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NCT ID: NCT00660179 Completed - Clinical trials for Pulmonary Arterial Hypertension

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

SERAPHIN
Start date: May 2008
Phase: Phase 3
Study type: Interventional

The AC-055-302/SERAPHIN study will be an event-driven Phase III study, comparing two different doses of macitentan (ACT-064992) (3 and 10 mg) vs placebo in patients with symptomatic PAH. The main study objective is to demonstrate that macitentan (ACT-064992) prolongs time to the first morbidity or mortality event, and to evaluate the benefit/risk profile of macitentan (ACT-064992) in the treatment of patients with symptomatic PAH.

NCT ID: NCT00659412 Completed - Psoriatic Arthritis Clinical Trials

A Placebo-controlled Study With an Extension Examining the Safety and Efficacy of Alefacept in Psoriatic Arthritis

Start date: September 2003
Phase: Phase 2
Study type: Interventional

Randomized, double-blind, 24-week study of patients with psoriatic arthritis comparing alefacept + methotrexate (MTX) vs. placebo + MTX followed by a 24-week open-label extension with only alefacept + MTX treatment.

NCT ID: NCT00659295 Completed - Clinical trials for Diabetes Mellitus, Type 2

Observational Study to Evaluate the Safety of Levemir® in Diabetes

PREDICTIVE™
Start date: June 2004
Phase: N/A
Study type: Observational

This study is conducted in Africa, Asia, Europe, Japan and South America. The aim of this observational study is to evaluate the incidence of serious adverse reactions (SARs) while using Levemir® (insulin detemir) under normal clinical practice conditions. Study conducted globally in 26 countries. Some countries participated in the study for only 3 months (Austria, Brazil, Denmark, Germany, Israel, Lebanon, Slovenia, Russia, and Turkey), while others extended their participation to 6 (Belgium/Luxembourg, Czech Republic, Greece, India, Italy, Netherlands, Saudi Arabia, South Africa, South Korea, Sweden, Tunisia, and United Kingdom/Ireland) and 12 months (Finland, France, and Japan), respectively.

NCT ID: NCT00659282 Completed - Clinical trials for Diabetes Mellitus, Type 2

Observational Study of Safety and Effectiveness of NovoMix® 30 for the Treatment of Diabetes

IMPROVE™
Start date: September 11, 2006
Phase: N/A
Study type: Observational

This study is conducted in Asia, Europe, Japan and North America. The aim of this observational study is to evaluate the safety and effectiveness while using NovoMix® 30 during 26 weeks under normal clinical practice, in the countries participating in the study. The primary outcome is the incidence of major hypoglycaemic events reported as serious adverse drugs reaction conditions on hypoglycaemic events.

NCT ID: NCT00658021 Completed - Type 2 Diabetes Clinical Trials

Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes

Start date: May 30, 2008
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to test the hypothesis that glycemic control, as measured by change in hemoglobin A1c (HbA1c) from baseline to endpoint, with exenatide is superior to that of placebo after 28 weeks of treatment in adolescent patients with type 2 diabetes who are naïve to antidiabetes agents, or patients who are being treated with metformin, an SU, or a combination of metformin and an SU

NCT ID: NCT00657644 Completed - Clinical trials for Erectile Dysfunction

Efficacy and Safety of Vardenafil in Men With Erectile Dysfunction

Start date: August 2003
Phase: Phase 3
Study type: Interventional

To find out more information on how effective and safe vardenafil is at treating impotence in men living in Russia.

NCT ID: NCT00656890 Completed - Ulcerative Colitis Clinical Trials

A Study of MDX-1100 in Subjects With Active Ulcerative Colitis

MDX1100-06
Start date: April 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and tolerability of the MDX-1100 regimen in subjects with active Ulcerative colitis(UC) and determine the response rate at day 57 in patients administered MDX-1100.

NCT ID: NCT00656305 Completed - Multiple Myeloma Clinical Trials

ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain

Start date: March 2008
Phase: N/A
Study type: Interventional

A Pivotal Study to Evaluate the Effectiveness and Safety of ExAblate Treatment of Metastatic Bone and Multiple Myeloma Tumors for the Palliation of Pain in Patients Who are not Candidates for Radiation Therapy

NCT ID: NCT00655044 Completed - Clinical trials for Diabetes Mellitus, Type 2

Evaluation of Levemir® for the Treatment of Type 1 and 2 Diabetes

PREDICTIVE™
Start date: May 2007
Phase: N/A
Study type: Observational

This study is conducted in Europe. The aim of this observational study is to evaluate the incidence of serious adverse drug reactions while using Levemir® under normal clinical practice conditions.

NCT ID: NCT00653185 Completed - Diabetes Mellitus Clinical Trials

Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus

Start date: May 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine the efficacy, safety and tolerability of SYR-472, once daily (QD), in subjects with Type 2 Diabetes Mellitus.