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NCT ID: NCT00652925 Completed - Clinical trials for Arthritis, Juvenile Rheumatoid

A Study to Evaluate the Efficacy and Safety of Celecoxib Suspension Compared to Naproxen Suspension in Patients With JRA

Start date: October 2002
Phase: Phase 3
Study type: Interventional

To study Celebrex versus naproxen to see if it decreases symptoms of juvenile arthritis such as pain and swelling.

NCT ID: NCT00652470 Completed - Hydrocephalus Clinical Trials

A Study Comparing Two Treatments for Infants With Hydrocephalus

Start date: September 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to study whether infants with triventricular hydrocephalus (TVH) have a better long-term outcome at 5 years when they are treated with a new procedure, endoscopic third ventriculostomy (ETV), than infants treated with the more traditional treatment, insertion of a cerebrospinal fluid (CSF) shunt.

NCT ID: NCT00648596 Completed - Clinical trials for Erectile Dysfunction

A Study to Evaluate Self-esteem and Relationships in Males With Erectile Dysfuntion

Start date: May 2003
Phase: Phase 4
Study type: Interventional

To determine the improvement in the self-esteem domain score of the Self-Esteem/Overall Relationship (SEAR) questionnaire and the improvement in erectile function (obtained from the Erectile Function [EF] domain of the International Index of Erectile Function [IIEF]). Furthermore, to determine if the improvement obtained in self-esteem was related to the main erectile dysfunction (ED) co-morbidities type and/or number.

NCT ID: NCT00646542 Completed - Clinical trials for Diabetes Mellitus, Type 2

Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency

Start date: March 2005
Phase: Phase 3
Study type: Interventional

This clinical trial is designed to provide additional information on the safety and tolerability of vildagliptin (50 mg once daily (qd)) when used in patients with type 2 diabetes mellitus (T2DM) and moderate or severe renal insufficiency.

NCT ID: NCT00644449 Completed - Bronchitis, Chronic Clinical Trials

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis

Start date: January 2003
Phase: Phase 3
Study type: Interventional

This study was performed to confirm that a single 2.0-g dose of azithromycin SR is at least as effective as 7 days of levofloxacin 500 mg/day in adults with acute exacerbation of chronic bronchitis Secondary objectives: To assess safety and the bacteriologic efficacy of both treatment regimens

NCT ID: NCT00643929 Completed - Clinical trials for Purpura, Thrombocytopaenic, Idiopathic

LENS - Long-term Eltrombopag Observational Study

LENS
Start date: February 2007
Phase: N/A
Study type: Observational

A long term observational ocular safety study in adults who have received study medication (either active drug or placebo) in a phase II or III clinical study evaluating eltrombopag. The study will follow subjects for 2.5 years following their last ocular assessment on their prior treatment study (regardless of the therapeutic indication) and will describe long-term ocular safety with respect to changes in the lenses over time from all subjects.

NCT ID: NCT00643851 Completed - Type 2 Diabetes Clinical Trials

An Efficacy & Safety Study of BMS-512148 in Combination With Metformin Extended Release Tablets

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The purpose of this clinical research study is to learn if initiating treatment with BMS-51248 (Dapagliflozin) in combination with metformin XR can improve diabetes control in patients with Type 2 Diabetes who do not receive any pharmacological treatment for diabetes, when compared to initial treatment with monotherapy dapagliflozin or metformin XR. The safety of this treatment will also be studied

NCT ID: NCT00643734 Completed - Pneumonia Clinical Trials

A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Mild to Moderate Pneumonia in Adult Patients

Start date: April 2003
Phase: Phase 3
Study type: Interventional

The study was performed to see if a single, 2.0-g oral dose of azithromycin sustained release (SR) was at least as effective as a 7-day regimen of levofloxacin (500 mg once daily) for the treatment of mild to moderate community-acquired pneumonia, and to assess the efficacy and safety of both treatment regimens.

NCT ID: NCT00643565 Completed - Sarcoma Clinical Trials

A Study of Avastin (Bevacizumab) in Combination With Standard Chemotherapy in Children and Adolescents With Sarcoma.

Start date: July 29, 2008
Phase: Phase 2
Study type: Interventional

This open-label two-arm study will assess the safety and efficacy of a combination of bevacizumab + standard chemotherapy with standard chemotherapy alone as active comparator in childhood and adolescent patients with metastatic rhabdomyosarcoma or non-rhabdomyosarcoma soft tissue sarcoma. Patients will be randomized to receive bevacizumab + standard chemotherapy or standard chemotherapy alone. Treatment will consist of 9 x 3-week cycles of induction treatment (standard chemotherapy with or without bevacizumab 7.5 mg/kg iv on day 1 of each cycle) followed by 12 x 4-week cycles of maintenance treatment (standard chemotherapy with or without bevacizumab 5 mg/kg iv on days 1 and 15 of each cycle). The anticipated time on study treatment is 1-2 years.

NCT ID: NCT00643513 Completed - Breast Cancer Clinical Trials

Quality Of Life While Receiving Faslodex

Start date: June 2007
Phase: N/A
Study type: Observational

To study QoL related response, symptom spectrum and severity in disseminated breast cancer patients receiving Faslodex hormonal therapy.