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Velopharyngeal Insufficiency clinical trials

View clinical trials related to Velopharyngeal Insufficiency.

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NCT ID: NCT06343623 Completed - Clinical trials for Velopharyngeal Insufficiency

Superiorly Based Pharyngeal Flap Versus Myomucosal Resection and Direct Closure

Start date: October 12, 2018
Phase: N/A
Study type: Interventional

Patients were classified into two groups. Group (A) patients included fifty patients had velopharyngeal insufficiency and were surgically corrected by the superiorly based pharyngeal flap. Group (B) patients included fifty patients had velopharyngeal insufficiency and were surgically corrected with myomucosal resection and direct closure of the posterior pharyngeal wall

NCT ID: NCT06072495 Recruiting - Cleft Palate Clinical Trials

Etiological Study of Persistent Velopharyngeal Insufficiency in Children With Operated Velopalatine Cleft by Analysis of Velopharyngeal Motor Skills in Static and Dynamic MRI

FENTIRM
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

Velopharyngeal insufficiency is defined as the inability of the soft palate to isolate the nasopharynx from the oropharynx. It is a frequent sequela in patients with a velopalatine cleft despite anatomical restoration of the soft palate by intravelar veloplasty at 6 months. If rehabilitation by a speech therapist is not successful, a pharyngoplasty can be discussed. In the last ten years, MRI was used in dynamic and static way, to analyzed velopharyngeal muscles, in particular Levator Veli Palatini. MRI could be used to identify the etiology of VPI in those patients, and thus allow personalized rehabilitation and surgical management. The aim of this study is to examine the differences in velopharyngeal motricity as well as velar muscles morphology, positioning, and symmetry of children with repaired cleft palate with different degrees of severity of velopharyngeal insufficiency (VPI), and children with labial cleft (noncleft palate anatomy).

NCT ID: NCT05838261 Recruiting - Clinical trials for Velopharyngeal Insufficiency in Children With Isolated or Combined Cleft Palate

Prospective Evaluation of Speech Function Through Patient- and Parent-response Outcome Measurements in Velopharyngeal Insufficiency

Start date: August 24, 2022
Phase:
Study type: Observational

Cleft lip and/or palate (CL/P) is the most common congenital malformation, with about one in 500 children born with CL/P in Sweden, corresponding to approximately 175 births annually. Depending on the extent of the cleft palate, the degree of functional loss varies, but both eating, hearing, speech, bite and appearance can be affected. Patients treated for isolated or combined cleft palate may suffer from velopharyngeal insufficiency (VPI), which means difficulties in closing the passage between the oral and nasal cavities during speech. Velopharyngeal insufficiency is associated with hypernasality, audible nasal air leakage and weak articulation, which might lead to difficulties with communication and social stigmatization. The most common form of speech-improving surgery is a posterior based velopharyngeal flap, creating a bridge between the palate and the posterior pharyngeal wall to more easily compensate for the abnormal airflow through the nose during speech. However, surgical management of VPI is challenging, with variable success rates reported in the literature. In a retrospectively based questionnaire study on patients who underwent surgical treatment of VPI, 30% experienced only a small speech improvement or no improvement at all. In addition, postoperative speech impairment have also been reported, as well as perioperative bleeding and postoperative sleep apnea. Thus, selecting the patients who benefit most from speech-improving surgery is therefore of great importance. The aim with the current study is evaluation of speech function through patient- and parent-response outcome measurements following surgical treatment of velopharyngeal insufficiency in children with isolated or combined cleft palate.

NCT ID: NCT05820529 Recruiting - Clinical trials for Velopharyngeal Insufficiency

Effect of Adenotonsillectomy on Velopharyngeal Valve Mechanism

Start date: February 14, 2023
Phase: N/A
Study type: Interventional

1. To assess safety of tonsillectomy, adenoidectomy or adenotonsillectomy result toVelopharyngeal Valve Mechanism. 2. To predict and prevent post adenotonsillectomy velopharyngeal dysfunction.

NCT ID: NCT05626933 Recruiting - Clinical trials for Velopharyngeal Insufficiency

Buccinator Myomucosal Flap With Furlow Palatoplasty and VPI

Start date: November 11, 2022
Phase: N/A
Study type: Interventional

Nasopharyngoscopic examination of the 20 patients with secondary VPI following 2 flap palatoplasty will be done for visualization of the velopharyngeal port, allowing assessment of the pattern and grade of velopharyngeal closure during speech and the presence or absence of a velopharyngeal gap and after VPI repair by Buccinator myomucosal flap with Furlow palatoplasty

NCT ID: NCT05492266 Not yet recruiting - Clinical trials for Velopharyngeal Insufficiency

Expiratory Muscle Strength Training for Hypernasal Speech in Children

Start date: February 2024
Phase: N/A
Study type: Interventional

When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency. The purpose of this research study is to test if soft palate exercises using a hand help breathing device will help improve the ability of the soft palate to close the area between the throat and nose and help improve speech.

NCT ID: NCT04392817 Completed - Clinical trials for Velopharyngeal Insufficiency

Efficacy of an Arabic Articulatory Error Remediation Software Program in Patients With Velopharyngeal Valve Dysfunction:

Start date: January 2, 2018
Phase: N/A
Study type: Interventional

To develop a remediation software program that is specific for correcting speech errors in patients with velopharyngeal dysfunction in the Arabic language and test its efficacy, on one group comparing pre and post results

NCT ID: NCT04009811 Completed - Clinical trials for Deglutition Disorders

A New Membrane Obturator Prothesis Concept for Soft Palate Defects

VELOMEMBRANE
Start date: July 17, 2020
Phase: N/A
Study type: Interventional

When soft palate defects lead to palatal insufficiency, the patient's quality of life is affected by difficulties swallowing, hypernasality, and poor intelligibility of speech. If immediate surgical reconstruction is not an option, the patient may benefit from the placement of a rigid obturator prosthesis. Unfortunately, the residual muscle stumps are often unable to adequately move this stiff and inert obturator to properly restore the velopharyngeal valve function. The objective of this case report was to describe the use of a membrane obturator prosthesis that incorporates a dental dam to compensate for the soft palate defect.

NCT ID: NCT03898713 Not yet recruiting - Clinical trials for Velopharyngeal Incompetence Due to Cleft Palate

Assessment of Intellectual Abilities for Subjects With Velopharyngeal Incompetence and Their Impact on Speech Intelligibility

Start date: July 1, 2019
Phase:
Study type: Observational

To Assess effect of intelligence on speech production on subjects with velopharyngeal incompetence Search if there is any relation between congenital Velopharyngeal incompetence and decrease IQ of patients

NCT ID: NCT03868891 Terminated - Cleft Palate Clinical Trials

Exercises for Improving Soft Palate and Eustachian Tube Function in Children With Ear Tubes With or Without Cleft Palate

Start date: August 16, 2019
Phase: N/A
Study type: Interventional

Elevation of the soft palate (the soft part of the roof of the mouth) during swallowing helps the Eustachian tube to open and keep the ear healthy. (The Eustachian tube is the normal tube running from the middle ear to the back of the nose and throat). When the soft palate does not move enough (due to a history of cleft palate or for unknown reasons), this can lead to speech problems. Also, because the Eustachian tube is not opening enough, fluid can accumulate in the middle ear, which requires treatment with ear tubes. The goal of this research study is to determine if soft palate exercises will help improve the ability of the soft palate to close the area between the throat and nose, like it is supposed to during speech and swallowing, and if this improves Eustachian tube opening.