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NCT ID: NCT00261963 Completed - Skin Cicatrices Clinical Trials

The Effect of UV-Irradiation on Cutaneous Cicatrices

Start date: February 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the effect of UV-irradiation on human cutaneous cicatrices by clinical examinations and histological, immunohistochemical and biochemical analyses.

NCT ID: NCT00261833 Completed - Emphysema Clinical Trials

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Start date: March 2006
Phase: Phase 4
Study type: Interventional

This is a randomized, placebo-controlled, double-blind, multicenter phase III/IV study to compare the efficacy and safety of Zemaira® with placebo in subjects with emphysema due to alpha1-proteinase inhibitor deficiency. The effect of Zemaira® on the progression of emphysema will be assessed by the decline of lung density, measured by computed tomography (CT).

NCT ID: NCT00261755 Completed - Natural Childbirth Clinical Trials

Acupuncture as Pain Relief and Relaxation During Childbirth

Start date: March 2001
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to investigate the effect of acupuncture for pain relief and relaxation during childbirth.

NCT ID: NCT00261495 Completed - Pain Clinical Trials

A Study of the Effectiveness and Safety of Sustained-release Hydromorphone (a Strong Opioid) in Patients With Chronic Noncancer Pain.

Start date: March 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effectiveness and safety of sustained- release hydromorphone, formulated to release slowly over time, taken once daily, and controlled- release oxycodone taken twice daily, in patients with chronic non-cancer pain. The study will also determine the dose of sustained-release hydromorphone that provides a level of pain control that is equal to the pain control provided by control-released oxycodone (equi-analgesic dosage).

NCT ID: NCT00261365 Completed - Clinical trials for Unresectable Stage III or IV Malignant Melanoma

Phase II Study to Determine Predictive Markers of Response to BMS-734016 (MDX-010)

Start date: November 2005
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to identify candidate markers predictive of response and/or serious toxicity to BMS-734016 (MDX-010).

NCT ID: NCT00260858 Completed - Healthy Clinical Trials

GI Interlab 2 Study: Measuring the Glycaemic Index (GI) of Foods

Start date: November 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the extent of and sources of variation in the glycaemic index values of foods measured by different laboratories around the world.

NCT ID: NCT00260468 Completed - Major Depression Clinical Trials

Brain Abnormalities in Late-Onset Major Depression

Start date: November 2005
Phase: N/A
Study type: Observational

The objective of this project is to examine the state of the brain in people over 50 years old suffering from late-onset depression by means of an extensive clinical assessment programme, including magnetic resonance imaging (MRI), neuropsychological testing, neurological examination, eye examination as well as blood and saliva samples. The results are to be compared with results from a control group matched for gender and age.

NCT ID: NCT00260416 Completed - Clinical trials for Acute Myocardial Infarction

Primary Angioplasty for Acute Myocardial Infarction in Patients With Symptom Duration Above 12 Hours

Start date: May 2005
Phase: Phase 2
Study type: Interventional

Background: Acute balloon angioplasty is beneficial in patients with acute myocardial infarction. However, presently this treatment is not offered to patients with symptom duration above 12 hours. Hypothesis: Acute balloon angioplasty for myocardial infarction is beneficial despite symptom duration above 12 hours. Methods: In 60 patients with myocardial infarction and symptom duration above 12 hours, the proportion of non-perfused myocardium before acute angioplasty and 1 month after angioplasty is compared to evaluate if myocardial tissue can be saved by acute angioplasty despite long symptom duration.

NCT ID: NCT00260338 Completed - Clinical trials for Coronary Heart Disease

Stem Cell Therapy for Vasculogenesis in Patients With Severe Myocardial Ischemia

Start date: December 2005
Phase: Phase 1/Phase 2
Study type: Interventional

Mesenchymal stem cells from the bone marrow can be stimulated to differentiate into endothelial cells and participate in the development of new blood vessels in ischemic tissue. The aim of the study is in a phase I/II safety and efficacy study to evaluate the clinical effect of autologous mesenchymal stem cell therapy in patients with severe chronic myocardial ischemia.

NCT ID: NCT00260260 Completed - Postoperative Pain Clinical Trials

OXY-1: The Pharmacogenetics of Oxycodone Analgesia in Postoperative Pain

Start date: June 2005
Phase: Phase 4
Study type: Interventional

Patients undergoing surgery (thyroidectomy and hysterectomy) will postoperatively receive oxycodone intravenously (IV) as pain management with morphine as an escape medicine, if there is insufficient pain relief with oxycodone. Patients' pain and side effects will be registered and after 24 hours they will answer a questionnaire. All included patients will be genotyped accordingly to CYP2D6 and relevant single nucleotide polymorphisms (SNPs), and measures of plasma levels of oxycodone will be performed.