Clinical Trials Logo

Filter by:
NCT ID: NCT05754164 Completed - PTSD Clinical Trials

Attention Control Training for the Prevention of PTSD in Firefighters

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The study aimed to examine the effect of Attention Control Training (ACT) intervention on reducing PTSD symptoms in firefighters. The study was a randomized controlled trial carried out in Kunming, China, and involved the recruitment of 180 active firefighters as participants. The intervention lasted for an 8-week duration, during which participants participated in ACT exercises delivered through a smartphone application.

NCT ID: NCT05753878 Completed - COVID-19 Clinical Trials

A Study to Evaluate the Safety and Pharmacokinetics of HH-120 Nasal Spray in Healthy Volunteers

Start date: November 8, 2022
Phase: Phase 1
Study type: Interventional

This is a clinical study evaluating the safety, tolerability, pharmacokinetic (PK) characteristics and immunogenicity of HH-120 nasal spray in healthy subjects. This study is divided into two parts: Part A is of open-label design and mainly aims to assess the local distribution and PK in nasal cavity of HH-120 nasal spray, subjects from 10 cohorts are sequentially enrolled to perform either nasal endoscopic examination or nasal/ nasopharyngeal samples collection at different time points post administration. Part B mainly aims to assess the safety, systematic pharmacokinetic and immunogenicity after multiple dosing of HH-120 nasal spray, subjects are randomly assigned (3:1) to HH-120 and placebo groups.

NCT ID: NCT05753280 Completed - Chronic Hepatitis b Clinical Trials

Effect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHB

Start date: December 1, 2018
Phase: Phase 4
Study type: Interventional

In recent years, vitamin D (VD) has received much attention in the fields of host immune regulation, inflammation, fibrosis, cell proliferation and differentiation and tumor. VD works by binding to the vitamin D receptor (VDR). VDR is mainly distributed in giant cells, dendritic cells, T cells and lymphocytes. Four SNPs of VDRS have been most studied: TaqI (rs731236), FokI (rs10735810), ApaI (rs7975232), and BsmI (rs1544410). At present, more and more patients have been treated with oral nucleotide/nucleoside analogues (NAs) with direct antiviral drugs in China, and a large part of them show low expression of HBsAg. Clinical cure can be pursued for these patients, that is, HBsAg turns negative. A number of studies have been carried out at home and abroad. In this study, We will recruit CHB patients with low HBsAg levels. They all will receive pegylated interferon treatment and were randomly assigned to a vitamin D treatment or a control group. A final assessment will be made to determine whether vitamin D levels would affect the clearance rate of HBsAg.

NCT ID: NCT05753241 Completed - COVID-19 Clinical Trials

the Relationship Between Allergic Rhinitis and the Risk of Symptom in Patients With Mild COVID-19

Start date: November 10, 2022
Phase:
Study type: Observational [Patient Registry]

At present, most studies mainly focussed on severe patients, and there was no comparison of symptom differences between AR patients and healthy people with mild infection to evaluate the symptoms of AR patients during infection and to provide preventive treatment in advance. So this experiment was designed.

NCT ID: NCT05753033 Completed - Healthy Clinical Trials

The Pharmacokinetics (PK), Safety, Tolerability of SR750 in Healthy Volunteers

Start date: February 28, 2023
Phase: Phase 1
Study type: Interventional

This is a randomized, double-blind, placebo-controlled phase I PK bridging study to evaluate the PK, safety and tolerability of SR750 in healthy subjects.

NCT ID: NCT05752175 Completed - COVID-19 Infection Clinical Trials

Study of WPV01 Compared With Placebo in Patients With Mild/Moderate COVID-19 Infection

Start date: March 10, 2023
Phase: Phase 2
Study type: Interventional

A randomized, double-blind, placebo-controlled phase II clinical study to evaluate the efficacy and safety of WPV01 in patients with mild/moderate COVID-19 infection

NCT ID: NCT05751200 Completed - Clinical trials for Type A Aortic Dissection

Safety and Efficacy of Aortic Root Reinforcement Combined With Vascular Grafts Eversion and built-in Procedure (XJ-procedure) in Patients With Acute Type A Aortic Dissection (ADVANCED-XJ )

Start date: March 1, 2023
Phase:
Study type: Observational

This is a retrospective study based on the data available in our hospital database for ATAAD patients from January 2020 to December 2021. These patients were divided into two groups according to the surgical procedures of aortic root. This study compared baseline data, perioperative and short-term follow-up results between the two groups to evaluate the efficacy and safety of XJ-procedure in ATAAD.

NCT ID: NCT05750758 Completed - Clinical trials for Acute Coronary Syndrome

Rivaroxaban Combined With DAPT Versus DAPT Alone After Drug-coated Balloon Angioplasty

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

The target population of this interventional study was ACS patients with drug-coated balloons. The main discussion : 1.1 months of rivaroxaban combined with dual antiplatelet therapy compared with dual antiplatelet therapy alone, late lumen loss at 6 months. 2. To determine the safety of the regimen with bleeding events as the end point. Subjects were randomly assigned to two groups, one receiving routine DAPT for six months and one receiving DAPT plus one month of rivaroxaban 2.5 mg bid

NCT ID: NCT05750745 Completed - Dentin Sensitivity Clinical Trials

A Clinical Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste for the Relief of Dentine Hypersensitivity in a Chinese Population

Start date: May 8, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of the 0.454 percentage (%) weight/weight (w/w) stannous fluoride (SnF2) toothpastes for the relief of dentine hypersensitivity (DH) in China.

NCT ID: NCT05750355 Completed - Healthy Subjects Clinical Trials

Evaluate the Effect of TPN171H on the QT/QTc Interval in Healthy Volunteers

Start date: October 10, 2022
Phase: Phase 1
Study type: Interventional

This is a single-dose orally administered, dose-escalation, single-center, randomized, double-blind, placebo-parallel controlled clinical study evaluating the effect of TPN171H tablets on QT/QTc interval in healthy subjects.The main objective was to evaluate the effect of TPN171H tablets on QT/QTc interval in healthy Chinese subjects after a single oral administration.