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NCT ID: NCT03371914 Active, not recruiting - HIV/AIDS Clinical Trials

Costs, Efficiency and the Role of Management in HIV Prevention Interventions for Female Sex Workers in Nigeria

Start date: August 12, 2017
Phase: N/A
Study type: Interventional

This study seeks to measure the costs associated with HIV prevention service delivery to female sex workers (FSW) in Nigeria, as well as examine the relationship between management practices at the community-based organizations (CBOs) and costs. To complete these goals, the study will collect both retrospective and prospective data from CBOs and from centralized information from study partners (Society for Family Health, SFH). In the prospective section of the study, CBOs will be sampled and assigned to either treatment or control groups. Data collected at the CBOs will be aggregated by the CBO managers, and those in the treatment group will receive feedback on their performance on a monthly basis. Those in the treatment group will additionally receive a management training to guide their management practices. Researchers hypothesize that there will be improvements in management indicators and therefore decreases in costs at CBOs in the treatment group. Results will be disseminated to local, national, and international stakeholders.

NCT ID: NCT03348865 Not yet recruiting - Anxiety Disorders Clinical Trials

Fertility Life Counselling Aid- FeLiCiA

FeLiCiA
Start date: November 20, 2017
Phase: N/A
Study type: Interventional

Research Objectives: 1. To test the FeLiCiA, a 6 week intervention developed for the management of psychological morbidities associated with infertility, using external randomised control trial methods, on patients showing positive indicators for psychological morbidity amongst patients with infertility at UCH Ibadan, Nigeria. 2. To explore and understand patient perspectives on the benefits of the FeLiCiA counselling in addition to usual clinical care. Summary of Research: Population: Men & Women (aged 21-45) with GHQ 12 score indicative of mild to moderate psychological morbidities (3 or more). Patients attending University College Hospital for Infertility treatment. Intervention: FELICIA [N=42; 21 intervention; 21 control] 6 weekly counselling Follow up at 6/52 and 6/12. Inclusion Criteria: Age 21-45; Exclusion Criteria: Previously diagnosed mental illness; severe anxiety & depression or suicide intent (immediate referral); Age<21/>45. Comparison: Treatment as usual Outcome: Primary-GHQ score less than 3 Secondary- Patient perspectives on benefits and effectiveness of intervention, and patient empowerment post intervention.

NCT ID: NCT03329482 Completed - Clinical trials for Non Specific Low Back Pain

Pulse Ultrasound and Kneading Massage in Non- Specific Chronic Low Back Pain

NSCLBP
Start date: August 12, 2016
Phase: N/A
Study type: Interventional

Back pain is one of humanity most frequent complains. About nine of ten adults experience back pain at some points in their life and five out of ten working adults have back pain every year. When continued for long period it may constitute a disability which tries the patient of the most stoical individual as well as the doctor called to bring relief to the suffering victim. Kneading massage with topical analgesic is a common practice by physiotherapist especially in Nigeria in the management of low back pain, work has been done to know the efficacy of lofnac gel (topical analgesic) via phonophoresis in the management of low back pain(ojoawo,2015), but the comparison of the efficacy of kneading massage and phonophoresis in the management of low back pain has not been well documented. The purpose of this study therefore, is to compare the efficacy of kneading massage and phonophoresis using lofnac gel in the treatment of non-specific chronic low back pain.

NCT ID: NCT03316755 Completed - Clinical trials for Periodontal Diseases

Risk Perception of Periodontal Disease

RPPD
Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This study aimed at understanding the impact of educational pamphlet on Risk Perception of Periodontal Disease using A Randomised Clinical Trial model among patients in a Nigerian outpatient dental clinic

NCT ID: NCT03316495 Completed - Clinical trials for Tobacco Use Cessation

IMPACT OF PAMPHLET ON THE KNOWLEDGE OF HEALTH EFFECT OF SMOKING

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Tobacco smoke is one of the most preventable cause of mortality and morbidity worlwide, this study is conducted to compare the knowledge of the health effects of smoking among undergraduates exposed and those not exposed to educational pamphlet. This is designed as a randomized clinical trial among 390 undergraduate in University of Benin Edo State Nigeria. Data collection tool was an interviewer-administered questionnaire. Data obtained would be subjected to regression statistics using IBM SPSS version 21.0. The expected outcome will be a veritable tool in tobacco cessation model.

