Clinical Trials Logo

Pulmonary Disease, Chronic Obstructive clinical trials

View clinical trials related to Pulmonary Disease, Chronic Obstructive.

Filter by:

NCT ID: NCT03584269 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Innovation in NOn Invasive Ventilation in COPD Patients Treated by Long Term Oxygen Therapy

INOV-LTOT
Start date: June 28, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the efficacy of non-invasive ventilation (NIV) on nocturnal hypoventilation in patients with chronic obstructive pulmonary disease (COPD) who are on long term oxygen therapy (LTOT) at home.

NCT ID: NCT03583099 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

CAPTURE
Start date: July 15, 2018
Phase: N/A
Study type: Interventional

A prospective, multicenter study including a cross-section validation to define sensitivity and specificity of CAPTURE to identify previously undiagnosed patients with clinically significant Chronic Obstructive Pulmonary Disease (COPD), and its impact on clinical care across a broad range of primary care settings in a cluster randomized controlled clinical trial.

NCT ID: NCT03581227 Not yet recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1)

CAPTURE
Start date: July 15, 2018
Phase:
Study type: Observational

A prospective multi-center study to define the sensitivity and specificity of CAPTURE for identifying previously undiagnosed patients with clinically significant COPD in a broad range of primary care settings.

NCT ID: NCT03577795 Not yet recruiting - Clinical trials for Pulmonary Disease, Chronic Obstructive

A Prospective Cohort Study of Asthma and COPD Overlap in Japanese COPD Patients Using the Diagnostic Criteria of The Japanese Respiratory Society

ACO-Registry
Start date: June 30, 2018
Phase:
Study type: Observational [Patient Registry]

This study is a multicentered and non-interventional prospective cohort study. Study centers shall be the institutions where the examinations, adopted in the ACO diagnostic criteria9) from The Japanese Respiratory Society, are performed at least once a year as a part of their regular practice. Physicians participating in the study will consecutively register by means of central registration outpatients who have the characteristics of COPD in the ACO diagnostic criteria9) from The Japanese Respiratory Society, and who have been confirmed to satisfy the inclusion criteria whereas not violating the exclusion criteria.

NCT ID: NCT03577080 Completed - COPD Clinical Trials

Chronic Obstructive Pulmonary Disease

COPD
Start date: October 28, 2016
Phase: N/A
Study type: Interventional

Chronic Obstructive Pulmonary Disease (COPD) is a preventable respiratory characterized by airflow obstruction that is not fully reversible. This disease a major cause of mortality worldwide. It is projected to rank the third-leading cause of death in 2020. The objective of this study is to examine the effects of a physical therapy intervention in stable patients with COPD.

NCT ID: NCT03577002 Not yet recruiting - Cancer Clinical Trials

Team-based Versus Primary Care Clinician-led Advance Care Planning in Practice-based Research Networks

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

This project compares two models of the Serious Illness Care Program (SICP) in primary care: clinician-focused SICP and team-based SICP. Discussion and planning for serious illness care can help patients identify what is most important to them and assure they receive care that best matches their goals and values, such as spending more time at home or not being in pain.

NCT ID: NCT03573817 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Subjects With COPD

Start date: May 31, 2018
Phase: Phase 3
Study type: Interventional

A Phase 3b, 42-day, Randomized, Double-Blind, Placebo‚ąíControlled, Parallel Group Study to Evaluate the Safety and Tolerability of Nebulized Revefenacin and Nebulized Formoterol Fumarate (PERFOROMIST®) Administered in Sequence and as a Combined Solution in Subjects with Chronic Obstructive Pulmonary Disease

NCT ID: NCT03570359 Active, not recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

A Study to Test a Potential New Treatment for COPD Patients Suffering From the Common Cold or Influenza

Start date: January 29, 2018
Phase: Phase 2
Study type: Interventional

The aim of the study is to assess the safety of inhaled SNG001 and the ability of inhaled SNG001 to 'switch on' the cells' anti-viral defences in patients with chronic obstructive pulmonary disease (COPD). The study consist of two parts. Part 1 will assess the safety of inhaled SNG001 in ten patients with stable COPD. Part 2 will assess efficacy and safety of inhaled SNG001 in 80 patients with COPD with a cold or COPD exacerbation.

NCT ID: NCT03569384 Recruiting - COPD Clinical Trials

Feasibility & Effect of a Tele-rehabilitation Program for Chronic Obstructive Pulmonary Disease vs. Standard Rehabilitation

TELEKOL-1
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Introduction In order to guarantee chronic patients and elderly a high quality service from health care organizations in the coming decades, new technologies have been implemented to treat patients from a distance. There is still a need for more studies on the efficacy and cost-effectiveness of tele-rehabilitation (TR) and its long-term effects needs also to be determined. To guarantee individuals with chronic obstructive pulmonary diseases (COPD) a high quality service from health care organizations in the coming decades and economically save the national health systems for an expensive bill for the treatment of COPD, new actions plans has to be taken into use. Hereby, more patients can be treated with less human resources while still sustaining or even improving today's services. The importance of such welfare action plans has to maintain a high quality of service that individuals with COPD are willing to accept. Here, TR seems to be a good welfare action plans. Despite proof of improved cost-effectiveness, no studies support the benefits of TR in COPD patient with respect to adherence, security, treatment efficacy and improved quality of life. Aim To assess and compare the feasibility and effect of a tele-rehabilitation program with a new and innovative TR platform (NITRP) compared to standard treatment with respect to exercise capacity, quality of life and activities of daily living in patients with COPD. Method and material The study is a prospective randomized controlled trial comparing the effects of tele-rehabilitation and conventional rehabilitation in patients with severe COPD. 54 patients fulfilling the inclusion criteria will be randomized in two groups to either a 8 week tele-rehabilitation program or a conventional COPD rehabilitation program at the hospital. Participants will be tested at baseline, 8 weeks, 3 and 6 months after cessation of the training programs. In the intervention group, a real- and a virtual physiotherapist agent will facilitate the rehabilitation. Ethical considerations This study will not pose any risk to the patient as compared to current practice. Participation is voluntary and the patient may at any time withdraw from the study without consequences for future care or treatment. The questionnaires and the test methods used are clinically recognized instruments. Signed informed consent will be obtained from the all participants after verbal and written information and before the study starts. The study will not be initiated before approval from the Ethics Committee and the Data Protection Agency has been obtained. The study will follow the general research ethical rules as expressed in the Helsinki Declaration II.

NCT ID: NCT03568747 Recruiting - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy and Mechanism of NIV in Relieving Dyspnea After Exercise in Patients With Stable Severe COPD

Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Exertional dyspnea is a major cause of exercise limitation and anxiety, and contributes importantly to reduced quality of life for patients with COPD. The aim of this study is to determine the efficacy and mechanism of NIV with a dual-limb circuit plus oxygen therapy in relieving exertional dyspnea in patients with severe COPD, so as to provide a guidance for clinical use for NIV.