Clinical Trials Logo

Filter by:
NCT ID: NCT04161768 Recruiting - Clinical trials for Spontaneous Bacterial Peritonitis

Norfloxacin With Itopride Versus Norfloxacin in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

Start date: December 1, 2018
Phase: Phase 3
Study type: Interventional

Norfloxacin versus Norfloxacin with Itopride in Secondary Prophylaxis of Spontaneous Bacterial Peritonitis

NCT ID: NCT04161053 Recruiting - Clinical trials for Hepatic Encephalopathy

Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic Encephalopathy

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

Efficacy and Safety of Nitazoxanide in preventing recurrence of Hepatic Encephalopathy.

NCT ID: NCT04160598 Recruiting - Clinical trials for Magnesium Infusion in Post-spinal Opioid Pruritis

Effect of Intravenous Magnesium on Post-spinal Fentanyl Induced Pruritus Incidence

Start date: September 2, 2020
Phase: N/A
Study type: Interventional

Introduction: Adding opioids to local anesthetic solutions leads to enhanced anesthesia and provide postoperative analgesia. Intrathecaly injected opioids have some side effects, though. One of them is pruritus. Objective: We designed a randomized, double-blinded, placebo-controlled study to evaluate prophylactic impact of continuous IV Magnesium 10mg/kg over 30 minutes on intrathecal fentanyl-induced pruritus start at the end of the operation. Methods: ASA I-II Patient's candidate for orthopedic operations under spinal anesthesia (10-15mg hyperbaric bupivacaine and 25 µg fentanyl intrathecal) and will be divided randomly into two groups: Control group (Placebo group): bolus 100 ml nacl 0.9% at end of surgery Study group (Mg ++ group): (continuous IV Magnesium 10mg/kg in 100 ml Nacl0.9% over 30 minutes at end of surgery). Study outcome: 1. Hemodynamics: Systolic blood pressure, Mean arterial blood pressure, pulse rate, O2 saturation will be recorded in 5 min,10 min,30 min,60 min and every one hour till 6 hours after the operation. 2. Pruritus Patients were asked about existence (present=1,no=0), severity (mild=1, modret=2, sever =3) and site of pruritus (Face(trigeminal) =1, neuroaxial(dermatome)=2), 1,2,4, and 6 hours after operation. Incidence of pruritus total group incidence %. 3. The incidence of PONV.

NCT ID: NCT04159649 Recruiting - EMBRYO IMPLANTATION Clinical Trials

The Outcomes of ICSI Cycles With and Without Letrozole

Start date: December 1, 2019
Phase: Phase 4
Study type: Interventional

A variety of genes working together with ovarian hormones conducts and precisely control the process of endometrial receptivity and implantation. Leukemia inhibitory factor and αvβ3 integrin are two markers of implantation with at most importance. Reports have emphasized that these important biomarkers have a great role during the process of embryonic implantation. αvβ3 integrin is one of the adhesion molecules which has a critical role in blastocyst apposition and attachment. Many studies have demonstrated that abnormal expression of αvβ3 integrin is associated with poor reproductive outcomes. Other studies haven't found a strong relation between αvβ3 integrin expression and reproductive outcomes Letrozole is an aromatase inhibitor which has been used in controlled ovarian stimulation especially in women with PCOS . Data suggests that letrozole addition to gonadotropins during ovarian stimulation protocols improve the response of the ovaries to FSH in low responders and increase the number of preovulatory follicles without adversely affect the outcomes. Letrozole is used as an adjuvant therapy in ovarian stimulation protocols. So this study aims to evaluate whether the use of letrozole in combination with gonadotropins and GnRH antagonist is superior to gonadotropins and antagonist alone in women undergoing ICSI treatment. Furthermore, both αvβ3 integrin and leukemia inhibitory factor are important markers of endometrial receptivity and implantation. Therefore, this study aims to assess the correlation between mid-luteal gene expression of both αvβ3 integrin and leukemia inhibitory factor and the clinical outcomes of antagonist cycles with or without letrozole.

NCT ID: NCT04158570 Recruiting - Clinical trials for Upper Urinary Tract Stones

Role of Nephrolithometric Scoring Systems in Prediction of PCNL Outcomes in Adult

Start date: October 25, 2019
Phase:
Study type: Observational

Prospective study is to compare between different nephrolithometric scoring systems in prediction of PCNL outcomes in terms of efficacy , success rate and safety in Adult patients with UUT stones unilateral or bilateral, single or multiple, Pelvic or calyceal, primary or recurrent, both gender attending Assuit Urology & Nephrology University Hospital.

NCT ID: NCT04157998 Recruiting - Clinical trials for Aspiration Pneumonia

Ultrasound Assessment of Metoclopramide Effect on Gastric Volume in Cesarean Section

Start date: November 1, 2019
Phase: N/A
Study type: Interventional

the risk of aspiration pneumonitis during cesarean sections has significantly decreased. Nevertheless, precaution against gastric aspiration is still vital in patients in whom regional anesthesia contraindicated or in whom general anesthesia has to be administered (for example; during emergency cesarean delivery). The administration of intravenous anesthetics reduces the level of consciousness of a patient that compromises the protective reflexes of the upper airways. Moreover, a high level of sedation also reduces the tone of the LES (lower oesophageal sphincter). Both these situations predispose the risk of aspiration pneumonia in patients awaiting surgical interventions in supine position under general anesthesia

NCT ID: NCT04157582 Recruiting - Stroke Clinical Trials

Effect of Pilates Training on Cognitive Functions in Patients With Stroke

Start date: October 8, 2019
Phase: N/A
Study type: Interventional

The purpose of the present study is to investigate the effect of pilates training on cognitive functions in patient with stroke

NCT ID: NCT04157283 Recruiting - Multiple Sclerosis Clinical Trials

Sexual Dysfunction in Patients With Relapsing Remitting Multiple Sclerosis and Associated Comorbidities

Start date: November 5, 2019
Phase:
Study type: Observational

This work aims to: 1. Investigate and correlate Sexual Dysfunction in relapsing-remitting Multiple Sclerosis patients with specific focus on 1. Specific neurologic deficit. 2. Depressive symptoms. 3. Comorbid factors. 4. Fatigue symptoms. 2. To investigate the impact of Sexual dysfunction on Sexual Quality of Life (SQoL). 3. To search for possible gender difference.

NCT ID: NCT04154449 Recruiting - Clinical trials for Middle Aged Patients

Effect of Intranasal Insulin on Postoperative Cognitive Dysfunction

Start date: February 25, 2019
Phase:
Study type: Observational

Our study is designed to evaluate the effect of intranasal insulin on postoperative cognitive dysfunction. Primary outcome: 1. The occurrence of cognitive dysfunction at approximately 7 days after surgery. Secondary outcome: 1. Incidence of any side effect.

NCT ID: NCT04153851 Recruiting - Missing Teeth Clinical Trials

Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Study the effect of neurectomy of nasopalatine nerve on the sensation of anterior palate in patients undergoing rehabilitation of anterior maxillary ridge with dental implant