NCT ID: NCT03306004 Recruiting - Neonatal Jaundice Clinical Trials

Neonatal Jaundice: Knowledge, Attitudes and Practices of Mothers and Medical Trainees and Providers in and Around Ogbomosho

4NNJ
Start date: November 2016
Phase: N/A
Study type: Observational

Determine the knowledge attitude and practices of all levels of health care providers about neonatal jaundice

NCT ID: NCT03303963 Recruiting - Clinical trials for Tuberculosis, Multidrug-Resistant

DIAgnostics for Multidrug Resistant Tuberculosis in Africa

DIAMA
Start date: May 4, 2017
Phase: N/A
Study type: Observational

Recent advances in molecular diagnostics of tuberculosis, especially the GeneXpert Mycobacterium tuberculosis/Rifampicin test have reduced the time to diagnose Rifampicin Resistant Tuberculosis (RR-TB) but only rifampicin resistance is diagnosed, leading to presumptive diagnosis of resistance to isoniazid and maybe other drugs. Thus in low and middle income countries, most drug sensitivity testing relies on phenotypic drug resistance testing, which takes up to 4 months. In addition, currently, culture on monthly sputum samples is recommended by the World Health Organization for follow-up of Rifampicin Resistant Tuberculosis patients under treatment. Unfortunately, culture is often not locally available and samples need to be transported from field to culture laboratories. The associated transport delays lead to high rates of contamination and false negative culture, particularly in laboratories in low resource settings. Many gaps for the diagnosis and management of RR-TB patients still need to be addressed and the DIAMA project (DIAgnostics for Multidrug resistant tuberculosis in Africa) study aims to address some of them.

NCT ID: NCT03284645 Recruiting - Clinical trials for Human Immunodeficiency Virus Infection

Viral and Antiretroviral Dynamics in HIV-1 Mother-to-Child Transmission Fluids

VADICT
Start date: October 20, 2017
Phase: N/A
Study type: Observational

More than 150,000 babies became infected with HIV in 2015 alone. When HIV drugs are started before or early in pregnancy, HIV positive women can give birth to HIV negative baby. This is possible because HIV drugs can reduce the amount of the virus in the body to the extent that they become undetectable by the time of delivery and during the breastfeeding period. However, some women do not start taking these drugs on time because they become infected during pregnancy or lactation. This leads to detectable virus at the time of delivery and puts the baby at risk of becoming infected. Also, the amounts of HIV drugs in the body have to be at certain levels for them to work effectively. But findings from some research have recently showed that pregnancy increases the rate at which the body removes some HIV drugs used to prevent the transfer of HIV from mother to child. While this may not cause any problem in women with no detectable virus before pregnancy, it may affect the rate at which the HIV virus is removed from the body in those starting treatment late and may put the baby at risk. This project will investigate whether the changes in drug exposure caused by pregnancy or other factors have any effect on the rate at which the HIV virus is removed from the body. HIV positive pregnant women and those who recently delivered will be recruited from different hospitals and follow up will be until breastfeeding ends. The investigators will not be involved in treatment decisions and the primary care provider will be responsible for prescribing antiretroviral regimen based on current guidelines. Samples will be collected to measure levels of the virus and the drugs in three fluids that transfer the virus to the baby: blood, genital fluid, and breastmilk. The HIV status of the babies will be monitored until they stop breastfeeding.

NCT ID: NCT03182972 Recruiting - Clinical trials for Medication Reconciliation Implementation

Implementation Study on Medication Reconciliation Among Pharmacists in Two Tertiary Hospitals in Southwestern Nigeria

Start date: August 2, 2016
Phase: N/A
Study type: Interventional

This study will assess the current practice of medication reconciliation among pharmacists in the selected institutions with a view to making an intervention to address gaps discovered

NCT ID: NCT03173729 Recruiting - Colorectal Cancer Clinical Trials

Point of Care Test to Diagnosed Colorectal Cancer and Polyps in Low Middle Income Countries

Start date: February 11, 2017
Phase: N/A
Study type: Observational

This is a-two phase study. Phase 1 will adapt a 3-metabolite biosensor that identifies patients with colorectal cancer (CRC) and precancerous polyps to Nigerian patients. Phase 2 will pilot test and evaluate the point-of-care (POC) biosensor device in Nigeria.