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NCT ID: NCT05627869 Recruiting - Pain Clinical Trials

Effects of TTPB vs PIFB on Opioid Consumption in Patients After Cardiac Surgery.

Start date: February 1, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to compare the effects of TTPB vs PIFB on postoperative opioid consumption in patients undergoing open cardiac surgery.

NCT ID: NCT05627843 Recruiting - Clinical trials for Pediatric Patients Having Renal Failure and on Regular Hemodialysis

Effects of Curcumin on Inflammation and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized, Double-Blind, Placebo-Controlled Pilot Study

Start date: December 1, 2022
Phase: Phase 3
Study type: Interventional

- The study will be a randomised, double blinded, placebo controlled design. - It will include 2 groups : trial group and placebo group - Patients in both groups are children on regular hemodialysis - The patients in the trial group will receive Curcumin capsule 1 gm for 3 months , and the placebo group will receive a placebo capsule for 3 months - All patients will be evaluated clinically, and laboratory at baseline, at 3 months after end of supplementation.

NCT ID: NCT05627830 Recruiting - Pain, Chronic Clinical Trials

Ultrasound Guided Versus Non-Guided Prolotherapy for Internal Derangement of Temporomandibular Joint.

Start date: November 10, 2022
Phase: N/A
Study type: Interventional

Ultrasound Guided Versus Non-Guided Prolotherapy for Treatment of Internal Derangement of Temporomandibular joint. Rationale for conducting the research: The most critical cause for guided prolotherapy is to specify the accurate location of glenoid fossa and the disc space while prolotherapy procedure, and to adjust the needle insertion to according to articular eminence, mandibular condyle, and intra-articular space as anatomical variations. The vibration of ultrasound waves generates a heat so there is a thermal effective for prolotherapy effusion in the TMJ space.

NCT ID: NCT05626933 Recruiting - Clinical trials for Velopharyngeal Insufficiency

Buccinator Myomucosal Flap With Furlow Palatoplasty and VPI

Start date: November 11, 2022
Phase: N/A
Study type: Interventional

Nasopharyngoscopic examination of the 20 patients with secondary VPI following 2 flap palatoplasty will be done for visualization of the velopharyngeal port, allowing assessment of the pattern and grade of velopharyngeal closure during speech and the presence or absence of a velopharyngeal gap and after VPI repair by Buccinator myomucosal flap with Furlow palatoplasty

NCT ID: NCT05626881 Recruiting - Melasma Clinical Trials

Efficacy of Intralesional PRP +/- Topical Silymarin in the Treatment of Melasma

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

Melasma is an acquired disorder of melanogenesis leading to hyperpigmentation and manifested by symmetrical brown to gray-black macules and patches with serrated irregular edges . It occurs especially in sun-exposed areas and affects young to middle-aged women. It is most commonly seen on the face and less commonly on the neck, arms, and chest . Platelet rich plasma (PRP) is defined as a small volume of autologous plasma that contains a high concentration of platelets obtained by centrifugation of autologous blood and subsequent suspension of platelets

NCT ID: NCT05626166 Recruiting - Ulcerative Colitis Clinical Trials

the Efficacy and Safety of Diosmin in Patients With Ulcerative Colitis

Start date: December 15, 2022
Phase: Phase 3
Study type: Interventional

This is a randomized, controlled study evaluating diosmin tablets administered daily for 3 months. The purpose of the study is to evaluate the efficacy and safety of diosmin in the treatment of mild to moderately active ulcerative colitis. Disease activity will be measured using modified truelove and witt's classification.

NCT ID: NCT05626101 Recruiting - Clinical trials for Non-muscle-invasive Bladder Cancer

Safety and Efficacy of Scheduled Intravesical Gemcitabine Versus Intravesical BCG for Intermediate and High Risk Non Muscle Invasive Bladder Cancer: A Prospective, Randomized Study

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

About 40%-80% of NMIBC recur within 6-12 months when managed with TURBT alone, and 10%-25% of the patient's progress to muscle invasive disease. Intravesical therapy enables delivery of high local concentrations of a therapeutic agent within the bladder, which could potentially destroy viable tumor cells that remain following TURBT

NCT ID: NCT05626075 Recruiting - Eye Change Clinical Trials

Correlation Between Corneal Topographic Patterns and Refractive Status Of The Eye in Sohag City,Egypt

Start date: September 22, 2022
Phase: N/A
Study type: Interventional

To evaluate corneal topographic pattern & its correlation with refractive status of the eye .

NCT ID: NCT05624970 Recruiting - Diabetes Clinical Trials

the Effect of Aerobic Training on Insulin Sensitivity on Diabetic Patients During Tobacco Cessation

Start date: November 9, 2022
Phase: N/A
Study type: Interventional

- Prevalence of smoking in men and women ages 15 and over who currently smoke any tobacco product on a daily or non-daily basis Egypt smoking rate for 2018 was 21.40%, a 0.1% increase from 2016. - According to WHO reports, smoking is currently responsible for six million premature deaths every year, of which 600 000 individuals die from the effects of second-hand smoke. - Egypt is one of the 21 countries and territories of the International Diabetes Federation Middle East and North Africa (MENA) region. 463 million people have diabetes in the world and 55 million people in the MENA Region; by 2045 this will rise to 108 million. - The most profound impact of smoking in diabetic patients is on insulin sensitivity, Cigarette smoking worsens insulin-resistance in patients with diabetes, as smoking decreases subcutaneous absorption of insulin, resulting in increased dosing requirements. When the action of insulin is impaired chronically in smokers, a dose response relationship can be seen between the number of cigarettes smoked and the degree of insulin resistance. Consequently, quitting smoking should improve glycemic control. - Therefore diabetic patients can get huge benefits from tobacco cessation as they give their bodies chance to decrease percentage of nicotine and increase percentage of insulin so decrease risk of getting atherosclerosis, so smoking cessation improve glycemic control and insulin sensitivity.

NCT ID: NCT05624866 Recruiting - Clinical trials for Carpal Tunnel Syndrome

Dexmedetomidine Versus Triamcinolone Treatment in Carpal Tunnel Syndrome

Start date: October 10, 2022
Phase: N/A
Study type: Interventional

Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modalities are available for treatment of mild to moderate CTS.