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NCT ID: NCT00359437 Terminated - Liver Cirrhosis Clinical Trials

Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver

SPARe-1
Start date: July 2006
Phase: Phase 3
Study type: Interventional

Primary To evaluate the efficacy of satavaptan on top of diuretic drugs in reducing the recurrence of ascites. Secondary To evaluate the tolerability and safety of satavaptan on top of diuretic drugs over a 52-week treatment period in patients with cirrhosis of the liver and recurrent ascites. The one-year double blind placebo controlled period is extended up to 2 years in a long term safety study (PASCCAL-2).

NCT ID: NCT00359424 Terminated - Stroke Clinical Trials

Interventional Management of Stroke (IMS) III Trial

IMSIII
Start date: August 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare two different treatment approaches to recanalization started within 3 hours of symptom onset—combined intravenous (IV) and endovascular therapy and standard intravenous (IV) rt-PA alone.

NCT ID: NCT00358566 Terminated - Clinical trials for Advanced Unresectable Pancreatic Cancer

GV1001 and Gemcitabine in Sequential Combination to Gemcitabine Monotherapy in Pancreatic Cancer

Start date: June 2006
Phase: Phase 3
Study type: Interventional

To investigate the efficacy of GV1001 in sequential combination with gemcitabine in locally advanced and metastatic adenocarcinoma of the pancreas.

NCT ID: NCT00356629 Terminated - Asthma Clinical Trials

Development of a Noninvasive Method of Evaluation of Pulmonary Inflammation in the Condensates of Exhaled Air

Start date: July 2006
Phase: N/A
Study type: Observational

The aim of the study is identify biological parameters reflecting proteolytic activity in the exhaled condenstaes which might be useful to follow up pulmonary inflammation in various conditions including cystic fibrosis, COPD, asthma, tobacco exposure. Three proteases will be analyzed, i.e. elastase, proteinase 3 and cathepsin G. Results in the condensates will be compared to those obtained in sputum.

NCT ID: NCT00356421 Terminated - Clinical trials for Diabetes Mellitus, Type 1

A Clinical Trial Comparing Efficacy and Safety of Exubera® and Humalog®

Start date: November 2006
Phase: Phase 4
Study type: Interventional

To compare efficacy and safety of Exubera® vs Humalog in patients with type 1 diabetes mellitus

NCT ID: NCT00355901 Terminated - Ulcerative Colitis Clinical Trials

An Observational Follow-up Study for Subjects Receiving Salvage Therapy After Previous Treatment in a Visilizumab Study for Intravenous Steroid-Refractory Ulcerative Colitis

Start date: September 2006
Phase: Phase 2
Study type: Observational

To assess the effects of visilizumab on the safety of subsequent salvage therapies in subjects who experienced disease progression in a previous visilizumab study and subsequently received salvage therapy.

NCT ID: NCT00353574 Terminated - Hypertension Clinical Trials

DORADO-EX: Long-Term Safety Extension Study to the Phase 3 DORADO Study (Protocol DAR-311) of Darusentan in Resistant Hypertension

Darusentan
Start date: September 2006
Phase: Phase 3
Study type: Interventional

This is a research study of a new experimental drug called darusentan. Darusentan is not currently approved by the United States (U.S.) Food and Drug Administration (FDA) for use in the U.S., which means that a doctor cannot prescribe this drug. The purpose of this study is to evaluate the long-term safety of darusentan in subjects with resistant systolic hypertension despite treatment with full doses of three or more antihypertensive medications, including a diuretic.

NCT ID: NCT00348907 Terminated - Pain Clinical Trials

EVENT: Hydrotherapy and Deep Venous Thrombosis

Start date: July 2006
Phase: Phase 3
Study type: Interventional

The main objective of this study is to demonstrate that hydrotherapy in a specific place can reduce the risk of post-thrombotic syndrome.

NCT ID: NCT00348712 Terminated - Clinical trials for Diabetes Mellitus, Type 2

Efficacy and Safety of Inhaled Pre-prandial Human Insulin in Type 2 Diabetes

Start date: October 30, 2006
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this research study is to compare the efficacy of adding inhaled preprandial insulin to metformin compared to adding rosiglitazone to metformin for the treatment of type 2 diabetes and to verify its safety (hypoglycaemia, pulmonary function, body weight, insulin antibodies and side effects).

NCT ID: NCT00346645 Terminated - Clinical trials for STAGE IIIB OR IV NON-SMALL CELL LUNG CANCER

A Phase II Study of Velcade® in Patients Stage IIIB OR IV Non-Small Cell Lung Cancer

Start date: June 2006
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether Bortezomib is effective in the treatment of patients with non-small-cell lung cancer who have not received any prior chemotherapy regimen for advanced disease.