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NCT ID: NCT00862147 Terminated - Child Development Clinical Trials

Effectiveness Study of the International Child Development Program

Start date: January 2007
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the effect of the International Child Development Program (ICDP). Research questions to be answered: 1. Does the ICDP affect children's psychosocial functioning compared to treatment as usual? 2. Does the ICDP change parent-child interaction?

NCT ID: NCT00856661 Terminated - Stroke Clinical Trials

Efficacy and Safety Study of Desmoteplase to Treat Acute Ischemic Stroke (DIAS-4)

Start date: April 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine whether desmoteplase is effective and safe in the treatment of patients with acute ischaemic stroke when given within 3 to 9 hours from onset of stroke symptoms.

NCT ID: NCT00844727 Terminated - Duodenal Polyposis Clinical Trials

Coxib-inhibition of Duodenal Polyp Growth in FAP

Start date: September 2003
Phase: Phase 2/Phase 3
Study type: Interventional

Preliminary data indicate a protective effect on the development of duodenal polyps by coxib treatment. The hypothesis of the present study is that normal therapy doses of rofecoxib for 1 year would stop or reverse the development of premalignant adenomatous lesions in the duodenal mucosa of FAP patients.

NCT ID: NCT00831441 Terminated - Clinical trials for Acute Coronary Syndrome

Phase III Acute Coronary Syndrome

APPRAISE-2
Start date: March 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if apixaban is superior to placebo for preventing cardiovascular death, non-fatal myocardial infarction, or ischemic stroke in subjects with a recent acute coronary syndrome

NCT ID: NCT00796445 Terminated - Melanoma Clinical Trials

A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor

Start date: December 1, 2008
Phase: Phase 3
Study type: Interventional

The purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after surgical removal of their tumor. This Protocol Posting has been updated following Amendments 1 of the Protocol, March 2010. The impacted sections are outcome measures and entry criteria.

NCT ID: NCT00764413 Terminated - Multiple Sclerosis Clinical Trials

Chronotherapy in Acute Multiple Sclerosis (MS) Attack

Start date: April 2009
Phase: N/A
Study type: Interventional

The Immunological system is showing a diurnal rhythmicity. The Mediators that enhances inflammation are at highest level during the night. At the same time the endogenous production of cortisol is at its lowest. We want to study if there is a better effect of treatment with Methylprednisolone for acute MS-attacks if given at nighttime. The effect will be measured in relation to neurological deficits and function with Kurtzkes Expanded Disability Status Score (EDSS) and Multiple Sclerosis Functional Composite (MSFC). We want to see if the mean improvement in EDSS is greater in the group receiving treatment at night opposed to the group that get treatment during the daytime.

NCT ID: NCT00751933 Terminated - Ulcerative Colitis Clinical Trials

Vaccines and Dietary Oats in the Treatment of Ulcerative Colitis

Start date: October 2008
Phase: Phase 2
Study type: Interventional

Ulcerative colitis is a chronic inflammatory bowel disease caused by an imbalance between natural defence mechanisms in the intestinal mucosa and microbes in the intestinal lumen. We hypothesise that an improvement or even normalisation of this balance may be achieved by the use of vaccines and dietary oats. The combined use of oral typhoid vaccine and cholera/ETEC-vaccine is supposed to stimulate mucosal defence factors, while dietary oats modifies the microbial environment inside the intestinal lumen. Or study aim is to show if such treatment brings symptom relief to patients with ulcerative colitis.

NCT ID: NCT00742482 Terminated - Clinical trials for Acute Respiratory Distress Syndrome

Efficacy and Safety of 3 Doses of HL10 Given at Fixed Time Intervals Compared to Standard Therapy

Start date: January 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy and safety of three doses of HL 10 given at fixed time intervals compared to standard therapy

NCT ID: NCT00735722 Terminated - Atrial Fibrillation Clinical Trials

A(f)MAZE-CABG Study

AFMAZE-CABG
Start date: July 2009
Phase: N/A
Study type: Interventional

Concomitant AF ablation with HIFU in patients with persistent or long standing persistent AF undergoing CABG will be superior in restoring SR, compared with patients with persistent or long standing persistent AF undergoing CABG treated with best medical treatment according to ACC/AHA/ESC 2006 guidelines and no AF ablation.

NCT ID: NCT00729027 Terminated - Clinical trials for Hypercholesterolemia

Evaluation of Safety and Efficacy of AVE5530 as add-on to Ongoing Statins in Patients With Primary Hypercholesterolemia

Start date: July 2008
Phase: Phase 3
Study type: Interventional

The present study is assessing the efficacy and safety of AVE5530 (25 mg and 50 mg) in add-on to ongoing statin treatment in a double-blind manner in comparison with placebo, in the management of patients with primary hypercholesterolemia considered as inadequately controlled despite their ongoing statin treatment. The main objective is to evaluate the effects of the association AVE5530+statin on LDL-C level reduction after 12 weeks of treatment. The effects of AVE5530 on other lipid parameters will be assessed as secondary objectives.