Safety of Degarelix Three-Month Depots in Patients With Prostate Cancer

Start date: January 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this extension study was to collect long-term safety and tolerability information to support a marketing authorisation application for a three-month dosage regimen of degarelix.

NCT ID: NCT00268697 Completed - Clinical trials for Hypercholesterolemia

Efficacy of Lapaquistat Acetate Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.

Start date: October 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine the efficacy of lapaquistat acetate, once daily (QD), taken with ezetimibe on cholesterol levels in subjects with primary dyslipidemia

NCT ID: NCT00268216 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

Survival Of Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Start date: September 2000
Phase: Phase 3
Study type: Interventional

The purpose of this study is to see if fluticasone 500mcg/salmeterol 50mcg can improve the survival of subjects with COPD and also assess the long term safety profile of this drug.

NCT ID: NCT00266747 Completed - Anxiety Disorders Clinical Trials

An Eight-Week Study to Evaluate the Efficacy and Safety of SR58611A in Patients With Generalized Anxiety Disorder

AQUARIUS
Start date: December 2005
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of SR58611A in patients with Generalized Anxiety Disorder. The primary objective is to evaluate the efficacy of a 700 mg dose of SR58611A compared to placebo in patients with generalized anxiety disorder (GAD).The secondary objectives are to evaluate the efficacy of SR58611A on disability and quality of life in patients with GAD and to evaluate safety of SR58611A.

NCT ID: NCT00264914 Completed - Hyponatremia Clinical Trials

Safety and Efficacy of SR121463B in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion

SIADH Safety
Start date: July 2005
Phase: Phase 3
Study type: Interventional

To determine the long-term safety and tolerability of SR121463B in patients with syndrome of inappropriate antidiuretic secretion (SIADH). To assess the long-term efficacy of SR121463B in maintaining normal levels of serum sodium in patients with SIADH. Long term safety is evaluated further in an open label extension study with flexible doses of satavaptan.

NCT ID: NCT00264667 Completed - Clinical trials for Metabolic Syndrome X

Study In Patients With Dyslipidaemia

Start date: December 2005
Phase: Phase 2
Study type: Interventional

Study in patients with dyslipidaemia.