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NCT ID: NCT04184167 Recruiting - Infertility Clinical Trials

Role of Intermittent Fasting Before ICSI

Start date: December 2, 2019
Phase: N/A
Study type: Interventional

intermittent fasting could have a role in infertility

NCT ID: NCT04183244 Recruiting - Postoperative Pain Clinical Trials

Efficacy of Erector Spinae Plane Block Versus Infraclavicular Subomohyoid Block in Shoulder Surgery

Start date: August 15, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The study aimed to compare Erector Spinae Plane (ESP) block versus infraclavicular subomohyoid (ISO) block in the provision of efficacy of either technique in postoperative analgesia in shoulder surgery, aiming to testing the safety of each block in terms of incidence of complications. Patients will be randomly divided into two groups, Group E will receive Erector spinae block and group I will receive infraclavicular subomohyioid block. The local anesthetic solution that will be used in both blocks will be a total volume of 30 mls 0.25%bupivacaine plus 3mg preservative free Dexamethasone. The time between recovery from anesthesia and first pain experienced, as verified by NRS ≥ 3 and first need of a rescue analgesic, will be defined as the duration of analgesia. The total dose of intravenous morphine (the rescue analgesic) used over 24 h postoperatively will be recorded.

NCT ID: NCT04176887 Recruiting - Comparison Clinical Trials

Levetiracetam Versus Phenytoin in Management of Pediatric Status Epilepticus

Start date: January 1, 2019
Phase: Phase 4
Study type: Interventional

The study will be conducted on 60 children suffering from status epilepticus who will be admitted to Pediatric Neurology Unit and Pediatric ICU of Tanta Hospital University.

NCT ID: NCT04173273 Recruiting - Crohn's Disease Clinical Trials

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

CULTIVATE
Start date: January 6, 2020
Phase: Phase 3
Study type: Interventional

This is a Phase 2/3 study that comprises 5 substudies designed to evaluate the efficacy, safety, and tolerability of oral etrasimod as therapy in adult participants with moderately to severely active Crohn's disease (CD) who are refractory or intolerant to at least 1 of the current therapies for CD (ie, corticosteroids, immunosuppressants, or biologics). The overall duration of this study is up to 282 weeks, inclusive of the Screening Period, Treatment Period of up to 274 weeks (Induction, Extension or Maintenance, and Long-term Extension Periods), and the 4-Week Follow-Up Period for safety assessment.

NCT ID: NCT04172558 Recruiting - Clinical trials for Erectile Dysfunction

Intracavernous Injection of Botox 100 U for Treatment of PDE5Is Inconvenient Patients With ED

Start date: March 10, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

There is a new emerging concept that Botulinum Toxin Type A may have a potential role in treatment of erectile dysfunction with a longer duration of action. So, the investigators opted to perform this study to compare ICI of Botulinum Toxin Type A versus Trimix for treatment of ED.

NCT ID: NCT04168177 Recruiting - Pain Management Clinical Trials

Bilateral Erector Spinae Plane Block in Paediateric Cardiac Surgery

Start date: February 17, 2019
Phase: N/A
Study type: Interventional

ultrasound guided erector spinae plane block will be done for childern under going midline sternotomy for cardiac surgery. It is a novel block which is suspected to give powerful analgesia, decrease anaesthetic consumption and decrease awareness on cardiac bypass

NCT ID: NCT04168099 Recruiting - Clinical trials for Spontaneous Bacterial Peritonitis

Oral Gemifloxacin Versus Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis

Start date: December 1, 2018
Phase: Phase 3
Study type: Interventional

oral Gemifloxacin versus intravenous Cefotaxime in treatment of spontaneous bacterial peritonitis

NCT ID: NCT04166357 Recruiting - Clinical trials for Guillain Barre Syndrome

Early Prediction of Respiratory and Autonomic Complications of GBS Using Neuromuscular Ultrasound

Start date: July 1, 2019
Phase:
Study type: Observational

Neuromuscular US will be a good and non invasive predictor for respiratory and autonomic dysfunctions in GBS through evaluation of diaphragmatic thickness, phrenic and vagus nerve cross sectional area.

NCT ID: NCT04166305 Recruiting - Clinical trials for Epilepsy, Drug Resistant

Drug Resistant Epilepsy: Clinical and Genetic Study

Start date: November 1, 2019
Phase:
Study type: Observational

This study is to identify the clinical criteria of drug resistant epilepsy and to explore whether SCN1A c.3184 A/G (rs2298771) and ccl2(rs1024611) polymorphisms could serve as genetic based biomarkers to predict drug resistance among epileptic patient.

NCT ID: NCT04162587 Recruiting - Ischemic Stroke Clinical Trials

Extracranial Carotid & Intracranial Arterial Stenosis in Ischemic Stroke

Start date: May 1, 2019
Phase:
Study type: Observational

The aim of the work is to; elucidate how the presence of carotid stenosis influence the pattern of stroke and also how it interact with other risk factors for stroke. Also identify predictors of intracranial stenosis and outcome in patients with carotid stenosis with or without intracranial stenosis.