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NCT ID: NCT03881774 Recruiting - B Cell Lymphoma Clinical Trials

Cord Blood Derived CAR-T Cells in Refractory/Relapsed B Cell Malignancies

Start date: February 27, 2019
Phase: Phase 1
Study type: Interventional

Evaluation the safety and efficacy of cord blood-derived CAR-T cells in patients with relapsed/refractory B cell leukemia/lymphoma whose disease relapsed after autologous CAR-T cells therapy or who fail to preparation for autologous CAR-T cells

NCT ID: NCT03881761 Recruiting - Refractory Clinical Trials

CD19/20 Bispecific Nanobody-derived CAR-T Cells in B Cell Lymphoma

Start date: February 1, 2019
Phase: Phase 1
Study type: Interventional

Evaluation the safety and efficacy of CD19/CD20 bispecific CAR-T cells in patients with relapsed/refractory B cell lymphoma

NCT ID: NCT03881501 Recruiting - Clinical trials for Hepatocellular Carcinoma Non-resectable

Evaluate the Treatment With Sintilimab Injection Plus Endostar in Hepatocellular Carcinoma

Start date: March 5, 2019
Study type: Observational

It is a a single arm, observational clinical trial to evaluate the efficacy and safety of combination treatment with sintilimab injection plus endostar in untreated locally advanced or metastatic hepatocellular carcinoma.

NCT ID: NCT03881384 Not yet recruiting - Breast Neoplasms Clinical Trials

Circulating Tumor DNA as Marker of Therapeutic Efficacy in Breast Cancer Patients

Start date: April 1, 2019
Study type: Observational

In nonmetastatic local advanced breast cancer patients, we are going to investigate whether circulating tumor DNA (ctDNA) detection can reflect the tumor response to neoadjuvant chemotherapy (NCT) and detect minimal residual disease after surgery.

NCT ID: NCT03881306 Recruiting - Neoplasm Metastasis Clinical Trials

DEBOXA for Inoperable NET Liver Metastases

Start date: July 1, 2018
Phase: Phase 1/Phase 2
Study type: Interventional

A prospective clinical trial to study the safety and effectiveness of Transcatheter Artery Chemotherapy and Embolization (TACE) using CalliSpheres Drug-Eluting Beads with oxaliplatin (DEBOXA) in treating patients who have inoperable neuroendocrine neoplasm (NEN) liver metastases.

NCT ID: NCT03881111 Recruiting - Clinical trials for Esophageal Neoplasms

First-line Esophageal Carcinoma Study With Chemo vs. Chemo Plus Pembrolizumab (MK-3475-590/KEYNOTE-590)-China Extension Study

Start date: January 21, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this Chinese extension study is to evaluate efficacy and safety of pembrolizumab plus cisplatin and 5-fluorouracil (5-FU) chemotherapy versus placebo plus cisplatin and 5-FU chemotherapy as first-line treatment in a Chinese cohort of participants with locally advanced or metastatic esophageal carcinoma. The primary efficacy hypotheses are that both progression-free survival (PFS), according to Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 and determined by blinded independent central review, and overall survival (OS) are superior with pembrolizumab plus chemotherapy compared with placebo plus chemotherapy in all Chinese participants as well as Chinese participants whose tumors are programmed cell death-ligand 1 (PD-L1)-positive.

NCT ID: NCT03881072 Completed - Ultrasonography Clinical Trials

Evaluating the Endometrial Receptivity of FET Patient by Ultrasounicelastography

Start date: October 1, 2017
Phase: N/A
Study type: Interventional

Prospective clinical study :observing the correlation between endometrial elasticity score, endometrial blood flow index (PI, RI, S/D, endometrial thickness, morphology) and clinical pregnancy rate. In order to find a non-invasive, convenient and comprehensive evaluation method of evaluating the endometrial receptivity, and to provide effective means for the frozen embryo transplantation patients to improving pregnancy outcome.

NCT ID: NCT03880929 Completed - Clinical trials for Mucocutaneous Lymph Node Syndrome

Epidemiologic Features of Kawasaki Disease in Shanghai From 2013 Through 2017

Start date: June 1, 2017
Study type: Observational

To investigate the epidemiologic features of Kawasaki disease (KD) in Shanghai from 2013 through 2017 and identify the risk factors for coronary artery lesions.

NCT ID: NCT03880721 Recruiting - Clinical trials for Hepatocellular Carcinoma

By Developing a Radiomics Model to Predict the Prognosis of Patients With Hepatocellular Carcinoma After Microwave Ablation

Start date: January 1, 2019
Study type: Observational

Developing a radiomics model to predict the prognosis of patients with hepatocellular carcinoma after microwave ablation to provide advice for their treatment.

NCT ID: NCT03880708 Recruiting - Clinical trials for Ventricular Arrythmia

China Inherited Ventricular Arrhythmias Registry

Start date: October 24, 2017
Study type: Observational

This is an observational, prospective, multi-center registry, aiming at building a risk stratification for malignant inherited ventricular arrhythmias, including Brugada syndrome(Brs)、Long QT syndrome(LQTS)、Short QT syndrome(SQTS)、Early repolarization syndrome(ERS) and Catecholaminergic polymorphic ventricular tachycardia(CPVT). 500 participants will be recruited from 10 centers in China, with clinical data to be abstracted from medical records, and blood samples to be collected for finding related genes and promising risk indicators. The follow-up should be made every 6 months.