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NCT ID: NCT00612625 Completed - Clinical trials for Diabetes Mellitus Type 2

Near Normalisation of BG Improves the Potentiating Effect of GLP-1

Start date: February 2004
Phase: N/A
Study type: Interventional

The ability of glucagon-like peptide 1 to enhance beta-cell responsiveness to I.v. glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals. We investigated whether 4 weeks of near-normalisation og blood glucose improves the potentiation of glucose-stimulated insulin secretion by GLP-1

NCT ID: NCT00612599 Completed - Clinical trials for Diabetes Mellitus, Type 2

Comparison of Pharmacodynamics and Pharmacokinetics of Biphasic Insulin Aspart 50 to Biphasic Insulin Aspart 70 in Type 2 Diabetes

Start date: September 2003
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. The aim of this trial is to compare the pharmacodynamics and pharmacokinetics of biphasic insulin aspart 50 three times a day to biphasic insulin aspart 70 three times a day in non-obese and obese with type 2 diabetes.

NCT ID: NCT00612417 Completed - Healthy Clinical Trials

Effect of Recombinant FVIII in Healthy Male Subjects Treated With TB-402

Start date: January 2008
Phase: Phase 1
Study type: Interventional

Single administration of recombinant FVIII/placebo in healthy male subjects who have been treated with a single dose of anti-factor VIII antibody, TB-402

NCT ID: NCT00612300 Completed - Stroke Clinical Trials

Gait Training for Persons With Stroke

GTS
Start date: June 2007
Phase: Phase 0
Study type: Interventional

The objective of this study is to investigate the effects of an automatic gait trainer (Lokomat) handled by physical therapists compared with categorized gait training by physical therapists in ambulatory stroke patients. Gait speed, gait distance and gait symmetry are used to evaluate study effects. Hypotheses: 1) The Lokomat improves stroke patients gait speed, distance and symmetry more than categorized gait training.

NCT ID: NCT00612196 Completed - Healthy Clinical Trials

A Phase I Study of Monoclonal Antibody TB-402 in Healthy Male Volunteers

Start date: March 2007
Phase: Phase 1
Study type: Interventional

Dose escalation study to assess the safety and tolerability of TB-402, a monoclonal antibody directed against FVIII, versus placebo in healthy male volunteers.

NCT ID: NCT00612014 Completed - Diabetes Mellitus Clinical Trials

Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis

Start date: October 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether TZP-101 is effective in the treatment of symptomatic gastroparesis due to diabetes.

NCT ID: NCT00611416 Completed - Obesity Clinical Trials

The Role of Tea Catechins and Caffeine in Relation to Energy Metabolism

Start date: November 2005
Phase: N/A
Study type: Interventional

The aim of this study is to elucidate the role of specific catechins, a mixture of catechins and caffeine in relation to weight control with particular emphasis on energy metabolism and fat oxidation.

NCT ID: NCT00611299 Completed - Clinical trials for Cardiovascular Disease

Dose-Response Study of Probiotic Bacteria BB-12 and CRL-431 in Healthy Young Adults

Start date: April 2003
Phase: Phase 1
Study type: Interventional

The purpose of the study was to investigate the dose-response effect of increasing doses of Bifidobacterium animalis ssp lactis (BB-12) and Lactobacillus paracasei ssp paracasei (CRL-431) on the immune response, blood lipids, gut microflora, recovery from feces and overall tolerance in healthy young adults.

NCT ID: NCT00611156 Completed - Healthy Clinical Trials

Examination of the Effects of Four Different Spices on Energy Metabolism

Start date: October 2006
Phase: N/A
Study type: Interventional

The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism. Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.

NCT ID: NCT00610714 Completed - Ovarian Cancer Clinical Trials

AZD0530 Phase II Study in Patients With Advanced Ovarian Cancer

OVERT-1
Start date: April 2008
Phase: Phase 2
Study type: Interventional

The main purpose of this study is to determine if AZD0530 can improve the efficacy of standard chemotherapy for the treatment of ovarian cancer