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NCT ID: NCT03182972 Recruiting - Clinical trials for Medication Reconciliation Implementation

Implementation Study on Medication Reconciliation Among Pharmacists in Two Tertiary Hospitals in Southwestern Nigeria

Start date: August 2, 2016
Phase: N/A
Study type: Interventional

This study will assess the current practice of medication reconciliation among pharmacists in the selected institutions with a view to making an intervention to address gaps discovered

NCT ID: NCT03173729 Recruiting - Colorectal Cancer Clinical Trials

Point of Care Test to Diagnosed Colorectal Cancer and Polyps in Low Middle Income Countries

Start date: February 11, 2017
Phase: N/A
Study type: Observational

This is a-two phase study. Phase 1 will adapt a 3-metabolite biosensor that identifies patients with colorectal cancer (CRC) and precancerous polyps to Nigerian patients. Phase 2 will pilot test and evaluate the point-of-care (POC) biosensor device in Nigeria.

NCT ID: NCT03152006 Not yet recruiting - HIV/AIDS Clinical Trials

Adolescent Coordinated Transition Nigerian HIV+ Youth

ACT
Start date: June 1, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the comparative effectiveness of a comprehensive, coordinated transition protocol which includes an early introduction to the adult provider, an integrated case management team and a peer-facilitated organized support group on retention in care, viral suppression and psychosocial wellbeing among adolescents living with HIV.

NCT ID: NCT03140904 Not yet recruiting - Clinical trials for Severe Acute Malnutrition

Reducing the Frequency of Follow up and Task Sharing in the Treatment of Uncomplicated Severe Acute Malnutrition

Start date: July 1, 2017
Phase: N/A
Study type: Interventional

This study will be conducted as a stratified cluster randomized trial. The unit of randomization will be the outpatient therapeutic feeding center. The 10 health centers will be stratified by size, and centers within a stratum will be randomized in a 1:1 ratio to one of two schedules of treatment: (1) standard weekly visits or (2) monthly visits with support for home-based surveillance.

NCT ID: NCT03131193 Recruiting - Health Behavior Clinical Trials

Primary Care Provider Supply and Patient Outcomes

Start date: March 20, 2017
Phase: N/A
Study type: Interventional

The evidence on how primary care provider supply and skill relates to patient outcomes is limited and inconclusive. The issue of skill is a particularly important one in low-income countries where the shortage of skilled medical professionals has led to greater use of the task-shifting model in which medical tasks are redistributed from highly skilled health workers to mid-level providers who receive less training. In this large-scale cluster-randomized trial, the investigators randomly select primary health care facilities to receive a highly skilled provider (a doctor), a mid-level health provider, or no additional providers (the control group). The investigators study the effect of this intervention on patient outcomes. Embedded within this trial is another experimental intervention in which pregnant women residing in communities served by the primary health care facilities are assigned to receive a cash transfer conditional on using antenatal, delivery and postnatal care. The investigators study the effect of the cash transfer on health care utilization and on maternal and infant outcomes.

NCT ID: NCT03081949 Recruiting - Clinical trials for Peripartum Cardiomyopathy

Peripartum Cardiomyopathy in Nigeria Registry

PEACE
Start date: June 8, 2017
Phase: Phase 4
Study type: Interventional

Peripartum cardiomyopathy (PPCM) is a global disease with significant morbidity and mortality, and Nigeria probably has the highest burden of the disease in the world. Unfortunately, much about the disease including its aetiology, epidemiology and treatment is not yet well described. This will be a prospective, national, multicenter cohort study, conducted in centres in Nigeria. It is expected that approximately 500 patients with PPCM and 500 apparently healthy pregnant women will be recruited over a 6-month period with follow‐up at 3-monthly intervals for 18 months.

NCT ID: NCT03076996 Recruiting - Health Behavior Clinical Trials

YouthPower Action Feasibility Study of Online Support Group Intervention Among Adolescents Living With HIV in Nigeria

Start date: June 1, 2017
Phase: N/A
Study type: Interventional

This study will examine the feasibility and acceptability of an intervention designed to improve retention in HIV care services and improve anti-retroviral therapy (ART) adherence among adolescents ages 15-19 years living with HIV enrolled in ART services.

NCT ID: NCT03072758 Enrolling by invitation - HIV Infections Clinical Trials

Men's Club: Impact of Male Partner Involvement on Initiation and Sustainment of Exclusive Breastfeeding Among Postpartum Women

Start date: March 30, 2017
Phase: N/A
Study type: Interventional

Breastfeeding remains the optimal mode of feeding for infants younger than six months. Exclusive Breast Feeding (EBF) among HIV-infected mothers has been shown to be associated with a sustained and significant reduction in HIV transmission and has the potential to reduce infant and under-five mortality. Given the considerable authority among men as decision makers in sub-Saharan African, we may be witnessing a missed opportunity to engage men in the education, awareness, and decision-making for EBF. Understanding the role and impact of male partners on this decision-making process require further examination to inform the development of effective and sustainable evidence-based interventions to support the initiation and sustainment of EBF.

NCT ID: NCT03058939 Not yet recruiting - Breast Cancer Clinical Trials

Assessing the Response Rate of Neo-adjuvant Paclitaxel (Taxol) in Nigerian Women With Breast Cancer

Start date: November 2017
Phase: Phase 2
Study type: Interventional

This is a two-stage phase II study with a single arm design. It will be conducted in women with breast cancer with stages IIA to IIIC (defined by AJCC 2009 classification) of all histological subtypes. All patients will receive 16 doses of paclitaxel; three breast ultrasound tests and tumor pathologic response evaluation will be used to assess the response to treatment.

NCT ID: NCT03044899 Completed - Surgery Clinical Trials

African Surgical Outcomes Study (ASOS)

ASOS
Start date: February 1, 2016
Phase: N/A
Study type: Observational [Patient Registry]

STUDY OBJECTIVE To confirm the incidence of in-hospital postoperative complications in adult surgical patients in Africa. STUDY DESIGN Seven day, African national multi-centre prospective observational cohort study of adult (≥18 years) patients undergoing surgery. Patients will be followed up for a maximum of 30 days. We will follow the original International Surgical Outcomes Study (ISOS) study design. The primary outcome is in-hospital postoperative complications in adult surgical patients in Africa. Secondary outcomes include in-hospital mortality and the relationship between postoperative complications and postoperative mortality. The intention is to present a representative sample of surgical outcomes across all African countries. This study will run between February and March 2016.