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Pain, Chronic clinical trials

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NCT ID: NCT03727373 Recruiting - Pain, Acute Clinical Trials

Qualitative Study for Pain Measurement Using Innovative Health Technology

Start date: October 17, 2018
Study type: Observational

The present study is a multicenter, explorative, qualitative study. The primary endpoint of this study is to evaluate to which extent the collection of data with regard to pain caused by illness or treatment can be optimized using health technology solutions. For this evaluation semi-structured qualitative interviews with 8-10 patients will be conducted. Secondary variables are the evaluation of the patients' pain experience and the general patients' willingness to collect data with regard to pain by using technological devices themselves or with support of healthcare professionals.

NCT ID: NCT03722394 Completed - Low Back Pain Clinical Trials

Pain Neuroscience Education for Acute and Sub-Acute Low Back Pain

Start date: January 10, 2018
Phase: N/A
Study type: Interventional

To determine if Pain Neuroscience Education (PNE) would result in positive clinical changes in patients presenting with acute or sub-acute low back pain (LBP).

NCT ID: NCT03718325 Not yet recruiting - Pain, Chronic Clinical Trials

Burst Spinal Cord Stimulation (Burst-SCS) Study

Start date: November 2018
Phase: N/A
Study type: Interventional

Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain. The study will examine chronic pain patients who have been deemed candidates for Burst-SCS therapy, and who have already been selected to receive a temporary externalized trial of Burst-SCS from their own doctors as part of their standard clinical care for chronic pain management. During the study, participants will be asked to complete a variety of evaluations at certain time points. In addition, there will be a randomized, double blind, crossover phase, where the particular effects of Burst-SCS and sham SCS will be evaluated. The device used to deliver Burst-SCS and sham SCS is the St. Jude Medical Invisible Trial System.

NCT ID: NCT03703921 Enrolling by invitation - Pain, Chronic Clinical Trials

Neuroimaging of Pain: Changes in Regional Brain Functioning Associated With Amplified Pain and Intensive Treatment

Start date: July 9, 2018
Study type: Observational

The proposed study will examine how intensive interdisciplinary pain treatment (IIPT, specifically the Rehabilitation for Amplified Pain Syndrome, or RAPS, program at Children's Mercy Hospital) impacts neurofunctional mechanisms of emotional and physical pain processing in patients. There has been recent interest in characterizing the brain regions responsible for processing pain (Wager et al., 2013), but little research has included youth. A better understanding of the physiological mechanisms of pain can lead to better treatment outcomes.

NCT ID: NCT03664921 Recruiting - Neuropathic Pain Clinical Trials

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

Start date: November 1, 2018
Phase: Phase 2
Study type: Interventional

This study evaluates the analgesic effect of Omnitram for the treatment of painful diabetic neuropathy. Each subject with diabetic neuropathy will be treated for four weeks with Omnitram and for four weeks with placebo. The order of the Omnitram and placebo treatment will be random.

NCT ID: NCT03649958 Recruiting - Insomnia Clinical Trials

Neurotechnology Following Traumatic Brain Injury

Start date: August 28, 2018
Phase: N/A
Study type: Interventional

This study seeks to improve symptoms such as pain and sleep problems after concussion, or mild traumatic brain injury (mTBI) through a series of 10 office sessions in which musical tones are echoed, or mirrored back in real time, to reflect one's own brain activity. Those who take part in the study will be randomly assigned to receive either tones that are based on their brain activity/brainwaves, or random tones.

NCT ID: NCT03629197 Recruiting - Opioid Use Clinical Trials

Improving Communication About Pain and Opioids

Start date: July 12, 2018
Phase: N/A
Study type: Interventional

The overall goal of this protocol is to pilot test a clinician training intervention that uses standardized patients (trained actors playing patient roles) as instructors who impart communication skills to primary care clinicians. This project will conduct a pilot clinical trial of the intervention developed by the primary investigator in order to evaluate intervention feasibility and generate data to plan a subsequent fully-powered, multisite trial. Primary care clinicians will be randomized to receive either the intervention or control; 48 patients (2 per clinician) will then be recorded during clinic visits with study clinicians and will provide data on post-visit perceptions and health outcomes. Study hypotheses are that visits with clinicians who receive the intervention (versus control) will be associated with more frequent use of targeted communication skills, lower probability of high-risk opioid prescribing, higher patient-reported agreement with treatment plan, and lower pain interference 2 months later.

NCT ID: NCT03597737 Recruiting - Oncology Clinical Trials

Utility of an APP for the Monitoring of Irruptive Oncological Pain

Start date: August 10, 2018
Phase: N/A
Study type: Interventional

The present investigation aims at exploring the effect of including a pain app called Pain Monitor irruptive oncological pain for chronic pain patients' daily monitoring. Two conditions will be set: 1. usual treatment (waiting list) 2. usual treatment + APP

NCT ID: NCT03581591 Recruiting - Pain, Chronic Clinical Trials

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Start date: January 31, 2018
Phase: Phase 3
Study type: Interventional

A 52 week, open label trial to assess the safety and efficacy of KRN23, an investigational antibody to FGF23, in a single pediatric patient with Epidermal Nevus Syndrome(ENS) and associated hypophosphatemic rickets

NCT ID: NCT03569865 Not yet recruiting - Osteoarthritis Clinical Trials

Audio-visual Stimulation: Sleep Dose Response

Start date: October 2018
Phase: N/A
Study type: Interventional

Osteoarthritis (OA) pain affects 50 percent of older adults, more than half of whom also experience significant sleep disturbance. This study examines the impact of an innovative audiovisual stimulation (AVS) program on human brainwaves, and its usefulness to improve sleep. The AVS intervention, if demonstrated to be efficacious for sleep promotion, could benefit millions of people worldwide.